IDH2 (YOR136W)


Gene profile

Gene name: IDH2
Reference locus (S288C): YOR136W
Gene biotype: protein_coding

Description: Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase; complex catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated; Belongs to the isocitrate and isopropylmalate dehydrogenases family

Top 10 interactors (score): ACO1 (0.999); IDH1 (0.999); KGD1 (0.998); CIT1 (0.998); IDP1 (0.998); LSC2 (0.998); MDH1 (0.998); CIT2 (0.995); ACO2 (0.995); KGD2 (0.994); FUM1 (0.994); CIT3 (0.993); IDP2 (0.992); LSC1 (0.988); IDP3 (0.988); MDH3 (0.987); MAS1 (0.985); LPD1 (0.984); SES1 (0.962); ATP1 (0.96)

Homologues (species, bitscore): IDH3A (Homo sapiens, 357.8); Idh3a (Mus musculus, 359.8); idh3a (Danio rerio, 357.8); idh3a (Xenopus tropicalis, 357.1); l(1)G0156 (Drosophila melanogaster, 388.3); idha-1 (Caenorhabditis elegans, 383.6); IDH-V (Arabidopsis thaliana, 362.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:583700-584809:+ gene-YOR136W_AKU4011 rna-NM_001183555.1_AKU4011 cds-NP_014779.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000171.1:13841-14950:- gene-YOR136W_BG1 rna-NM_001183555.1_BG1 cds-NP_014779.1_BG1 99.4 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:567859-568968:+ gene-YOR136W_Bruggeman rna-NM_001183555.1_Bruggeman cds-NP_014779.1_Bruggeman 99.2 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:567884-568993:+ gene-YOR136W_CAT1 rna-NM_001183555.1_CAT1 cds-NP_014779.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:559880-560989:+ gene-YOR136W_CBS1585 rna-NM_001183555.1_CBS1585 cds-NP_014779.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:564586-565695:+ gene-YOR136W_CBS436 rna-NM_001183555.1_CBS436 cds-NP_014779.1_CBS436 99.2 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:557369-558478:+ gene-YOR136W_CBS6412 rna-NM_001183555.1_CBS6412 cds-NP_014779.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:566161-567270:+ gene-YOR136W_CBS6413 rna-NM_001183555.1_CBS6413 cds-NP_014779.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:580006-581115:+ gene-YOR136W_CENPK1137D rna-NM_001183555.1_CENPK1137D cds-NP_014779.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:560017-561126:+ gene-YOR136W_EthanolRed rna-NM_001183555.1_EthanolRed cds-NP_014779.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:564870-565979:+ gene-YOR136W_FaliES1 rna-NM_001183555.1_FaliES1 cds-NP_014779.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000070.1:77572-78681:- gene-YOR136W_JAY291 rna-NM_001183555.1_JAY291 cds-NP_014779.1_JAY291 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:572420-573529:+ gene-YOR136W_MUCL30387 rna-NM_001183555.1_MUCL30387 cds-NP_014779.1_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:578500-579609:+ gene-YOR136W_MUCL30388 rna-NM_001183555.1_MUCL30388 cds-NP_014779.1_MUCL30388 99.2 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:567955-569064:+ gene-YOR136W_MUCL39482 rna-NM_001183555.1_MUCL39482 cds-NP_014779.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:583550-584659:+ gene-YOR136W_MUCL42920 rna-NM_001183555.1_MUCL42920 cds-NP_014779.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:580139-581248:+ gene-YOR136W_NCIM3186 rna-NM_001183555.1_NCIM3186 cds-NP_014779.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:574221-575330:+ gene-YOR136W_NCYC1407 rna-NM_001183555.1_NCYC1407 cds-NP_014779.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:572729-573838:+ gene-YOR136W_PE2H3 rna-NM_001183555.1_PE2H3 cds-NP_014779.1_PE2H3 99.4 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:583106-584215:+ gene-YOR136W_PE2H4 rna-NM_001183555.1_PE2H4 cds-NP_014779.1_PE2H4 99.4 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:580250-581359:+ gene-YOR136W_S288C rna-NM_001183555.1_S288C cds-NP_014779.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:2714-3823:+ gene-YOR136W_SA1 rna-NM_001183555.1_SA1 cds-NP_014779.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:564053-565162:+ gene-YOR136W_ThermosaccDry rna-NM_001183555.1_ThermosaccDry cds-NP_014779.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:627726-628835:+ gene-YOR136W_VR1 rna-NM_001183555.1_VR1 cds-NP_014779.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:297498-298607:+ gene-YOR136W_ZTW1 rna-NM_001183555.1_ZTW1 cds-NP_014779.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:568887-569996:+ gene-YOR136W_Sparadoxus rna-NM_001183555.1_Sparadoxus cds-NP_014779.1_Sparadoxus 91.9 100.0 Verified 1 1 1 False True False False False

Additional files