IPI1 (YHR085W)


Gene profile

Gene name: IPI1
Reference locus (S288C): YHR085W
Gene biotype: protein_coding

Description: Pre-rRNA-processing protein IPI1; Component of the Rix1 complex and possibly pre-replicative complexes; required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-replicative complex (pre-RC) formation and maintenance during DNA replication licensing; relocalizes to the cytosol in response to hypoxia; essential gene; Belongs to the IPI1/TEX10 family

Top 10 interactors (score): NOG2 (0.999); NUG1 (0.999); IPI3 (0.999); NOP7 (0.999); MDN1 (0.999); NOG1 (0.999); NOC3 (0.999); RIX1 (0.999); ARX1 (0.998); DRS1 (0.998); RPF1 (0.998); CIC1 (0.997); ERB1 (0.997); BUD20 (0.997); EBP2 (0.996); PUF6 (0.996); SPB1 (0.996); SSF1 (0.996); MRT4 (0.995); LAS1 (0.995)

Homologues (species, bitscore): TEX10 (Homo sapiens, 62.0); Tex10 (Mus musculus, 55.5); tex10 (Danio rerio, 60.8); tex10 (Xenopus tropicalis, 57.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:263174-264178:+ gene-YHR085W_AKU4011 rna-NM_001179215.1_AKU4011 cds-NP_011953.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:183521-184525:+ gene-YHR085W_BG1 rna-NM_001179215.1_BG1 cds-NP_011953.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:271000-272004:+ gene-YHR085W_Bruggeman rna-NM_001179215.1_Bruggeman cds-NP_011953.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:266141-267145:+ gene-YHR085W_CAT1 rna-NM_001179215.1_CAT1 cds-NP_011953.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:262216-263220:+ gene-YHR085W_CBS1585 rna-NM_001179215.1_CBS1585 cds-NP_011953.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:260080-261084:+ gene-YHR085W_CBS436 rna-NM_001179215.1_CBS436 cds-NP_011953.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:265563-266567:+ gene-YHR085W_CBS6412 rna-NM_001179215.1_CBS6412 cds-NP_011953.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:263255-264259:+ gene-YHR085W_CBS6413 rna-NM_001179215.1_CBS6413 cds-NP_011953.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:269932-270936:+ gene-YHR085W_CENPK1137D rna-NM_001179215.1_CENPK1137D cds-NP_011953.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:322779-323783:+ gene-YHR085W_EthanolRed rna-NM_001179215.1_EthanolRed cds-NP_011953.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:263583-264587:+ gene-YHR085W_FaliES1 rna-NM_001179215.1_FaliES1 cds-NP_011953.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000394.1:46308-47312:+ gene-YHR085W_JAY291 rna-NM_001179215.1_JAY291 cds-NP_011953.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:270521-271525:+ gene-YHR085W_MUCL30387 rna-NM_001179215.1_MUCL30387 cds-NP_011953.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:270383-271387:+ gene-YHR085W_MUCL30388 rna-NM_001179215.1_MUCL30388 cds-NP_011953.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:262539-263543:+ gene-YHR085W_MUCL39482 rna-NM_001179215.1_MUCL39482 cds-NP_011953.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:269286-270290:+ gene-YHR085W_MUCL42920 rna-NM_001179215.1_MUCL42920 cds-NP_011953.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:276646-277650:+ gene-YHR085W_NCIM3186 rna-NM_001179215.1_NCIM3186 cds-NP_011953.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:265003-266007:+ gene-YHR085W_NCYC1407 rna-NM_001179215.1_NCYC1407 cds-NP_011953.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:264673-265677:+ gene-YHR085W_PE2H3 rna-NM_001179215.1_PE2H3 cds-NP_011953.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:272120-273124:+ gene-YHR085W_PE2H4 rna-NM_001179215.1_PE2H4 cds-NP_011953.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:276764-277768:+ gene-YHR085W_S288C rna-NM_001179215.1_S288C cds-NP_011953.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:81220-82224:- gene-YHR085W_SA1 rna-NM_001179215.1_SA1 cds-NP_011953.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:264674-265678:+ gene-YHR085W_ThermosaccDry rna-NM_001179215.1_ThermosaccDry cds-NP_011953.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:272548-273552:+ gene-YHR085W_VR1 rna-NM_001179215.1_VR1 cds-NP_011953.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:256228-257232:+ gene-YHR085W_ZTW1 rna-NM_001179215.1_ZTW1 cds-NP_011953.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:261980-262984:+ gene-YHR085W_Sparadoxus rna-NM_001179215.1_Sparadoxus cds-NP_011953.1_Sparadoxus 87.8 100.0 Verified 1 1 1 False True False False False

Additional files