Gene name: IMD4
Reference locus (S288C): YML056C
Gene biotype: protein_coding
Description: Inosine-5'-monophosphate dehydrogenase 4; Inosine monophosphate dehydrogenase; catalyzes the rate-limiting step in the de novo synthesis of GTP; member of a four-gene family in S. cerevisiae, constitutively expressed; IMD4 has a paralog, IMD3, that arose from the whole genome duplication
Top 10 interactors (score): GUA1 (0.999); IMD3 (0.999); IMD2 (0.979); ADE12 (0.976); TEF4 (0.959); HPT1 (0.958); AMD1 (0.956); ADE17 (0.948); ADE16 (0.946); HAM1 (0.926); URA7 (0.925); YND1 (0.921); NOP56 (0.918); NKP2 (0.918); ISN1 (0.901); HAS1 (0.876); NOP1 (0.87); CBF5 (0.859); NOP58 (0.851); AAH1 (0.845)
Homologues (species, bitscore): IMPDH1 (Homo sapiens, 660.6); Impdh1 (Mus musculus, 656.4); impdh2 (Danio rerio, 649.4); impdh2 (Xenopus tropicalis, 650.6); ras (Drosophila melanogaster, 624.4); T22D1.3 (Caenorhabditis elegans, 521.2); AT1G16350 (Arabidopsis thaliana, 427.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:155924-157905:- | gene-YML056C_AKU4011 | rna-NM_001182414.1_AKU4011 | cds-NP_013656.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:318262-320245:+ | gene-YML056C_BG1 | rna-NM_001182414.1_BG1 | cds-NP_013656.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:162059-164042:- | gene-YML056C_Bruggeman | rna-NM_001182414.1_Bruggeman | cds-NP_013656.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:163734-166954:- | gene-YML056C_CAT1 | rna-NM_001182414.1_CAT1 | cds-NP_013656.1_CAT1 | 71.9 | 97.5 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:155935-157916:- | gene-YML056C_CBS1585 | rna-NM_001182414.1_CBS1585 | cds-NP_013656.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:161830-163813:- | gene-YML056C_CBS436 | rna-NM_001182414.1_CBS436 | cds-NP_013656.1_CBS436 | 98.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:156643-158624:- | gene-YML056C_CBS6412 | rna-NM_001182414.1_CBS6412 | cds-NP_013656.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:155117-157098:- | gene-YML056C_CBS6413 | rna-NM_001182414.1_CBS6413 | cds-NP_013656.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:156899-158881:- | gene-YML056C_CENPK1137D | rna-NM_001182414.1_CENPK1137D | cds-NP_013656.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:156208-158189:- | gene-YML056C_EthanolRed | rna-NM_001182414.1_EthanolRed | cds-NP_013656.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:156713-158694:- | gene-YML056C_FaliES1 | rna-NM_001182414.1_FaliES1 | cds-NP_013656.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000056.1:1-1265:- | gene-YML056C_JAY291 | rna-NM_001182414.1_JAY291 | cds-NP_013656.1_JAY291 | 54.1 | 54.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:160578-162561:- | gene-YML056C_MUCL30387 | rna-NM_001182414.1_MUCL30387 | cds-NP_013656.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:163766-165749:- | gene-YML056C_MUCL30388 | rna-NM_001182414.1_MUCL30388 | cds-NP_013656.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:155945-157926:- | gene-YML056C_MUCL39482 | rna-NM_001182414.1_MUCL39482 | cds-NP_013656.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:161763-163746:- | gene-YML056C_MUCL42920 | rna-NM_001182414.1_MUCL42920 | cds-NP_013656.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:162148-164130:- | gene-YML056C_NCIM3186 | rna-NM_001182414.1_NCIM3186 | cds-NP_013656.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:156738-158719:- | gene-YML056C_NCYC1407 | rna-NM_001182414.1_NCYC1407 | cds-NP_013656.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:162141-164124:- | gene-YML056C_PE2H3 | rna-NM_001182414.1_PE2H3 | cds-NP_013656.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:162005-163988:- | gene-YML056C_PE2H4 | rna-NM_001182414.1_PE2H4 | cds-NP_013656.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:162194-164176:- | gene-YML056C_S288C | rna-NM_001182414.1_S288C | cds-NP_013656.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000041.1:20048-22031:+ | gene-YML056C_SA1 | rna-NM_001182414.1_SA1 | cds-NP_013656.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:156006-157987:- | gene-YML056C_ThermosaccDry | rna-NM_001182414.1_ThermosaccDry | cds-NP_013656.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:160354-162337:- | gene-YML056C_VR1 | rna-NM_001182414.1_VR1 | cds-NP_013656.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:135529-137510:- | gene-YML056C_ZTW1 | rna-NM_001182414.1_ZTW1 | cds-NP_013656.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:167171-169159:- | gene-YML056C_Sparadoxus | rna-NM_001182414.1_Sparadoxus | cds-NP_013656.1_Sparadoxus | 93.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |