Gene name: HXT17
Reference locus (S288C): YNR072W
Gene biotype: protein_coding
Description: Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT17; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose; HXT17 has a paralog, HXT13, that arose from a segmental duplication
Top 10 interactors (score): YIL174W (0.744); SNF1 (0.724); MAN2 (0.621); RGT1 (0.617); YNR071C (0.572); ARR3 (0.485); YHR213W (0.453); STD1 (0.452); SUC2 (0.444)
Homologues (species, bitscore): SLC2A4 (Homo sapiens, 160.2); Slc2a2 (Mus musculus, 163.3); slc2a3b (Danio rerio, 167.2); slc2a3 (Xenopus tropicalis, 170.6); Glut1 (Drosophila melanogaster, 157.9); hmit-1.3 (Caenorhabditis elegans, 168.7); STP1 (Arabidopsis thaliana, 206.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | MBVY01000115.1:1-1196:- | gene-YNR072W_Bruggeman | rna-NM_001183249.1_Bruggeman | cds-NP_014470.1_Bruggeman | 68.2 | 69.6 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:810813-812507:+ | gene-YNR072W_CAT1 | rna-NM_001183249.1_CAT1 | cds-NP_014470.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:824410-826131:+ | gene-YNR072W_CBS436 | rna-NM_001183249.1_CBS436 | cds-NP_014470.1_CBS436 | 98.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000427.1:40413-42098:+ | gene-YNR072W_JAY291 | rna-NM_001183249.1_JAY291 | cds-NP_014470.1_JAY291 | 98.1 | 99.4 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | MBVX01000004.1:2512-4206:+ | gene-YNR072W_MUCL30387 | rna-NM_001183249.1_MUCL30387 | cds-NP_014470.1_MUCL30387 | 97.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | MBVW01000032.1:1749-2751:- | gene-YNR072W_MUCL30388 | rna-NM_001183249.1_MUCL30388 | cds-NP_014470.1_MUCL30388 | 58.8 | 59.1 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:772626-774320:+ | gene-YNR072W_NCIM3186 | rna-NM_001183249.1_NCIM3186 | cds-NP_014470.1_NCIM3186 | 70.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:20355-22049:- | gene-YNR072W_NCYC1407 | rna-NM_001183249.1_NCYC1407 | cds-NP_014470.1_NCYC1407 | 97.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:757096-758790:+ | gene-YNR072W_PE2H3 | rna-NM_001183249.1_PE2H3 | cds-NP_014470.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:758484-760178:+ | gene-YNR072W_PE2H4 | rna-NM_001183249.1_PE2H4 | cds-NP_014470.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:772657-774351:+ | gene-YNR072W_S288C | rna-NM_001183249.1_S288C | cds-NP_014470.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000225.1:1-779:+ | gene-YNR072W_SA1 | rna-NM_001183249.1_SA1 | cds-NP_014470.1_SA1 | 45.9 | 45.9 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:791985-793679:+ | gene-YNR072W_VR1 | rna-NM_001183249.1_VR1 | cds-NP_014470.1_VR1 | 59.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:658496-660190:+ | gene-YNR072W_ZTW1 | rna-NM_001183249.1_ZTW1 | cds-NP_014470.1_ZTW1 | 97.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:762676-764370:+ | gene-YNR072W_Sparadoxus | rna-NM_001183249.1_Sparadoxus | cds-NP_014470.1_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |