IKS1 (YJL057C)


Gene profile

Gene name: IKS1
Reference locus (S288C): YJL057C
Gene biotype: protein_coding

Description: Probable serine/threonine-protein kinase IKS1; Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p

Top 10 interactors (score): MCP2 (0.714); SCY1 (0.711); RPO41 (0.707); ZNF1 (0.704); ISR1 (0.696); KKQ8 (0.696); SAK1 (0.693); BUD32 (0.692); GEF1 (0.691); PKP1 (0.684); SEC4 (0.653); STE11 (0.653); RHO5 (0.647); MYO2 (0.632); TOS3 (0.623); EXO5 (0.613); RIE1 (0.611); FMP48 (0.611); VPS70 (0.61); YPL150W (0.588)

Homologues (species, bitscore): EIF2AK2 (Homo sapiens, 80.9); Eif2ak2 (Mus musculus, 72.8); camk1db (Danio rerio, 65.5); camk1g (Xenopus tropicalis, 76.6); Gcn2 (Drosophila melanogaster, 74.3); pig-1 (Caenorhabditis elegans, 63.2); NEK5 (Arabidopsis thaliana, 68.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:310981-312984:- gene-YJL057C_AKU4011 rna-NM_001181490.3_AKU4011 cds-NP_012478.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:300860-302863:+ gene-YJL057C_BG1 rna-NM_001181490.3_BG1 cds-NP_012478.3_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:323516-325519:- gene-YJL057C_Bruggeman rna-NM_001181490.3_Bruggeman cds-NP_012478.3_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:327627-329630:- gene-YJL057C_CAT1 rna-NM_001181490.3_CAT1 cds-NP_012478.3_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:322635-324638:- gene-YJL057C_CBS1585 rna-NM_001181490.3_CBS1585 cds-NP_012478.3_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:340645-342645:- gene-YJL057C_CBS436 rna-NM_001181490.3_CBS436 cds-NP_012478.3_CBS436 99.2 99.8 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:311739-313742:- gene-YJL057C_CBS6412 rna-NM_001181490.3_CBS6412 cds-NP_012478.3_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:313086-315089:- gene-YJL057C_CBS6413 rna-NM_001181490.3_CBS6413 cds-NP_012478.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:310586-312589:- gene-YJL057C_CENPK1137D rna-NM_001181490.3_CENPK1137D cds-NP_012478.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:314818-316821:- gene-YJL057C_EthanolRed rna-NM_001181490.3_EthanolRed cds-NP_012478.3_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:326393-328396:- gene-YJL057C_FaliES1 rna-NM_001181490.3_FaliES1 cds-NP_012478.3_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000138.1:123983-125986:- gene-YJL057C_JAY291 rna-NM_001181490.3_JAY291 cds-NP_012478.3_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:324671-326674:- gene-YJL057C_MUCL30387 rna-NM_001181490.3_MUCL30387 cds-NP_012478.3_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:320708-322711:- gene-YJL057C_MUCL30388 rna-NM_001181490.3_MUCL30388 cds-NP_012478.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:315389-317392:- gene-YJL057C_MUCL39482 rna-NM_001181490.3_MUCL39482 cds-NP_012478.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:322039-324039:- gene-YJL057C_MUCL42920 rna-NM_001181490.3_MUCL42920 cds-NP_012478.3_MUCL42920 99.3 99.8 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:328097-330100:- gene-YJL057C_NCIM3186 rna-NM_001181490.3_NCIM3186 cds-NP_012478.3_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:314085-316088:- gene-YJL057C_NCYC1407 rna-NM_001181490.3_NCYC1407 cds-NP_012478.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:326437-328440:- gene-YJL057C_PE2H3 rna-NM_001181490.3_PE2H3 cds-NP_012478.3_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:326082-328085:- gene-YJL057C_PE2H4 rna-NM_001181490.3_PE2H4 cds-NP_012478.3_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:328118-330121:- gene-YJL057C_S288C rna-NM_001181490.3_S288C cds-NP_012478.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:124000-126003:- gene-YJL057C_SA1 rna-NM_001181490.3_SA1 cds-NP_012478.3_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:319806-321809:- gene-YJL057C_ThermosaccDry rna-NM_001181490.3_ThermosaccDry cds-NP_012478.3_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:321999-324002:- gene-YJL057C_VR1 rna-NM_001181490.3_VR1 cds-NP_012478.3_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:301183-303186:- gene-YJL057C_ZTW1 rna-NM_001181490.3_ZTW1 cds-NP_012478.3_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:325205-327208:- gene-YJL057C_Sparadoxus rna-NM_001181490.3_Sparadoxus cds-NP_012478.3_Sparadoxus 90.6 100.0 Verified 1 1 1 False True False False False

Additional files