Gene name: INP53
Reference locus (S288C): YOR109W
Gene biotype: protein_coding
Description: Polyphosphatidylinositol phosphatase; dephosphorylates multiple phosphatidylinositol phosphates; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains; INP53 has a paralog, INP52, that arose from the whole genome duplication; Belongs to the synaptojanin family
Top 10 interactors (score): MSS4 (0.978); PIK1 (0.978); CHC1 (0.975); STT4 (0.974); YMR1 (0.971); SAC1 (0.969); FAB1 (0.96); INP52 (0.958); TEP1 (0.954); LSB6 (0.948); INP51 (0.941); EDE1 (0.939); APL3 (0.926); RVS161 (0.925); PLC1 (0.924); VPS1 (0.922); ARG82 (0.914); DNM1 (0.912); BZZ1 (0.908); YAP1802 (0.906)
Homologues (species, bitscore): SYNJ1 (Homo sapiens, 422.5); Synj1 (Mus musculus, 429.5); synj1 (Danio rerio, 417.9); synj2 (Xenopus tropicalis, 413.3); Synj (Drosophila melanogaster, 394.8); unc-26 (Caenorhabditis elegans, 372.9); ATSAC1B (Arabidopsis thaliana, 207.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:509331-512654:+ | gene-YOR109W_AKU4011 | rna-NM_001183528.3_AKU4011 | cds-NP_014752.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:66407-69730:- | gene-YOR109W_BG1 | rna-NM_001183528.3_BG1 | cds-NP_014752.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:512920-516243:+ | gene-YOR109W_Bruggeman | rna-NM_001183528.3_Bruggeman | cds-NP_014752.3_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:512909-516232:+ | gene-YOR109W_CAT1 | rna-NM_001183528.3_CAT1 | cds-NP_014752.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:504870-508193:+ | gene-YOR109W_CBS1585 | rna-NM_001183528.3_CBS1585 | cds-NP_014752.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:509645-512968:+ | gene-YOR109W_CBS436 | rna-NM_001183528.3_CBS436 | cds-NP_014752.3_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:503382-506705:+ | gene-YOR109W_CBS6412 | rna-NM_001183528.3_CBS6412 | cds-NP_014752.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:510679-514002:+ | gene-YOR109W_CBS6413 | rna-NM_001183528.3_CBS6413 | cds-NP_014752.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:525358-528681:+ | gene-YOR109W_CENPK1137D | rna-NM_001183528.3_CENPK1137D | cds-NP_014752.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:505882-509205:+ | gene-YOR109W_EthanolRed | rna-NM_001183528.3_EthanolRed | cds-NP_014752.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:509384-512707:+ | gene-YOR109W_FaliES1 | rna-NM_001183528.3_FaliES1 | cds-NP_014752.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000063.1:46536-49859:- | gene-YOR109W_JAY291 | rna-NM_001183528.3_JAY291 | cds-NP_014752.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:517478-520801:+ | gene-YOR109W_MUCL30387 | rna-NM_001183528.3_MUCL30387 | cds-NP_014752.3_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:522656-525979:+ | gene-YOR109W_MUCL30388 | rna-NM_001183528.3_MUCL30388 | cds-NP_014752.3_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:512269-515592:+ | gene-YOR109W_MUCL39482 | rna-NM_001183528.3_MUCL39482 | cds-NP_014752.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:528369-531692:+ | gene-YOR109W_MUCL42920 | rna-NM_001183528.3_MUCL42920 | cds-NP_014752.3_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:525167-528490:+ | gene-YOR109W_NCIM3186 | rna-NM_001183528.3_NCIM3186 | cds-NP_014752.3_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:518739-522062:+ | gene-YOR109W_NCYC1407 | rna-NM_001183528.3_NCYC1407 | cds-NP_014752.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:517737-521060:+ | gene-YOR109W_PE2H3 | rna-NM_001183528.3_PE2H3 | cds-NP_014752.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:528114-531437:+ | gene-YOR109W_PE2H4 | rna-NM_001183528.3_PE2H4 | cds-NP_014752.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:525278-528601:+ | gene-YOR109W_S288C | rna-NM_001183528.3_S288C | cds-NP_014752.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:54802-58125:+ | gene-YOR109W_SA1 | rna-NM_001183528.3_SA1 | cds-NP_014752.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:508544-511867:+ | gene-YOR109W_ThermosaccDry | rna-NM_001183528.3_ThermosaccDry | cds-NP_014752.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:510664-513987:+ | gene-YOR109W_VR1 | rna-NM_001183528.3_VR1 | cds-NP_014752.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:242532-245855:+ | gene-YOR109W_ZTW1 | rna-NM_001183528.3_ZTW1 | cds-NP_014752.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:514565-517894:+ | gene-YOR109W_Sparadoxus | rna-NM_001183528.3_Sparadoxus | cds-NP_014752.3_Sparadoxus | 89.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |