Gene name: IKI3
Reference locus (S288C): YLR384C
Gene biotype: protein_coding
Description: Subunit of Elongator complex; Elongator is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)
Top 10 interactors (score): ELP6 (0.999); IKI1 (0.999); ELP2 (0.999); ELP4 (0.999); ELP3 (0.999); KTI12 (0.997); NCS6 (0.987); UBA4 (0.978); URM1 (0.976); KTI11 (0.974); NCS2 (0.961); MCM5 (0.944); HRR25 (0.935); RPA135 (0.916); DRS1 (0.911); HHT2 (0.907); NOC3 (0.907); PUF6 (0.906); MDN1 (0.906); SIT4 (0.901)
Homologues (species, bitscore): IKBKAP (Homo sapiens, 485.7); Ikbkap (Mus musculus, 478.0); ikbkap (Danio rerio, 206.5); elp1 (Xenopus tropicalis, 441.4); Elp1 (Drosophila melanogaster, 334.3); elpc-1 (Caenorhabditis elegans, 134.8); ABO1 (Arabidopsis thaliana, 269.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:838388-842437:- | gene-YLR384C_AKU4011 | rna-NM_001182273.3_AKU4011 | cds-NP_013488.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:70566-74615:- | gene-YLR384C_BG1 | rna-NM_001182273.3_BG1 | cds-NP_013488.3_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:876694-880743:- | gene-YLR384C_Bruggeman | rna-NM_001182273.3_Bruggeman | cds-NP_013488.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:872219-876268:- | gene-YLR384C_CAT1 | rna-NM_001182273.3_CAT1 | cds-NP_013488.3_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:873984-878033:- | gene-YLR384C_CBS1585 | rna-NM_001182273.3_CBS1585 | cds-NP_013488.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:857624-861673:- | gene-YLR384C_CBS436 | rna-NM_001182273.3_CBS436 | cds-NP_013488.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:910025-914074:- | gene-YLR384C_CBS6412 | rna-NM_001182273.3_CBS6412 | cds-NP_013488.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:874275-878324:- | gene-YLR384C_CBS6413 | rna-NM_001182273.3_CBS6413 | cds-NP_013488.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:873629-877714:- | gene-YLR384C_CENPK1137D | rna-NM_001182273.3_CENPK1137D | cds-NP_013488.3_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:830930-834979:- | gene-YLR384C_EthanolRed | rna-NM_001182273.3_EthanolRed | cds-NP_013488.3_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:860240-864289:- | gene-YLR384C_FaliES1 | rna-NM_001182273.3_FaliES1 | cds-NP_013488.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000434.1:13399-17448:- | gene-YLR384C_JAY291 | rna-NM_001182273.3_JAY291 | cds-NP_013488.3_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:875205-879254:- | gene-YLR384C_MUCL30387 | rna-NM_001182273.3_MUCL30387 | cds-NP_013488.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:881645-885694:- | gene-YLR384C_MUCL30388 | rna-NM_001182273.3_MUCL30388 | cds-NP_013488.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:875204-879253:- | gene-YLR384C_MUCL39482 | rna-NM_001182273.3_MUCL39482 | cds-NP_013488.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:869861-873910:- | gene-YLR384C_MUCL42920 | rna-NM_001182273.3_MUCL42920 | cds-NP_013488.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:888825-892874:- | gene-YLR384C_NCIM3186 | rna-NM_001182273.3_NCIM3186 | cds-NP_013488.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:884384-888433:- | gene-YLR384C_NCYC1407 | rna-NM_001182273.3_NCYC1407 | cds-NP_013488.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:870778-874827:- | gene-YLR384C_PE2H3 | rna-NM_001182273.3_PE2H3 | cds-NP_013488.3_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:870522-874571:- | gene-YLR384C_PE2H4 | rna-NM_001182273.3_PE2H4 | cds-NP_013488.3_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:888851-892900:- | gene-YLR384C_S288C | rna-NM_001182273.3_S288C | cds-NP_013488.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:155788-159837:+ | gene-YLR384C_SA1 | rna-NM_001182273.3_SA1 | cds-NP_013488.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:863319-867368:- | gene-YLR384C_ThermosaccDry | rna-NM_001182273.3_ThermosaccDry | cds-NP_013488.3_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:875868-879917:- | gene-YLR384C_VR1 | rna-NM_001182273.3_VR1 | cds-NP_013488.3_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:200036-204085:- | gene-YLR384C_ZTW1 | rna-NM_001182273.3_ZTW1 | cds-NP_013488.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:848719-852784:- | gene-YLR384C_Sparadoxus | rna-NM_001182273.3_Sparadoxus | cds-NP_013488.3_Sparadoxus | 90.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |