HYM1 (YKL189W)


Gene profile

Gene name: HYM1
Reference locus (S288C): YKL189W
Gene biotype: protein_coding

Description: Calcium binding protein 39; Protein HYM1; Component of the RAM signaling network; is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response; Belongs to the Mo25 family

Top 10 interactors (score): KIC1 (0.999); SOG2 (0.999); CBK1 (0.997); MOB2 (0.997); TAO3 (0.996); SPS1 (0.957); ACE2 (0.921); UFD4 (0.918); SWI5 (0.79); MRPL31 (0.779); SNF1 (0.776); DIG2 (0.656); YHR131C (0.651); ATG17 (0.645); DIG1 (0.645); NUD1 (0.632); PRR1 (0.607); SKS1 (0.589); DIB1 (0.57); MRX12 (0.57)

Homologues (species, bitscore): CAB39 (Homo sapiens, 206.1); Cab39 (Mus musculus, 206.5); cab39 (Danio rerio, 201.4); cab39 (Xenopus tropicalis, 203.0); Mo25 (Drosophila melanogaster, 188.0); mop-25.2 (Caenorhabditis elegans, 191.4); AT4G17270 (Arabidopsis thaliana, 161.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:71554-72753:+ gene-YKL189W_AKU4011 rna-NM_001179755.1_AKU4011 cds-NP_012732.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:48080-49279:+ gene-YKL189W_BG1 rna-NM_001179755.1_BG1 cds-NP_012732.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:88939-90138:+ gene-YKL189W_Bruggeman rna-NM_001179755.1_Bruggeman cds-NP_012732.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:83899-85098:+ gene-YKL189W_CAT1 rna-NM_001179755.1_CAT1 cds-NP_012732.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:83536-84735:+ gene-YKL189W_CBS1585 rna-NM_001179755.1_CBS1585 cds-NP_012732.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:82293-83492:+ gene-YKL189W_CBS436 rna-NM_001179755.1_CBS436 cds-NP_012732.1_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:69127-70326:+ gene-YKL189W_CBS6412 rna-NM_001179755.1_CBS6412 cds-NP_012732.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:84255-85454:+ gene-YKL189W_CBS6413 rna-NM_001179755.1_CBS6413 cds-NP_012732.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:84531-85730:+ gene-YKL189W_CENPK1137D rna-NM_001179755.1_CENPK1137D cds-NP_012732.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:82441-83640:+ gene-YKL189W_EthanolRed rna-NM_001179755.1_EthanolRed cds-NP_012732.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:83142-84341:+ gene-YKL189W_FaliES1 rna-NM_001179755.1_FaliES1 cds-NP_012732.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:82125-83324:+ gene-YKL189W_JAY291 rna-NM_001179755.1_JAY291 cds-NP_012732.1_JAY291 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:91240-92439:+ gene-YKL189W_MUCL30387 rna-NM_001179755.1_MUCL30387 cds-NP_012732.1_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:85585-86784:+ gene-YKL189W_MUCL30388 rna-NM_001179755.1_MUCL30388 cds-NP_012732.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:83593-84792:+ gene-YKL189W_MUCL39482 rna-NM_001179755.1_MUCL39482 cds-NP_012732.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:87926-89125:+ gene-YKL189W_MUCL42920 rna-NM_001179755.1_MUCL42920 cds-NP_012732.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:84693-85892:+ gene-YKL189W_NCIM3186 rna-NM_001179755.1_NCIM3186 cds-NP_012732.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:83617-84816:+ gene-YKL189W_NCYC1407 rna-NM_001179755.1_NCYC1407 cds-NP_012732.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:90667-91866:+ gene-YKL189W_PE2H3 rna-NM_001179755.1_PE2H3 cds-NP_012732.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:86961-88160:+ gene-YKL189W_PE2H4 rna-NM_001179755.1_PE2H4 cds-NP_012732.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:84704-85903:+ gene-YKL189W_S288C rna-NM_001179755.1_S288C cds-NP_012732.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:906-2105:+ gene-YKL189W_SA1 rna-NM_001179755.1_SA1 cds-NP_012732.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:83842-85041:+ gene-YKL189W_ThermosaccDry rna-NM_001179755.1_ThermosaccDry cds-NP_012732.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:82372-83571:+ gene-YKL189W_VR1 rna-NM_001179755.1_VR1 cds-NP_012732.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:82245-83444:+ gene-YKL189W_ZTW1 rna-NM_001179755.1_ZTW1 cds-NP_012732.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:96819-98018:+ gene-YKL189W_Sparadoxus rna-NM_001179755.1_Sparadoxus cds-NP_012732.1_Sparadoxus 91.1 99.9 Verified 1 1 1 False True False False False

Additional files