IDH1 (YNL037C)


Gene profile

Gene name: IDH1
Reference locus (S288C): YNL037C
Gene biotype: protein_coding

Description: Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase; complex catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family

Top 10 interactors (score): ACO1 (0.999); CIT1 (0.999); LSC1 (0.999); IDH2 (0.999); IDP1 (0.998); KGD1 (0.998); ATP2 (0.996); ACO2 (0.995); IDP2 (0.992); LPD1 (0.99); KGD2 (0.988); IDP3 (0.986); CIT2 (0.981); MAS1 (0.98); MDH1 (0.979); SEC4 (0.978); SDH2 (0.976); LYS12 (0.975); ATP1 (0.974); CYT1 (0.973)

Homologues (species, bitscore): IDH3G (Homo sapiens, 347.1); Idh3g (Mus musculus, 347.1); zgc:113076 (Danio rerio, 347.8); idh3g (Xenopus tropicalis, 336.7); CG6439 (Drosophila melanogaster, 337.8); idhg-1 (Caenorhabditis elegans, 344.7); IDH-V (Arabidopsis thaliana, 320.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:545379-546461:- gene-YNL037C_AKU4011 rna-NM_001182876.1_AKU4011 cds-NP_014361.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:449328-450410:- gene-YNL037C_BG1 rna-NM_001182876.1_BG1 cds-NP_014361.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:563531-564613:- gene-YNL037C_Bruggeman rna-NM_001182876.1_Bruggeman cds-NP_014361.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:599060-600142:- gene-YNL037C_CAT1 rna-NM_001182876.1_CAT1 cds-NP_014361.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:546049-547131:- gene-YNL037C_CBS1585 rna-NM_001182876.1_CBS1585 cds-NP_014361.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:614288-615370:- gene-YNL037C_CBS436 rna-NM_001182876.1_CBS436 cds-NP_014361.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:541142-542224:- gene-YNL037C_CBS6412 rna-NM_001182876.1_CBS6412 cds-NP_014361.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:542460-543542:- gene-YNL037C_CBS6413 rna-NM_001182876.1_CBS6413 cds-NP_014361.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:551506-552588:- gene-YNL037C_CENPK1137D rna-NM_001182876.1_CENPK1137D cds-NP_014361.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:548192-549274:- gene-YNL037C_EthanolRed rna-NM_001182876.1_EthanolRed cds-NP_014361.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:538975-540057:- gene-YNL037C_FaliES1 rna-NM_001182876.1_FaliES1 cds-NP_014361.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000040.1:53760-54842:- gene-YNL037C_JAY291 rna-NM_001182876.1_JAY291 cds-NP_014361.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:559745-560827:- gene-YNL037C_MUCL30387 rna-NM_001182876.1_MUCL30387 cds-NP_014361.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:588504-589586:- gene-YNL037C_MUCL30388 rna-NM_001182876.1_MUCL30388 cds-NP_014361.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:543466-544548:- gene-YNL037C_MUCL39482 rna-NM_001182876.1_MUCL39482 cds-NP_014361.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:547531-548613:- gene-YNL037C_MUCL42920 rna-NM_001182876.1_MUCL42920 cds-NP_014361.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:557889-558971:- gene-YNL037C_NCIM3186 rna-NM_001182876.1_NCIM3186 cds-NP_014361.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:545517-546599:- gene-YNL037C_NCYC1407 rna-NM_001182876.1_NCYC1407 cds-NP_014361.1_NCYC1407 99.5 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:548677-549759:- gene-YNL037C_PE2H3 rna-NM_001182876.1_PE2H3 cds-NP_014361.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:543753-544835:- gene-YNL037C_PE2H4 rna-NM_001182876.1_PE2H4 cds-NP_014361.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:557920-559002:- gene-YNL037C_S288C rna-NM_001182876.1_S288C cds-NP_014361.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:136602-137684:- gene-YNL037C_SA1 rna-NM_001182876.1_SA1 cds-NP_014361.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:539601-540683:- gene-YNL037C_ThermosaccDry rna-NM_001182876.1_ThermosaccDry cds-NP_014361.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:558638-559720:- gene-YNL037C_VR1 rna-NM_001182876.1_VR1 cds-NP_014361.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:448921-450003:- gene-YNL037C_ZTW1 rna-NM_001182876.1_ZTW1 cds-NP_014361.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:554568-555650:- gene-YNL037C_Sparadoxus rna-NM_001182876.1_Sparadoxus cds-NP_014361.1_Sparadoxus 92.6 100.0 Verified 1 1 1 False True False False False

Additional files