Gene name: IES6
Reference locus (S288C): YEL044W
Gene biotype: protein_coding
Description: Chromatin-remodeling complex subunit IES6; Component of the INO80 chromatin remodeling complex; critical for INO80 function; involved in regulation of chromosome segregation and maintenance of normal centromeric chromatin structure; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes; Belongs to the IES6 family
Top 10 interactors (score): RVB2 (0.999); RVB1 (0.999); ARP5 (0.999); INO80 (0.997); IES5 (0.99); IES3 (0.989); ARP8 (0.986); IES4 (0.984); NHP10 (0.983); IES1 (0.976); ARP4 (0.97); ACT1 (0.97); IES2 (0.969); TAF14 (0.955); VPS72 (0.923); YAF9 (0.912); SWC7 (0.897); SWC4 (0.881); SWR1 (0.858); DIB1 (0.816)
Homologues (species, bitscore): INO80C (Homo sapiens, 52.8); Ino80c (Mus musculus, 54.3); ino80c (Danio rerio, 50.8); DmelCG12659 (Drosophila melanogaster, 50.8); AT4G38495 (Arabidopsis thaliana, 63.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:63819-64319:+ | gene-YEL044W_AKU4011 | rna-NM_001178859.1_AKU4011 | cds-NP_010870.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000075.1:16230-16730:- | gene-YEL044W_BG1 | rna-NM_001178859.1_BG1 | cds-NP_010870.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:67961-68461:+ | gene-YEL044W_Bruggeman | rna-NM_001178859.1_Bruggeman | cds-NP_010870.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:65751-66251:+ | gene-YEL044W_CAT1 | rna-NM_001178859.1_CAT1 | cds-NP_010870.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:63765-64265:+ | gene-YEL044W_CBS1585 | rna-NM_001178859.1_CBS1585 | cds-NP_010870.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:65394-65894:+ | gene-YEL044W_CBS436 | rna-NM_001178859.1_CBS436 | cds-NP_010870.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:64017-64517:+ | gene-YEL044W_CBS6412 | rna-NM_001178859.1_CBS6412 | cds-NP_010870.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:68657-69157:+ | gene-YEL044W_CBS6413 | rna-NM_001178859.1_CBS6413 | cds-NP_010870.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:67611-68111:+ | gene-YEL044W_CENPK1137D | rna-NM_001178859.1_CENPK1137D | cds-NP_010870.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:63572-64072:+ | gene-YEL044W_EthanolRed | rna-NM_001178859.1_EthanolRed | cds-NP_010870.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:63835-64335:+ | gene-YEL044W_FaliES1 | rna-NM_001178859.1_FaliES1 | cds-NP_010870.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000022.1:15481-15981:- | gene-YEL044W_JAY291 | rna-NM_001178859.1_JAY291 | cds-NP_010870.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:68017-68517:+ | gene-YEL044W_MUCL30387 | rna-NM_001178859.1_MUCL30387 | cds-NP_010870.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:63876-64376:+ | gene-YEL044W_MUCL30388 | rna-NM_001178859.1_MUCL30388 | cds-NP_010870.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:63134-63634:+ | gene-YEL044W_MUCL39482 | rna-NM_001178859.1_MUCL39482 | cds-NP_010870.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:67767-68267:+ | gene-YEL044W_MUCL42920 | rna-NM_001178859.1_MUCL42920 | cds-NP_010870.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:69756-70256:+ | gene-YEL044W_NCIM3186 | rna-NM_001178859.1_NCIM3186 | cds-NP_010870.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:68228-68728:+ | gene-YEL044W_NCYC1407 | rna-NM_001178859.1_NCYC1407 | cds-NP_010870.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:72252-72752:+ | gene-YEL044W_PE2H3 | rna-NM_001178859.1_PE2H3 | cds-NP_010870.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:68167-68667:+ | gene-YEL044W_PE2H4 | rna-NM_001178859.1_PE2H4 | cds-NP_010870.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:69757-70257:+ | gene-YEL044W_S288C | rna-NM_001178859.1_S288C | cds-NP_010870.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000053.1:16327-16827:- | gene-YEL044W_SA1 | rna-NM_001178859.1_SA1 | cds-NP_010870.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:64234-64734:+ | gene-YEL044W_ThermosaccDry | rna-NM_001178859.1_ThermosaccDry | cds-NP_010870.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:63455-63955:+ | gene-YEL044W_VR1 | rna-NM_001178859.1_VR1 | cds-NP_010870.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:63167-63667:+ | gene-YEL044W_ZTW1 | rna-NM_001178859.1_ZTW1 | cds-NP_010870.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |