Gene name: IDP2
Reference locus (S288C): YLR174W
Gene biotype: protein_coding
Description: Cytosolic NADP-specific isocitrate dehydrogenase; catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose; IDP2 has a paralog, IDP3, that arose from the whole genome duplication
Top 10 interactors (score): CAT2 (0.993); IDH1 (0.992); IDH2 (0.992); FBP1 (0.987); MLS1 (0.986); ICL1 (0.982); IDP3 (0.982); PCK1 (0.981); ACO1 (0.98); SFC1 (0.979); KGD1 (0.976); FOX2 (0.968); AAT1 (0.966); POX1 (0.965); SPS19 (0.947); ZWF1 (0.939); JEN1 (0.93); GDH1 (0.924); TES1 (0.92); GDH2 (0.916)
Homologues (species, bitscore): IDH2 (Homo sapiens, 545.8); Idh2 (Mus musculus, 548.1); idh1 (Danio rerio, 521.2); idh2 (Xenopus tropicalis, 554.7); Idh (Drosophila melanogaster, 507.7); idh-2 (Caenorhabditis elegans, 539.3); AT5G14590 (Arabidopsis thaliana, 550.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:458694-459932:+ | gene-YLR174W_AKU4011 | rna-NM_001182061.1_AKU4011 | cds-NP_013275.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:15923-17161:+ | gene-YLR174W_BG1 | rna-NM_001182061.1_BG1 | cds-NP_013275.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:499035-500273:+ | gene-YLR174W_Bruggeman | rna-NM_001182061.1_Bruggeman | cds-NP_013275.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:498566-499804:+ | gene-YLR174W_CAT1 | rna-NM_001182061.1_CAT1 | cds-NP_013275.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:494191-495429:+ | gene-YLR174W_CBS1585 | rna-NM_001182061.1_CBS1585 | cds-NP_013275.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:484332-485570:+ | gene-YLR174W_CBS436 | rna-NM_001182061.1_CBS436 | cds-NP_013275.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:462762-464000:+ | gene-YLR174W_CBS6412 | rna-NM_001182061.1_CBS6412 | cds-NP_013275.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:494497-495735:+ | gene-YLR174W_CBS6413 | rna-NM_001182061.1_CBS6413 | cds-NP_013275.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:489308-490546:+ | gene-YLR174W_CENPK1137D | rna-NM_001182061.1_CENPK1137D | cds-NP_013275.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:458215-459453:+ | gene-YLR174W_EthanolRed | rna-NM_001182061.1_EthanolRed | cds-NP_013275.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:487142-488380:+ | gene-YLR174W_FaliES1 | rna-NM_001182061.1_FaliES1 | cds-NP_013275.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:14076-15314:+ | gene-YLR174W_JAY291 | rna-NM_001182061.1_JAY291 | cds-NP_013275.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:499056-500294:+ | gene-YLR174W_MUCL30387 | rna-NM_001182061.1_MUCL30387 | cds-NP_013275.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:503988-505226:+ | gene-YLR174W_MUCL30388 | rna-NM_001182061.1_MUCL30388 | cds-NP_013275.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:495188-496426:+ | gene-YLR174W_MUCL39482 | rna-NM_001182061.1_MUCL39482 | cds-NP_013275.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:495760-496998:+ | gene-YLR174W_MUCL42920 | rna-NM_001182061.1_MUCL42920 | cds-NP_013275.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:504565-505803:+ | gene-YLR174W_NCIM3186 | rna-NM_001182061.1_NCIM3186 | cds-NP_013275.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:487612-488850:+ | gene-YLR174W_NCYC1407 | rna-NM_001182061.1_NCYC1407 | cds-NP_013275.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:491863-493101:+ | gene-YLR174W_PE2H3 | rna-NM_001182061.1_PE2H3 | cds-NP_013275.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:491607-492845:+ | gene-YLR174W_PE2H4 | rna-NM_001182061.1_PE2H4 | cds-NP_013275.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:504591-505829:+ | gene-YLR174W_S288C | rna-NM_001182061.1_S288C | cds-NP_013275.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:14134-15372:+ | gene-YLR174W_SA1 | rna-NM_001182061.1_SA1 | cds-NP_013275.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:489666-490904:+ | gene-YLR174W_ThermosaccDry | rna-NM_001182061.1_ThermosaccDry | cds-NP_013275.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:500976-502214:+ | gene-YLR174W_VR1 | rna-NM_001182061.1_VR1 | cds-NP_013275.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:14035-15273:+ | gene-YLR174W_ZTW1 | rna-NM_001182061.1_ZTW1 | cds-NP_013275.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:475701-476939:+ | gene-YLR174W_Sparadoxus | rna-NM_001182061.1_Sparadoxus | cds-NP_013275.1_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |