Gene name: HYR1
Reference locus (S288C): YIR037W
Gene biotype: protein_coding
Description: Glutathione peroxidase-like peroxiredoxin HYR1; Thiol peroxidase; functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor; HYR1 has a paralog, GPX1, that arose from the whole genome duplication
Top 10 interactors (score): YAP1 (0.981); YBP1 (0.964); TSA1 (0.958); GTT1 (0.954); GRX2 (0.952); AHP1 (0.939); PRX1 (0.939); GLR1 (0.926); TRX2 (0.902); CTA1 (0.902); CTT1 (0.901); TSA2 (0.899); GRX1 (0.894); TRX1 (0.887); TRR1 (0.883); SOD2 (0.882); TRX3 (0.864); MXR2 (0.853); SOD1 (0.851); URE2 (0.83)
Homologues (species, bitscore): GPX4 (Homo sapiens, 117.9); Gpx4 (Mus musculus, 118.2); gpx7 (Danio rerio, 116.7); gpx7 (Xenopus tropicalis, 110.2); PHGPx (Drosophila melanogaster, 135.6); R05H10.5 (Caenorhabditis elegans, 133.3); GPX6 (Arabidopsis thaliana, 165.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:421357-421848:+ | gene-YIR037W_AKU4011 | rna-NM_001179559.1_AKU4011 | cds-NP_012303.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000072.1:4986-5477:- | gene-YIR037W_BG1 | rna-NM_001179559.1_BG1 | cds-NP_012303.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:427551-428042:+ | gene-YIR037W_Bruggeman | rna-NM_001179559.1_Bruggeman | cds-NP_012303.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:412508-412999:+ | gene-YIR037W_CAT1 | rna-NM_001179559.1_CAT1 | cds-NP_012303.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:422312-422803:+ | gene-YIR037W_CBS1585 | rna-NM_001179559.1_CBS1585 | cds-NP_012303.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:414282-414773:+ | gene-YIR037W_CBS436 | rna-NM_001179559.1_CBS436 | cds-NP_012303.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:120815-121306:+ | gene-YIR037W_CBS6412 | rna-NM_001179559.1_CBS6412 | cds-NP_012303.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:413413-413904:+ | gene-YIR037W_CBS6413 | rna-NM_001179559.1_CBS6413 | cds-NP_012303.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:414787-415278:+ | gene-YIR037W_CENPK1137D | rna-NM_001179559.1_CENPK1137D | cds-NP_012303.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:404274-404765:+ | gene-YIR037W_EthanolRed | rna-NM_001179559.1_EthanolRed | cds-NP_012303.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:424102-424593:+ | gene-YIR037W_FaliES1 | rna-NM_001179559.1_FaliES1 | cds-NP_012303.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000039.1:9505-9996:- | gene-YIR037W_JAY291 | rna-NM_001179559.1_JAY291 | cds-NP_012303.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:428304-428795:+ | gene-YIR037W_MUCL30387 | rna-NM_001179559.1_MUCL30387 | cds-NP_012303.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:422923-423414:+ | gene-YIR037W_MUCL30388 | rna-NM_001179559.1_MUCL30388 | cds-NP_012303.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:422459-422950:+ | gene-YIR037W_MUCL39482 | rna-NM_001179559.1_MUCL39482 | cds-NP_012303.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:428766-429257:+ | gene-YIR037W_MUCL42920 | rna-NM_001179559.1_MUCL42920 | cds-NP_012303.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:423128-423619:+ | gene-YIR037W_NCIM3186 | rna-NM_001179559.1_NCIM3186 | cds-NP_012303.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:426220-426711:+ | gene-YIR037W_NCYC1407 | rna-NM_001179559.1_NCYC1407 | cds-NP_012303.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:417140-417631:+ | gene-YIR037W_PE2H3 | rna-NM_001179559.1_PE2H3 | cds-NP_012303.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:411846-412337:+ | gene-YIR037W_PE2H4 | rna-NM_001179559.1_PE2H4 | cds-NP_012303.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:423128-423619:+ | gene-YIR037W_S288C | rna-NM_001179559.1_S288C | cds-NP_012303.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000097.1:5229-5720:- | gene-YIR037W_SA1 | rna-NM_001179559.1_SA1 | cds-NP_012303.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:420967-421458:+ | gene-YIR037W_ThermosaccDry | rna-NM_001179559.1_ThermosaccDry | cds-NP_012303.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:418377-418868:+ | gene-YIR037W_VR1 | rna-NM_001179559.1_VR1 | cds-NP_012303.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000020.1:30212-30703:+ | gene-YIR037W_ZTW1 | rna-NM_001179559.1_ZTW1 | cds-NP_012303.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:418676-419167:+ | gene-YIR037W_Sparadoxus | rna-NM_001179559.1_Sparadoxus | cds-NP_012303.1_Sparadoxus | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |