Gene name: IMD3
Reference locus (S288C): YLR432W
Gene biotype: protein_coding
Description: Inosine-5'-monophosphate dehydrogenase 3; Inosine monophosphate dehydrogenase; catalyzes the rate-limiting step in the de novo synthesis of GTP; member of a four-gene family in S. cerevisiae, constitutively expressed; IMD3 has a paralog, IMD4, that arose from the whole genome duplication; Belongs to the IMPDH/GMPR family
Top 10 interactors (score): GUA1 (0.999); IMD4 (0.999); IMD2 (0.996); ADE12 (0.989); HPT1 (0.977); ADE16 (0.969); ADE17 (0.969); AMD1 (0.96); IMD1 (0.953); ISN1 (0.943); URA8 (0.937); HAM1 (0.923); NKP2 (0.918); YAR075W (0.912); YND1 (0.9); URA7 (0.895); ADE13 (0.814); NOP1 (0.811); MUD1 (0.805); URA2 (0.805)
Homologues (species, bitscore): IMPDH1 (Homo sapiens, 656.8); Impdh2 (Mus musculus, 651.7); impdh2 (Danio rerio, 650.6); impdh2 (Xenopus tropicalis, 647.5); ras (Drosophila melanogaster, 628.6); T22D1.3 (Caenorhabditis elegans, 511.9); AT1G16350 (Arabidopsis thaliana, 420.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:940811-942382:+ | gene-YLR432W_AKU4011 | rna-NM_001182320.3_AKU4011 | cds-NP_013536.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:173265-174836:+ | gene-YLR432W_BG1 | rna-NM_001182320.3_BG1 | cds-NP_013536.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:979113-980684:+ | gene-YLR432W_Bruggeman | rna-NM_001182320.3_Bruggeman | cds-NP_013536.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:975131-976702:+ | gene-YLR432W_CAT1 | rna-NM_001182320.3_CAT1 | cds-NP_013536.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:976408-977979:+ | gene-YLR432W_CBS1585 | rna-NM_001182320.3_CBS1585 | cds-NP_013536.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:965753-967324:+ | gene-YLR432W_CBS436 | rna-NM_001182320.3_CBS436 | cds-NP_013536.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:1012448-1014019:+ | gene-YLR432W_CBS6412 | rna-NM_001182320.3_CBS6412 | cds-NP_013536.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:977193-978764:+ | gene-YLR432W_CBS6413 | rna-NM_001182320.3_CBS6413 | cds-NP_013536.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:987174-988745:+ | gene-YLR432W_CENPK1137D | rna-NM_001182320.3_CENPK1137D | cds-NP_013536.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:933839-935410:+ | gene-YLR432W_EthanolRed | rna-NM_001182320.3_EthanolRed | cds-NP_013536.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:969110-970681:+ | gene-YLR432W_FaliES1 | rna-NM_001182320.3_FaliES1 | cds-NP_013536.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000194.1:48009-49580:- | gene-YLR432W_JAY291 | rna-NM_001182320.3_JAY291 | cds-NP_013536.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:977974-979545:+ | gene-YLR432W_MUCL30387 | rna-NM_001182320.3_MUCL30387 | cds-NP_013536.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:985332-986903:+ | gene-YLR432W_MUCL30388 | rna-NM_001182320.3_MUCL30388 | cds-NP_013536.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:977628-979199:+ | gene-YLR432W_MUCL39482 | rna-NM_001182320.3_MUCL39482 | cds-NP_013536.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:978123-979694:+ | gene-YLR432W_MUCL42920 | rna-NM_001182320.3_MUCL42920 | cds-NP_013536.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:1002531-1004102:+ | gene-YLR432W_NCIM3186 | rna-NM_001182320.3_NCIM3186 | cds-NP_013536.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:986807-988627:+ | gene-YLR432W_NCYC1407 | rna-NM_001182320.3_NCYC1407 | cds-NP_013536.3_NCYC1407 | 85.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:973505-975076:+ | gene-YLR432W_PE2H3 | rna-NM_001182320.3_PE2H3 | cds-NP_013536.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:973249-974820:+ | gene-YLR432W_PE2H4 | rna-NM_001182320.3_PE2H4 | cds-NP_013536.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:1002557-1004128:+ | gene-YLR432W_S288C | rna-NM_001182320.3_S288C | cds-NP_013536.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:55834-57405:- | gene-YLR432W_SA1 | rna-NM_001182320.3_SA1 | cds-NP_013536.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:972189-973760:+ | gene-YLR432W_ThermosaccDry | rna-NM_001182320.3_ThermosaccDry | cds-NP_013536.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:978610-980181:+ | gene-YLR432W_VR1 | rna-NM_001182320.3_VR1 | cds-NP_013536.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:302461-304032:+ | gene-YLR432W_ZTW1 | rna-NM_001182320.3_ZTW1 | cds-NP_013536.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:951600-953171:+ | gene-YLR432W_Sparadoxus | rna-NM_001182320.3_Sparadoxus | cds-NP_013536.3_Sparadoxus | 93.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |