Gene name: IML2
Reference locus (S288C): YJL082W
Gene biotype: protein_coding
Description: Mitochondrial outer membrane protein IML2; Protein required for clearance of inclusion bodies; localizes to the inclusion bodies formed under protein misfolding stress; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; IML2 has a paralog, YKR018C, that arose from the whole genome duplication
Top 10 interactors (score): PET10 (0.806); AIM18 (0.749); IML3 (0.748); YDR366C (0.714); PPR1 (0.684); MMO1 (0.671); RIT1 (0.644); URA10 (0.612); CNS1 (0.594); PRP24 (0.57); ENT4 (0.535); OM14 (0.525); ILV2 (0.478); VPS3 (0.473); MVD1 (0.465); UGO1 (0.45); MON1 (0.408); ERG10 (0.404)
Homologues (species, bitscore): TTC39C (Homo sapiens, 80.5); Ttc39c (Mus musculus, 78.6); ttc39c (Danio rerio, 73.6); ttc39b (Xenopus tropicalis, 70.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:263899-266094:+ | gene-YJL082W_AKU4011 | rna-NM_001181515.1_AKU4011 | cds-NP_012453.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:348360-350555:- | gene-YJL082W_BG1 | rna-NM_001181515.1_BG1 | cds-NP_012453.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:275344-277539:+ | gene-YJL082W_Bruggeman | rna-NM_001181515.1_Bruggeman | cds-NP_012453.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:280239-282434:+ | gene-YJL082W_CAT1 | rna-NM_001181515.1_CAT1 | cds-NP_012453.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:275559-277754:+ | gene-YJL082W_CBS1585 | rna-NM_001181515.1_CBS1585 | cds-NP_012453.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:293674-295869:+ | gene-YJL082W_CBS436 | rna-NM_001181515.1_CBS436 | cds-NP_012453.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:264657-266852:+ | gene-YJL082W_CBS6412 | rna-NM_001181515.1_CBS6412 | cds-NP_012453.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:266012-268207:+ | gene-YJL082W_CBS6413 | rna-NM_001181515.1_CBS6413 | cds-NP_012453.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:263649-265844:+ | gene-YJL082W_CENPK1137D | rna-NM_001181515.1_CENPK1137D | cds-NP_012453.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:267749-269944:+ | gene-YJL082W_EthanolRed | rna-NM_001181515.1_EthanolRed | cds-NP_012453.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:279323-281518:+ | gene-YJL082W_FaliES1 | rna-NM_001181515.1_FaliES1 | cds-NP_012453.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000138.1:76944-79139:+ | gene-YJL082W_JAY291 | rna-NM_001181515.1_JAY291 | cds-NP_012453.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:277614-279809:+ | gene-YJL082W_MUCL30387 | rna-NM_001181515.1_MUCL30387 | cds-NP_012453.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:273690-275885:+ | gene-YJL082W_MUCL30388 | rna-NM_001181515.1_MUCL30388 | cds-NP_012453.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:268317-270512:+ | gene-YJL082W_MUCL39482 | rna-NM_001181515.1_MUCL39482 | cds-NP_012453.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:274521-276716:+ | gene-YJL082W_MUCL42920 | rna-NM_001181515.1_MUCL42920 | cds-NP_012453.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:281164-283359:+ | gene-YJL082W_NCIM3186 | rna-NM_001181515.1_NCIM3186 | cds-NP_012453.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:267005-269200:+ | gene-YJL082W_NCYC1407 | rna-NM_001181515.1_NCYC1407 | cds-NP_012453.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:279371-281566:+ | gene-YJL082W_PE2H3 | rna-NM_001181515.1_PE2H3 | cds-NP_012453.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:279015-281210:+ | gene-YJL082W_PE2H4 | rna-NM_001181515.1_PE2H4 | cds-NP_012453.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:281185-283380:+ | gene-YJL082W_S288C | rna-NM_001181515.1_S288C | cds-NP_012453.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:76876-79071:+ | gene-YJL082W_SA1 | rna-NM_001181515.1_SA1 | cds-NP_012453.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:272736-274931:+ | gene-YJL082W_ThermosaccDry | rna-NM_001181515.1_ThermosaccDry | cds-NP_012453.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:274247-276442:+ | gene-YJL082W_VR1 | rna-NM_001181515.1_VR1 | cds-NP_012453.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:254091-256286:+ | gene-YJL082W_ZTW1 | rna-NM_001181515.1_ZTW1 | cds-NP_012453.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:278157-280352:+ | gene-YJL082W_Sparadoxus | rna-NM_001181515.1_Sparadoxus | cds-NP_012453.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |