Gene name: IMA3
Reference locus (S288C): YIL172C
Gene biotype: protein_coding
Description: Alpha-glucosidase; weak, but broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima3p overexpression allows the ima1 null mutant to grow on isomaltose; lower activitiy and thermostability in vitro than Ima2p despite sequence difference of only 3 amino acids; cleaves alpha-1,3 linkage of nigerose and turanose, but not alpha-1,5 of leucrose; identical to IMA4
Top 10 interactors (score): SUC2 (0.931); SGA1 (0.929); IMA2 (0.858); YEL075W-A (0.813); YLR157W-E (0.81); HXT9 (0.791); YJL218W (0.775); YOL166C (0.766); YLR162W (0.746); ICS2 (0.706); CSS1 (0.703); HPF1 (0.699); HXT13 (0.697); AAD15 (0.693); SEC4 (0.676); REE1 (0.671); SOR1 (0.635); GSY1 (0.582); HXT11 (0.58); ASP3-3 (0.577)
Homologues (species, bitscore): SLC3A1 (Homo sapiens, 193.0); Slc3a1 (Mus musculus, 185.7); slc3a1 (Danio rerio, 217.6); slc3a1 (Xenopus tropicalis, 211.5); Mal-B1 (Drosophila melanogaster, 251.1); atgp-2 (Caenorhabditis elegans, 109.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:17221-18990:- | gene-YIL172C_AKU4011 | rna-NM_001179518.1_AKU4011 | cds-NP_012096.1_AKU4011 | 94.0 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:16981-18749:- | gene-YIL172C_Bruggeman | rna-NM_001179518.1_Bruggeman | cds-NP_012096.1_Bruggeman | 96.0 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:17491-19260:- | gene-YIL172C_CBS1585 | rna-NM_001179518.1_CBS1585 | cds-NP_012096.1_CBS1585 | 88.6 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:9771-11540:- | gene-YIL172C_CBS6413 | rna-NM_001179518.1_CBS6413 | cds-NP_012096.1_CBS6413 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:1-1100:- | gene-YIL172C_CENPK1137D | rna-NM_001179518.1_CENPK1137D | cds-NP_012096.1_CENPK1137D | 62.1 | 62.1 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:17467-19395:- | gene-YIL172C_MUCL30387 | rna-NM_001179518.1_MUCL30387 | cds-NP_012096.1_MUCL30387 | 82.4 | 94.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:794354-796123:+ | gene-YIL172C_MUCL30388 | rna-NM_001179518.1_MUCL30388 | cds-NP_012096.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:17600-19369:- | gene-YIL172C_MUCL39482 | rna-NM_001179518.1_MUCL39482 | cds-NP_012096.1_MUCL39482 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:18153-19923:- | gene-YIL172C_MUCL42920 | rna-NM_001179518.1_MUCL42920 | cds-NP_012096.1_MUCL42920 | 58.9 | 99.5 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:16784-18553:- | gene-YIL172C_NCIM3186 | rna-NM_001179518.1_NCIM3186 | cds-NP_012096.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:13801-15570:- | gene-YIL172C_PE2H4 | rna-NM_001179518.1_PE2H4 | cds-NP_012096.1_PE2H4 | 98.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:16784-18553:- | gene-YIL172C_S288C | rna-NM_001179518.1_S288C | cds-NP_012096.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000176.1:1411-1840:+ | gene-YIL172C_SA1 | rna-NM_001179518.1_SA1 | cds-NP_012096.1_SA1 | 23.5 | 24.2 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:11040-12809:- | gene-YIL172C_Sparadoxus | rna-NM_001179518.1_Sparadoxus | cds-NP_012096.1_Sparadoxus | 90.0 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |