Gene name: ILV2
Reference locus (S288C): YMR108W
Gene biotype: protein_coding
Description: Acetolactate synthase catalytic subunit, mitochondrial; Acetolactate synthase; catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control; Belongs to the TPP enzyme family
Top 10 interactors (score): ILV3 (0.999); ILV5 (0.999); ILV6 (0.999); ILV1 (0.995); LEU2 (0.993); LEU4 (0.992); BAT2 (0.973); LEU9 (0.971); CHA1 (0.958); LEU1 (0.946); MAE1 (0.934); PDB1 (0.928); CYB2 (0.915); TRP5 (0.899); PYC2 (0.879); PDA1 (0.877); MET2 (0.873); CDC19 (0.868); PYK2 (0.843); GDH1 (0.841)
Homologues (species, bitscore): HACL1 (Homo sapiens, 130.2); Hacl1 (Mus musculus, 134.0); hacl1 (Danio rerio, 129.0); hacl1 (Xenopus tropicalis, 127.5); CG11208 (Drosophila melanogaster, 132.9); B0334.3 (Caenorhabditis elegans, 134.0); CSR1 (Arabidopsis thaliana, 458.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:522258-524321:+ | gene-YMR108W_AKU4011 | rna-NM_001182608.1_AKU4011 | cds-NP_013826.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:18515-20578:- | gene-YMR108W_BG1 | rna-NM_001182608.1_BG1 | cds-NP_013826.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:464455-466518:+ | gene-YMR108W_Bruggeman | rna-NM_001182608.1_Bruggeman | cds-NP_013826.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:464760-466823:+ | gene-YMR108W_CAT1 | rna-NM_001182608.1_CAT1 | cds-NP_013826.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:455701-457764:+ | gene-YMR108W_CBS1585 | rna-NM_001182608.1_CBS1585 | cds-NP_013826.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:460628-462691:+ | gene-YMR108W_CBS436 | rna-NM_001182608.1_CBS436 | cds-NP_013826.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:568309-570372:+ | gene-YMR108W_CBS6412 | rna-NM_001182608.1_CBS6412 | cds-NP_013826.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:454462-456525:+ | gene-YMR108W_CBS6413 | rna-NM_001182608.1_CBS6413 | cds-NP_013826.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:478610-480673:+ | gene-YMR108W_CENPK1137D | rna-NM_001182608.1_CENPK1137D | cds-NP_013826.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:455089-457152:+ | gene-YMR108W_EthanolRed | rna-NM_001182608.1_EthanolRed | cds-NP_013826.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:459099-461162:+ | gene-YMR108W_FaliES1 | rna-NM_001182608.1_FaliES1 | cds-NP_013826.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000380.1:18394-20457:- | gene-YMR108W_JAY291 | rna-NM_001182608.1_JAY291 | cds-NP_013826.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:461376-463439:+ | gene-YMR108W_MUCL30387 | rna-NM_001182608.1_MUCL30387 | cds-NP_013826.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:465365-467428:+ | gene-YMR108W_MUCL30388 | rna-NM_001182608.1_MUCL30388 | cds-NP_013826.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:455502-457565:+ | gene-YMR108W_MUCL39482 | rna-NM_001182608.1_MUCL39482 | cds-NP_013826.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:462280-464343:+ | gene-YMR108W_MUCL42920 | rna-NM_001182608.1_MUCL42920 | cds-NP_013826.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:484038-486101:+ | gene-YMR108W_NCIM3186 | rna-NM_001182608.1_NCIM3186 | cds-NP_013826.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:455398-457461:+ | gene-YMR108W_NCYC1407 | rna-NM_001182608.1_NCYC1407 | cds-NP_013826.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:461226-463289:+ | gene-YMR108W_PE2H3 | rna-NM_001182608.1_PE2H3 | cds-NP_013826.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:467321-469384:+ | gene-YMR108W_PE2H4 | rna-NM_001182608.1_PE2H4 | cds-NP_013826.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:484084-486147:+ | gene-YMR108W_S288C | rna-NM_001182608.1_S288C | cds-NP_013826.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000048.1:85434-87497:- | gene-YMR108W_SA1 | rna-NM_001182608.1_SA1 | cds-NP_013826.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:456075-458138:+ | gene-YMR108W_ThermosaccDry | rna-NM_001182608.1_ThermosaccDry | cds-NP_013826.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:467812-469875:+ | gene-YMR108W_VR1 | rna-NM_001182608.1_VR1 | cds-NP_013826.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:432108-434171:+ | gene-YMR108W_ZTW1 | rna-NM_001182608.1_ZTW1 | cds-NP_013826.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:469069-471132:+ | gene-YMR108W_Sparadoxus | rna-NM_001182608.1_Sparadoxus | cds-NP_013826.1_Sparadoxus | 92.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |