ICE2 (YIL090W)


Gene profile

Gene name: ICE2
Reference locus (S288C): YIL090W
Gene biotype: protein_coding

Description: Protein ICE2; Integral ER membrane protein with type-III transmembrane domains; required for maintenance of ER zinc homeostasis; necessary for efficient targeting of Trm1p tRNA methyltransferase to inner nuclear membrane; mutations cause defects in cortical ER morphology in both the mother and daughter cells

Top 10 interactors (score): DGK1 (0.999); SCS2 (0.923); SEY1 (0.827); SCS3 (0.825); OPI3 (0.815); TRM1 (0.811); NEM1 (0.772); RTN1 (0.727); AIM19 (0.72); DGA1 (0.718); YOP1 (0.702); SEI1 (0.68); TCB1 (0.674); CHO2 (0.641); EMC5 (0.63); YIL060W (0.618); FSH3 (0.61); CLA4 (0.596); IST2 (0.584); TCB2 (0.574)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:195015-196490:+ gene-YIL090W_AKU4011 rna-NM_001179438.1_AKU4011 cds-NP_012176.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:58008-59483:+ gene-YIL090W_BG1 rna-NM_001179438.1_BG1 cds-NP_012176.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:199727-201202:+ gene-YIL090W_Bruggeman rna-NM_001179438.1_Bruggeman cds-NP_012176.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:191760-193235:+ gene-YIL090W_CAT1 rna-NM_001179438.1_CAT1 cds-NP_012176.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:195272-196747:+ gene-YIL090W_CBS1585 rna-NM_001179438.1_CBS1585 cds-NP_012176.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:186265-187740:+ gene-YIL090W_CBS436 rna-NM_001179438.1_CBS436 cds-NP_012176.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:192652-194127:+ gene-YIL090W_CBS6412 rna-NM_001179438.1_CBS6412 cds-NP_012176.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:186304-187779:+ gene-YIL090W_CBS6413 rna-NM_001179438.1_CBS6413 cds-NP_012176.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:185306-186781:+ gene-YIL090W_CENPK1137D rna-NM_001179438.1_CENPK1137D cds-NP_012176.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:180237-181712:+ gene-YIL090W_EthanolRed rna-NM_001179438.1_EthanolRed cds-NP_012176.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:196232-197707:+ gene-YIL090W_FaliES1 rna-NM_001179438.1_FaliES1 cds-NP_012176.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000025.1:30754-32229:- gene-YIL090W_JAY291 rna-NM_001179438.1_JAY291 cds-NP_012176.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:197439-198914:+ gene-YIL090W_MUCL30387 rna-NM_001179438.1_MUCL30387 cds-NP_012176.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:195236-196711:+ gene-YIL090W_MUCL30388 rna-NM_001179438.1_MUCL30388 cds-NP_012176.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:196119-197594:+ gene-YIL090W_MUCL39482 rna-NM_001179438.1_MUCL39482 cds-NP_012176.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:199380-200855:+ gene-YIL090W_MUCL42920 rna-NM_001179438.1_MUCL42920 cds-NP_012176.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:193595-195070:+ gene-YIL090W_NCIM3186 rna-NM_001179438.1_NCIM3186 cds-NP_012176.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:200162-201637:+ gene-YIL090W_NCYC1407 rna-NM_001179438.1_NCYC1407 cds-NP_012176.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:194754-196229:+ gene-YIL090W_PE2H3 rna-NM_001179438.1_PE2H3 cds-NP_012176.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:188705-190180:+ gene-YIL090W_PE2H4 rna-NM_001179438.1_PE2H4 cds-NP_012176.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:193595-195070:+ gene-YIL090W_S288C rna-NM_001179438.1_S288C cds-NP_012176.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000111.1:10201-11676:- gene-YIL090W_SA1 rna-NM_001179438.1_SA1 cds-NP_012176.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:194899-196374:+ gene-YIL090W_ThermosaccDry rna-NM_001179438.1_ThermosaccDry cds-NP_012176.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:192567-194042:+ gene-YIL090W_VR1 rna-NM_001179438.1_VR1 cds-NP_012176.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:169833-171308:+ gene-YIL090W_ZTW1 rna-NM_001179438.1_ZTW1 cds-NP_012176.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:193838-195313:+ gene-YIL090W_Sparadoxus rna-NM_001179438.1_Sparadoxus cds-NP_012176.1_Sparadoxus 92.6 100.0 Verified 1 1 1 False True False False False

Additional files