Gene name: IME4
Reference locus (S288C): YGL192W
Gene biotype: protein_coding
Description: N6-adenosine-methyltransferase IME4; mRNA N6-adenosine methyltransferase required for entry into meiosis; mediates N6-adenosine methylation of bulk mRNA during the induction of sporulation which includes the meiotic regulators IME1, IME2 and IME4 itself; repressed in haploids via production of antisense IME4 transcripts; transcribed in diploid cells where antisense transcription is repressed; orthologous to human METTL3 (MT-A70); Belongs to the MT-A70-like family
Top 10 interactors (score): KAR4 (0.999); SLZ1 (0.968); MUM2 (0.942); IME1 (0.918); IME2 (0.893); SER3 (0.779); PHO92 (0.752); RME1 (0.751); PHO84 (0.749); NDT80 (0.747); GAL10 (0.744); STO1 (0.733); FLO11 (0.718); ZIP2 (0.716); KCS1 (0.697); MATALPHA2 (0.693); HMLALPHA2 (0.691); RQC2 (0.683); MTQ2 (0.653); YFL012W (0.615)
Homologues (species, bitscore): METTL3 (Homo sapiens, 297.7); Mettl3 (Mus musculus, 296.2); mettl3 (Danio rerio, 292.0); mettl3 (Xenopus tropicalis, 294.7); Ime4 (Drosophila melanogaster, 292.4); MTA (Arabidopsis thaliana, 284.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:144782-146584:+ | gene-YGL192W_AKU4011 | rna-NM_001181057.3_AKU4011 | cds-NP_011323.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:263854-265656:- | gene-YGL192W_BG1 | rna-NM_001181057.3_BG1 | cds-NP_011323.3_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:147023-148825:+ | gene-YGL192W_Bruggeman | rna-NM_001181057.3_Bruggeman | cds-NP_011323.3_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:142637-144439:+ | gene-YGL192W_CAT1 | rna-NM_001181057.3_CAT1 | cds-NP_011323.3_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:147921-149723:+ | gene-YGL192W_CBS1585 | rna-NM_001181057.3_CBS1585 | cds-NP_011323.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:142904-144706:+ | gene-YGL192W_CBS436 | rna-NM_001181057.3_CBS436 | cds-NP_011323.3_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:134699-136501:+ | gene-YGL192W_CBS6412 | rna-NM_001181057.3_CBS6412 | cds-NP_011323.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:142233-144035:+ | gene-YGL192W_CBS6413 | rna-NM_001181057.3_CBS6413 | cds-NP_011323.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:142445-144247:+ | gene-YGL192W_CENPK1137D | rna-NM_001181057.3_CENPK1137D | cds-NP_011323.3_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:134765-136567:+ | gene-YGL192W_EthanolRed | rna-NM_001181057.3_EthanolRed | cds-NP_011323.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:135765-137567:+ | gene-YGL192W_FaliES1 | rna-NM_001181057.3_FaliES1 | cds-NP_011323.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000397.1:61095-62897:+ | gene-YGL192W_JAY291 | rna-NM_001181057.3_JAY291 | cds-NP_011323.3_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:144260-146062:+ | gene-YGL192W_MUCL30387 | rna-NM_001181057.3_MUCL30387 | cds-NP_011323.3_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:146587-148724:+ | gene-YGL192W_MUCL30388 | rna-NM_001181057.3_MUCL30388 | cds-NP_011323.3_MUCL30388 | 83.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:144931-146733:+ | gene-YGL192W_MUCL39482 | rna-NM_001181057.3_MUCL39482 | cds-NP_011323.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:147567-149369:+ | gene-YGL192W_MUCL42920 | rna-NM_001181057.3_MUCL42920 | cds-NP_011323.3_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:142246-144048:+ | gene-YGL192W_NCIM3186 | rna-NM_001181057.3_NCIM3186 | cds-NP_011323.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:136413-138215:+ | gene-YGL192W_NCYC1407 | rna-NM_001181057.3_NCYC1407 | cds-NP_011323.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:138407-140209:+ | gene-YGL192W_PE2H3 | rna-NM_001181057.3_PE2H3 | cds-NP_011323.3_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:137955-139757:+ | gene-YGL192W_PE2H4 | rna-NM_001181057.3_PE2H4 | cds-NP_011323.3_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:142246-144048:+ | gene-YGL192W_S288C | rna-NM_001181057.3_S288C | cds-NP_011323.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000067.1:2008-3810:+ | gene-YGL192W_SA1 | rna-NM_001181057.3_SA1 | cds-NP_011323.3_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:136027-137829:+ | gene-YGL192W_ThermosaccDry | rna-NM_001181057.3_ThermosaccDry | cds-NP_011323.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:143311-145113:+ | gene-YGL192W_VR1 | rna-NM_001181057.3_VR1 | cds-NP_011323.3_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:134563-136365:+ | gene-YGL192W_ZTW1 | rna-NM_001181057.3_ZTW1 | cds-NP_011323.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:141434-143242:+ | gene-YGL192W_Sparadoxus | rna-NM_001181057.3_Sparadoxus | cds-NP_011323.3_Sparadoxus | 88.8 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |