Gene name: IPI3
Reference locus (S288C): YNL182C
Gene biotype: protein_coding
Description: Pre-rRNA-processing protein IPI3; Component of the Rix1 complex and pre-replicative complexes (pre-RCs); required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-RC formation and maintenance during DNA replication licensing; highly conserved protein which contains several WD40 motifs; IPI3 is an essential gene; other members include Rix1p, Ipi1p, and Ipi3p
Top 10 interactors (score): NOG2 (0.999); YTM1 (0.999); IPI1 (0.999); NUG1 (0.999); ARX1 (0.999); RSA4 (0.999); RIX1 (0.999); SDA1 (0.999); NOC3 (0.998); NOG1 (0.997); GRC3 (0.997); NSA2 (0.996); NOP15 (0.996); UTP13 (0.996); UTP4 (0.996); ERB1 (0.995); MDN1 (0.995); LAS1 (0.994); ALB1 (0.994); NOC2 (0.994)
Homologues (species, bitscore): WDR18 (Homo sapiens, 75.5); Wdr18 (Mus musculus, 69.7); wdr18 (Danio rerio, 85.1); wdr18 (Xenopus tropicalis, 97.1); CG14805 (Drosophila melanogaster, 82.8); pro-1 (Caenorhabditis elegans, 63.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:289703-291370:- | gene-YNL182C_AKU4011 | rna-NM_001183020.1_AKU4011 | cds-NP_014217.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:193679-195346:- | gene-YNL182C_BG1 | rna-NM_001183020.1_BG1 | cds-NP_014217.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:299736-301403:- | gene-YNL182C_Bruggeman | rna-NM_001183020.1_Bruggeman | cds-NP_014217.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:342030-343697:- | gene-YNL182C_CAT1 | rna-NM_001183020.1_CAT1 | cds-NP_014217.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:290346-292013:- | gene-YNL182C_CBS1585 | rna-NM_001183020.1_CBS1585 | cds-NP_014217.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:358655-360322:- | gene-YNL182C_CBS436 | rna-NM_001183020.1_CBS436 | cds-NP_014217.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:285760-287427:- | gene-YNL182C_CBS6412 | rna-NM_001183020.1_CBS6412 | cds-NP_014217.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:286779-288446:- | gene-YNL182C_CBS6413 | rna-NM_001183020.1_CBS6413 | cds-NP_014217.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:289788-291455:- | gene-YNL182C_CENPK1137D | rna-NM_001183020.1_CENPK1137D | cds-NP_014217.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:286678-288345:- | gene-YNL182C_EthanolRed | rna-NM_001183020.1_EthanolRed | cds-NP_014217.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:282591-284258:- | gene-YNL182C_FaliES1 | rna-NM_001183020.1_FaliES1 | cds-NP_014217.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000260.1:34264-35931:+ | gene-YNL182C_JAY291 | rna-NM_001183020.1_JAY291 | cds-NP_014217.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:295551-297218:- | gene-YNL182C_MUCL30387 | rna-NM_001183020.1_MUCL30387 | cds-NP_014217.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:329869-331536:- | gene-YNL182C_MUCL30388 | rna-NM_001183020.1_MUCL30388 | cds-NP_014217.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:287585-289252:- | gene-YNL182C_MUCL39482 | rna-NM_001183020.1_MUCL39482 | cds-NP_014217.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:289975-291642:- | gene-YNL182C_MUCL42920 | rna-NM_001183020.1_MUCL42920 | cds-NP_014217.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:295929-297596:- | gene-YNL182C_NCIM3186 | rna-NM_001183020.1_NCIM3186 | cds-NP_014217.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:289679-291346:- | gene-YNL182C_NCYC1407 | rna-NM_001183020.1_NCYC1407 | cds-NP_014217.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:286623-288290:- | gene-YNL182C_PE2H3 | rna-NM_001183020.1_PE2H3 | cds-NP_014217.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:286011-287678:- | gene-YNL182C_PE2H4 | rna-NM_001183020.1_PE2H4 | cds-NP_014217.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:295960-297627:- | gene-YNL182C_S288C | rna-NM_001183020.1_S288C | cds-NP_014217.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:115986-117653:+ | gene-YNL182C_SA1 | rna-NM_001183020.1_SA1 | cds-NP_014217.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:283448-285115:- | gene-YNL182C_ThermosaccDry | rna-NM_001183020.1_ThermosaccDry | cds-NP_014217.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:301947-303614:- | gene-YNL182C_VR1 | rna-NM_001183020.1_VR1 | cds-NP_014217.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:193275-194942:- | gene-YNL182C_ZTW1 | rna-NM_001183020.1_ZTW1 | cds-NP_014217.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:293975-295642:- | gene-YNL182C_Sparadoxus | rna-NM_001183020.1_Sparadoxus | cds-NP_014217.1_Sparadoxus | 88.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |