INP52 (YNL106C)


Gene profile

Gene name: INP52
Reference locus (S288C): YNL106C
Gene biotype: protein_coding

Description: Polyphosphatidylinositol phosphatase; dephosphorylates a number of phosphatidylinositol phosphates (PtdInsPs, PIPs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain; INP52 has a paralog, INP53, that arose from the whole genome duplication

Top 10 interactors (score): INP51 (0.986); MSS4 (0.984); YMR1 (0.982); RVS161 (0.972); YAP1802 (0.972); STT4 (0.97); EDE1 (0.97); PIK1 (0.967); FAB1 (0.962); RVS167 (0.959); SAC1 (0.958); INP53 (0.958); YAP1801 (0.954); TEP1 (0.948); ABP1 (0.947); PAN1 (0.942); SLA1 (0.938); APL3 (0.929); LSB6 (0.929); END3 (0.925)

Homologues (species, bitscore): SYNJ1 (Homo sapiens, 443.0); Synj1 (Mus musculus, 447.6); synj1 (Danio rerio, 451.8); synj1 (Xenopus tropicalis, 439.9); Synj (Drosophila melanogaster, 424.9); unc-26 (Caenorhabditis elegans, 394.8); ATSAC1B (Arabidopsis thaliana, 214.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:414586-418137:- gene-YNL106C_AKU4011 rna-NM_001182944.1_AKU4011 cds-NP_014293.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:318596-322147:- gene-YNL106C_BG1 rna-NM_001182944.1_BG1 cds-NP_014293.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:425319-428870:- gene-YNL106C_Bruggeman rna-NM_001182944.1_Bruggeman cds-NP_014293.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:468362-471913:- gene-YNL106C_CAT1 rna-NM_001182944.1_CAT1 cds-NP_014293.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:415201-418752:- gene-YNL106C_CBS1585 rna-NM_001182944.1_CBS1585 cds-NP_014293.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:483627-487178:- gene-YNL106C_CBS436 rna-NM_001182944.1_CBS436 cds-NP_014293.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:410674-414225:- gene-YNL106C_CBS6412 rna-NM_001182944.1_CBS6412 cds-NP_014293.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:411677-415228:- gene-YNL106C_CBS6413 rna-NM_001182944.1_CBS6413 cds-NP_014293.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:414795-418346:- gene-YNL106C_CENPK1137D rna-NM_001182944.1_CENPK1137D cds-NP_014293.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:411605-415156:- gene-YNL106C_EthanolRed rna-NM_001182944.1_EthanolRed cds-NP_014293.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:407501-411052:- gene-YNL106C_FaliES1 rna-NM_001182944.1_FaliES1 cds-NP_014293.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000021.1:63883-67434:- gene-YNL106C_JAY291 rna-NM_001182944.1_JAY291 cds-NP_014293.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:421489-425040:- gene-YNL106C_MUCL30387 rna-NM_001182944.1_MUCL30387 cds-NP_014293.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:456879-460430:- gene-YNL106C_MUCL30388 rna-NM_001182944.1_MUCL30388 cds-NP_014293.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:412594-416145:- gene-YNL106C_MUCL39482 rna-NM_001182944.1_MUCL39482 cds-NP_014293.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:416629-420180:- gene-YNL106C_MUCL42920 rna-NM_001182944.1_MUCL42920 cds-NP_014293.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:420913-424464:- gene-YNL106C_NCIM3186 rna-NM_001182944.1_NCIM3186 cds-NP_014293.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:414731-418282:- gene-YNL106C_NCYC1407 rna-NM_001182944.1_NCYC1407 cds-NP_014293.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:413654-417205:- gene-YNL106C_PE2H3 rna-NM_001182944.1_PE2H3 cds-NP_014293.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:413060-416611:- gene-YNL106C_PE2H4 rna-NM_001182944.1_PE2H4 cds-NP_014293.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:420944-424495:- gene-YNL106C_S288C rna-NM_001182944.1_S288C cds-NP_014293.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:5904-9455:- gene-YNL106C_SA1 rna-NM_001182944.1_SA1 cds-NP_014293.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:408373-411924:- gene-YNL106C_ThermosaccDry rna-NM_001182944.1_ThermosaccDry cds-NP_014293.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:427078-430629:- gene-YNL106C_VR1 rna-NM_001182944.1_VR1 cds-NP_014293.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:318192-321743:- gene-YNL106C_ZTW1 rna-NM_001182944.1_ZTW1 cds-NP_014293.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:419284-422844:- gene-YNL106C_Sparadoxus rna-NM_001182944.1_Sparadoxus cds-NP_014293.1_Sparadoxus 87.2 99.7 Verified 1 1 1 False True False False False

Additional files