Gene name: ICT1
Reference locus (S288C): YLR099C
Gene biotype: protein_coding
Description: 1-acylglycerol-3-phosphate O-acyltransferase ICT1; Lysophosphatidic acid acyltransferase; responsible for enhanced phospholipid synthesis during organic solvent stress; null displays increased sensitivity to Calcofluor white; highly expressed during organic solvent stress; ICT1 has a paralog, ECM18, that arose from the whole genome duplication; human ABHD5 can complement ict1 null mutant; Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily
Top 10 interactors (score): ALE1 (0.761); LOA1 (0.746); GRE2 (0.717); YOR1 (0.638); YGR035C (0.62); PRY3 (0.611); SNQ2 (0.583); PDR16 (0.572); PTH4 (0.565); YLR126C (0.563); PUF6 (0.558); AYR1 (0.554); YJU3 (0.547); PGC1 (0.536); DGA1 (0.536); PDR15 (0.535); ECT1 (0.53); GPT2 (0.508); FMP30 (0.505); SDD3 (0.5)
Homologues (species, bitscore): ABHD4 (Homo sapiens, 88.6); Abhd5 (Mus musculus, 90.1); abhd4 (Danio rerio, 109.8); abhd4 (Xenopus tropicalis, 96.7); CG1882 (Drosophila melanogaster, 80.1); C37H5.3 (Caenorhabditis elegans, 102.4); AT4G24160 (Arabidopsis thaliana, 114.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:322237-323421:- | gene-YLR099C_AKU4011 | rna-NM_001181986.1_AKU4011 | cds-NP_013200.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:285420-286604:- | gene-YLR099C_BG1 | rna-NM_001181986.1_BG1 | cds-NP_013200.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:332091-333275:- | gene-YLR099C_Bruggeman | rna-NM_001181986.1_Bruggeman | cds-NP_013200.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:332441-333625:- | gene-YLR099C_CAT1 | rna-NM_001181986.1_CAT1 | cds-NP_013200.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:329379-330563:- | gene-YLR099C_CBS1585 | rna-NM_001181986.1_CBS1585 | cds-NP_013200.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:319952-321136:- | gene-YLR099C_CBS436 | rna-NM_001181986.1_CBS436 | cds-NP_013200.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:327798-328982:- | gene-YLR099C_CBS6412 | rna-NM_001181986.1_CBS6412 | cds-NP_013200.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:329645-330829:- | gene-YLR099C_CBS6413 | rna-NM_001181986.1_CBS6413 | cds-NP_013200.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:324768-325952:- | gene-YLR099C_CENPK1137D | rna-NM_001181986.1_CENPK1137D | cds-NP_013200.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:321796-322980:- | gene-YLR099C_EthanolRed | rna-NM_001181986.1_EthanolRed | cds-NP_013200.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:321615-322799:- | gene-YLR099C_FaliES1 | rna-NM_001181986.1_FaliES1 | cds-NP_013200.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000129.1:96553-97737:- | gene-YLR099C_JAY291 | rna-NM_001181986.1_JAY291 | cds-NP_013200.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:329470-330654:- | gene-YLR099C_MUCL30387 | rna-NM_001181986.1_MUCL30387 | cds-NP_013200.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:337135-338319:- | gene-YLR099C_MUCL30388 | rna-NM_001181986.1_MUCL30388 | cds-NP_013200.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:329887-331071:- | gene-YLR099C_MUCL39482 | rna-NM_001181986.1_MUCL39482 | cds-NP_013200.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:329791-330975:- | gene-YLR099C_MUCL42920 | rna-NM_001181986.1_MUCL42920 | cds-NP_013200.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:339718-340902:- | gene-YLR099C_NCIM3186 | rna-NM_001181986.1_NCIM3186 | cds-NP_013200.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:321950-323134:- | gene-YLR099C_NCYC1407 | rna-NM_001181986.1_NCYC1407 | cds-NP_013200.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:327718-328902:- | gene-YLR099C_PE2H3 | rna-NM_001181986.1_PE2H3 | cds-NP_013200.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:327459-328643:- | gene-YLR099C_PE2H4 | rna-NM_001181986.1_PE2H4 | cds-NP_013200.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:339744-340928:- | gene-YLR099C_S288C | rna-NM_001181986.1_S288C | cds-NP_013200.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000033.1:33173-34357:+ | gene-YLR099C_SA1 | rna-NM_001181986.1_SA1 | cds-NP_013200.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:321788-322972:- | gene-YLR099C_ThermosaccDry | rna-NM_001181986.1_ThermosaccDry | cds-NP_013200.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:335959-337143:- | gene-YLR099C_VR1 | rna-NM_001181986.1_VR1 | cds-NP_013200.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:321215-322399:- | gene-YLR099C_ZTW1 | rna-NM_001181986.1_ZTW1 | cds-NP_013200.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:330016-331200:- | gene-YLR099C_Sparadoxus | rna-NM_001181986.1_Sparadoxus | cds-NP_013200.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |