Gene name: ICL1
Reference locus (S288C): YER065C
Gene biotype: protein_coding
Description: Isocitrate lyase; catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose
Top 10 interactors (score): MLS1 (0.999); DAL7 (0.997); PCK1 (0.996); FBP1 (0.994); ACO1 (0.993); AGX1 (0.982); IDP2 (0.982); ACO2 (0.98); YAT2 (0.977); ACS1 (0.974); GOR1 (0.972); SFC1 (0.969); MDH2 (0.943); CIT3 (0.94); CIT2 (0.936); CIT1 (0.929); CAT2 (0.919); FOX2 (0.902); VID24 (0.894); LSC1 (0.886)
Homologues (species, bitscore): icl-1 (Caenorhabditis elegans, 259.2); ICL (Arabidopsis thaliana, 580.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:279029-280702:- | gene-YER065C_AKU4011 | rna-NM_001178956.3_AKU4011 | cds-NP_010987.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:145087-146760:+ | gene-YER065C_BG1 | rna-NM_001178956.3_BG1 | cds-NP_010987.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:288327-290000:- | gene-YER065C_Bruggeman | rna-NM_001178956.3_Bruggeman | cds-NP_010987.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:281971-283644:- | gene-YER065C_CAT1 | rna-NM_001178956.3_CAT1 | cds-NP_010987.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:278883-280556:- | gene-YER065C_CBS1585 | rna-NM_001178956.3_CBS1585 | cds-NP_010987.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:280782-282455:- | gene-YER065C_CBS436 | rna-NM_001178956.3_CBS436 | cds-NP_010987.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:278351-280024:- | gene-YER065C_CBS6412 | rna-NM_001178956.3_CBS6412 | cds-NP_010987.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:284361-286034:- | gene-YER065C_CBS6413 | rna-NM_001178956.3_CBS6413 | cds-NP_010987.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:283074-284747:- | gene-YER065C_CENPK1137D | rna-NM_001178956.3_CENPK1137D | cds-NP_010987.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:279367-281040:- | gene-YER065C_EthanolRed | rna-NM_001178956.3_EthanolRed | cds-NP_010987.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:279820-281493:- | gene-YER065C_FaliES1 | rna-NM_001178956.3_FaliES1 | cds-NP_010987.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000254.1:7228-8901:- | gene-YER065C_JAY291 | rna-NM_001178956.3_JAY291 | cds-NP_010987.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:283765-285438:- | gene-YER065C_MUCL30387 | rna-NM_001178956.3_MUCL30387 | cds-NP_010987.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:279434-281107:- | gene-YER065C_MUCL30388 | rna-NM_001178956.3_MUCL30388 | cds-NP_010987.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:277919-279592:- | gene-YER065C_MUCL39482 | rna-NM_001178956.3_MUCL39482 | cds-NP_010987.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:284962-286635:- | gene-YER065C_MUCL42920 | rna-NM_001178956.3_MUCL42920 | cds-NP_010987.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:285240-286913:- | gene-YER065C_NCIM3186 | rna-NM_001178956.3_NCIM3186 | cds-NP_010987.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:282983-284656:- | gene-YER065C_NCYC1407 | rna-NM_001178956.3_NCYC1407 | cds-NP_010987.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:293623-295296:- | gene-YER065C_PE2H3 | rna-NM_001178956.3_PE2H3 | cds-NP_010987.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:283564-285237:- | gene-YER065C_PE2H4 | rna-NM_001178956.3_PE2H4 | cds-NP_010987.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:285241-286914:- | gene-YER065C_S288C | rna-NM_001178956.3_S288C | cds-NP_010987.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000059.1:71740-73413:- | gene-YER065C_SA1 | rna-NM_001178956.3_SA1 | cds-NP_010987.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:280616-282289:- | gene-YER065C_ThermosaccDry | rna-NM_001178956.3_ThermosaccDry | cds-NP_010987.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:280306-281979:- | gene-YER065C_VR1 | rna-NM_001178956.3_VR1 | cds-NP_010987.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:277785-279458:- | gene-YER065C_ZTW1 | rna-NM_001178956.3_ZTW1 | cds-NP_010987.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:281708-283381:- | gene-YER065C_Sparadoxus | rna-NM_001178956.3_Sparadoxus | cds-NP_010987.3_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |