Gene name: IMA2
Reference locus (S288C): YOL157C
Gene biotype: protein_coding
Description: Oligo-1,6-glucosidase IMA2; Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); preferred specificity for isomaltose, alpha-methylglucoside, and palatinose, but also exhibits alpha-1,2 glucosidase activity on sucrose and kojibiose, and can cleave the 1,3-alpha linkage of nigerose and turanose and the alpha-1,5 linkage of leucrose in vitro; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose
Top 10 interactors (score): SUC2 (0.95); SGA1 (0.949); MAL11 (0.938); IMA3 (0.858); MUP1 (0.798); MUP3 (0.767); HXT11 (0.76); MAL31 (0.748); CWH41 (0.718); MAL13 (0.717); MAL33 (0.699); YIL154C (0.692); SEC4 (0.676); YGR125W (0.672); GPH1 (0.66); SCC2 (0.642); PAU20 (0.636); HXT9 (0.602); BIO2 (0.571); AIM20 (0.571)
Homologues (species, bitscore): SLC3A1 (Homo sapiens, 191.8); Slc3a1 (Mus musculus, 184.1); slc3a1 (Danio rerio, 214.5); slc3a1 (Xenopus tropicalis, 210.3); Mal-B1 (Drosophila melanogaster, 248.4); atgp-2 (Caenorhabditis elegans, 108.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000174.1:116781-118550:+ | gene-YOL157C_BG1 | rna-NM_001183410.1_BG1 | cds-NP_014485.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:22422-24211:- | gene-YOL157C_CENPK1137D | rna-NM_001183410.1_CENPK1137D | cds-NP_014485.1_CENPK1137D | 98.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:22414-24183:- | gene-YOL157C_NCIM3186 | rna-NM_001183410.1_NCIM3186 | cds-NP_014485.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:22525-24294:- | gene-YOL157C_S288C | rna-NM_001183410.1_S288C | cds-NP_014485.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:10565-12334:- | gene-YOL157C_ZTW1 | rna-NM_001183410.1_ZTW1 | cds-NP_014485.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:9779-11548:- | gene-YOL157C_Sparadoxus | rna-NM_001183410.1_Sparadoxus | cds-NP_014485.1_Sparadoxus | 90.0 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |