IML3 (YBR107C)


Gene profile

Gene name: IML3
Reference locus (S288C): YBR107C
Gene biotype: protein_coding

Description: Central kinetochore subunit IML3; Outer kinetochore protein and component of the Ctf19 complex; involved in the establishment of pericentromeric cohesion during mitosis; prevents non-disjunction of sister chromatids during meiosis II; forms a stable complex with Chl4p; required for localization of Sgo1p to pericentric sites during meiosis I; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-L and fission yeast fta1

Top 10 interactors (score): CHL4 (0.999); CTF19 (0.999); CTF3 (0.997); MCM21 (0.997); MCM22 (0.996); MCM16 (0.996); NKP1 (0.995); AME1 (0.994); OKP1 (0.992); NKP2 (0.991); DAM1 (0.974); CSE4 (0.97); SPC19 (0.956); DSN1 (0.951); DAD4 (0.942); SPC34 (0.928); DUO1 (0.924); ASK1 (0.918); DAD3 (0.906); HSK3 (0.904)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:436160-436897:- gene-YBR107C_AKU4011 rna-NM_001178455.3_AKU4011 cds-NP_009665.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:427197-427934:- gene-YBR107C_BG1 rna-NM_001178455.3_BG1 cds-NP_009665.3_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:437934-438671:- gene-YBR107C_Bruggeman rna-NM_001178455.3_Bruggeman cds-NP_009665.3_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:440706-441443:- gene-YBR107C_CAT1 rna-NM_001178455.3_CAT1 cds-NP_009665.3_CAT1 98.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:428443-429180:- gene-YBR107C_CBS1585 rna-NM_001178455.3_CBS1585 cds-NP_009665.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:436563-437300:- gene-YBR107C_CBS436 rna-NM_001178455.3_CBS436 cds-NP_009665.3_CBS436 98.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:526672-527409:- gene-YBR107C_CBS6412 rna-NM_001178455.3_CBS6412 cds-NP_009665.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:433584-434321:- gene-YBR107C_CBS6413 rna-NM_001178455.3_CBS6413 cds-NP_009665.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:445691-446428:- gene-YBR107C_CENPK1137D rna-NM_001178455.3_CENPK1137D cds-NP_009665.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:562949-563686:- gene-YBR107C_EthanolRed rna-NM_001178455.3_EthanolRed cds-NP_009665.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:452232-452969:- gene-YBR107C_FaliES1 rna-NM_001178455.3_FaliES1 cds-NP_009665.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000312.1:23145-23882:- gene-YBR107C_JAY291 rna-NM_001178455.3_JAY291 cds-NP_009665.3_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:439968-440705:- gene-YBR107C_MUCL30387 rna-NM_001178455.3_MUCL30387 cds-NP_009665.3_MUCL30387 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:438970-439707:- gene-YBR107C_MUCL30388 rna-NM_001178455.3_MUCL30388 cds-NP_009665.3_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:426586-427323:- gene-YBR107C_MUCL39482 rna-NM_001178455.3_MUCL39482 cds-NP_009665.3_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:435648-436385:- gene-YBR107C_MUCL42920 rna-NM_001178455.3_MUCL42920 cds-NP_009665.3_MUCL42920 98.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:453590-454327:- gene-YBR107C_NCIM3186 rna-NM_001178455.3_NCIM3186 cds-NP_009665.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:429367-430104:- gene-YBR107C_NCYC1407 rna-NM_001178455.3_NCYC1407 cds-NP_009665.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:441990-442727:- gene-YBR107C_PE2H3 rna-NM_001178455.3_PE2H3 cds-NP_009665.3_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:439666-440403:- gene-YBR107C_PE2H4 rna-NM_001178455.3_PE2H4 cds-NP_009665.3_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:453793-454530:- gene-YBR107C_S288C rna-NM_001178455.3_S288C cds-NP_009665.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000017.1:23181-23918:+ gene-YBR107C_SA1 rna-NM_001178455.3_SA1 cds-NP_009665.3_SA1 98.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:451239-451976:- gene-YBR107C_ThermosaccDry rna-NM_001178455.3_ThermosaccDry cds-NP_009665.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:433250-433987:- gene-YBR107C_VR1 rna-NM_001178455.3_VR1 cds-NP_009665.3_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:426898-427635:- gene-YBR107C_ZTW1 rna-NM_001178455.3_ZTW1 cds-NP_009665.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:463830-464567:- gene-YBR107C_Sparadoxus rna-NM_001178455.3_Sparadoxus cds-NP_009665.3_Sparadoxus 88.7 100.0 Verified 1 1 1 False True False False False

Additional files