Gene name: IFA38
Reference locus (S288C): YBR159W
Gene biotype: protein_coding
Description: Very-long-chain 3-oxoacyl-CoA reductase; Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides; Belongs to the short-chain dehydrogenases/reductases (SDR) family
Top 10 interactors (score): TSC13 (0.996); PHS1 (0.995); ELO2 (0.992); ELO3 (0.988); ELO1 (0.987); OLE1 (0.962); ERG27 (0.916); OAR1 (0.88); ERG7 (0.865); AYR1 (0.823); ERG26 (0.82); NFS1 (0.777); ACC1 (0.767); YDL114W (0.763); ERG25 (0.758); FAS1 (0.756); YOR345C (0.745); YGL072C (0.712); FAS2 (0.706); CYS4 (0.702)
Homologues (species, bitscore): HSD17B12 (Homo sapiens, 159.5); Hsd17b12 (Mus musculus, 154.5); hsd17b12b (Danio rerio, 161.4); hsd17b12 (Xenopus tropicalis, 161.4); CG1444 (Drosophila melanogaster, 161.0); let-767 (Caenorhabditis elegans, 131.7); KCR1 (Arabidopsis thaliana, 156.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:541567-542610:+ | gene-YBR159W_AKU4011 | rna-NM_001178507.1_AKU4011 | cds-NP_009717.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:532133-533176:+ | gene-YBR159W_BG1 | rna-NM_001178507.1_BG1 | cds-NP_009717.1_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:544606-545649:+ | gene-YBR159W_Bruggeman | rna-NM_001178507.1_Bruggeman | cds-NP_009717.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:438707-439750:+ | gene-YBR159W_CAT1 | rna-NM_001178507.1_CAT1 | cds-NP_009717.1_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:533344-534387:+ | gene-YBR159W_CBS1585 | rna-NM_001178507.1_CBS1585 | cds-NP_009717.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:541442-542485:+ | gene-YBR159W_CBS436 | rna-NM_001178507.1_CBS436 | cds-NP_009717.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:631212-632191:+ | gene-YBR159W_CBS6412 | rna-NM_001178507.1_CBS6412 | cds-NP_009717.1_CBS6412 | 79.5 | 90.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:538981-540024:+ | gene-YBR159W_CBS6413 | rna-NM_001178507.1_CBS6413 | cds-NP_009717.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:552461-553504:+ | gene-YBR159W_CENPK1137D | rna-NM_001178507.1_CENPK1137D | cds-NP_009717.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:667587-668606:+ | gene-YBR159W_EthanolRed | rna-NM_001178507.1_EthanolRed | cds-NP_009717.1_EthanolRed | 91.4 | 95.8 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:557599-558642:+ | gene-YBR159W_FaliES1 | rna-NM_001178507.1_FaliES1 | cds-NP_009717.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000322.1:1520-2563:- | gene-YBR159W_JAY291 | rna-NM_001178507.1_JAY291 | cds-NP_009717.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:546233-547276:+ | gene-YBR159W_MUCL30387 | rna-NM_001178507.1_MUCL30387 | cds-NP_009717.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:545527-546570:+ | gene-YBR159W_MUCL30388 | rna-NM_001178507.1_MUCL30388 | cds-NP_009717.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:531731-532774:+ | gene-YBR159W_MUCL39482 | rna-NM_001178507.1_MUCL39482 | cds-NP_009717.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:541627-542670:+ | gene-YBR159W_MUCL42920 | rna-NM_001178507.1_MUCL42920 | cds-NP_009717.1_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:558482-559525:+ | gene-YBR159W_NCIM3186 | rna-NM_001178507.1_NCIM3186 | cds-NP_009717.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:534283-535326:+ | gene-YBR159W_NCYC1407 | rna-NM_001178507.1_NCYC1407 | cds-NP_009717.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:546918-547961:+ | gene-YBR159W_PE2H3 | rna-NM_001178507.1_PE2H3 | cds-NP_009717.1_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:544594-545637:+ | gene-YBR159W_PE2H4 | rna-NM_001178507.1_PE2H4 | cds-NP_009717.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:558685-559728:+ | gene-YBR159W_S288C | rna-NM_001178507.1_S288C | cds-NP_009717.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000032.1:79862-80905:+ | gene-YBR159W_SA1 | rna-NM_001178507.1_SA1 | cds-NP_009717.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:556612-557655:+ | gene-YBR159W_ThermosaccDry | rna-NM_001178507.1_ThermosaccDry | cds-NP_009717.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:538108-539151:+ | gene-YBR159W_VR1 | rna-NM_001178507.1_VR1 | cds-NP_009717.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:531758-532801:+ | gene-YBR159W_ZTW1 | rna-NM_001178507.1_ZTW1 | cds-NP_009717.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:568970-570013:+ | gene-YBR159W_Sparadoxus | rna-NM_001178507.1_Sparadoxus | cds-NP_009717.1_Sparadoxus | 89.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |