HXT15 (YDL245C)


Gene profile

Gene name: HXT15
Reference locus (S288C): YDL245C
Gene biotype: protein_coding

Description: Mfs transporter, sp family, sugar:h+ symporter; Hexose transporter HXT15; Putative transmembrane polyol transporter; supports growth on and uptake of mannitol, sorbitol and xylitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; similarity to hexose transporters; expression is induced by low levels of glucose and repressed by high levels of glucose

Top 10 interactors (score): HXT16 (0.874); SOR2 (0.797); SOR1 (0.736); SNF1 (0.663); YDL247W-A (0.65); HXT13 (0.615); YAL059C-A (0.614); YAL056C-A (0.614); COS7 (0.614); MAN2 (0.563); DSF1 (0.538); FIT1 (0.499); MPH2 (0.485); YHR213W (0.454); BDH2 (0.45); MPH3 (0.415)

Homologues (species, bitscore): SLC2A3 (Homo sapiens, 154.1); Slc2a2 (Mus musculus, 157.9); slc2a3b (Danio rerio, 156.0); slc2a3 (Xenopus tropicalis, 167.9); Glut1 (Drosophila melanogaster, 151.8); fgt-1 (Caenorhabditis elegans, 162.5); STP1 (Arabidopsis thaliana, 203.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:9867-11570:- gene-YDL245C_Bruggeman rna-NM_001180305.1_Bruggeman cds-NP_010036.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:724838-726541:+ gene-YDL245C_CAT1 rna-NM_001180305.1_CAT1 cds-NP_010036.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:10713-12416:- gene-YDL245C_CBS436 rna-NM_001180305.1_CBS436 cds-NP_010036.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:10605-12308:- gene-YDL245C_CENPK1137D rna-NM_001180305.1_CENPK1137D cds-NP_010036.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:9034-10736:- gene-YDL245C_EthanolRed rna-NM_001180305.1_EthanolRed cds-NP_010036.1_EthanolRed 98.7 99.9 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:721818-723520:+ gene-YDL245C_FaliES1 rna-NM_001180305.1_FaliES1 cds-NP_010036.1_FaliES1 98.7 99.9 Verified 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:9792-11495:- gene-YDL245C_MUCL30387 rna-NM_001180305.1_MUCL30387 cds-NP_010036.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1-1061:- gene-YDL245C_MUCL30388 rna-NM_001180305.1_MUCL30388 cds-NP_010036.1_MUCL30388 62.0 62.2 Verified 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:9744-11447:- gene-YDL245C_MUCL42920 rna-NM_001180305.1_MUCL42920 cds-NP_010036.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:11580-13283:- gene-YDL245C_NCIM3186 rna-NM_001180305.1_NCIM3186 cds-NP_010036.1_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:11657-13360:- gene-YDL245C_S288C rna-NM_001180305.1_S288C cds-NP_010036.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:715516-717218:+ gene-YDL245C_ThermosaccDry rna-NM_001180305.1_ThermosaccDry cds-NP_010036.1_ThermosaccDry 98.7 99.9 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America MBVZ01000183.1:396-1322:- gene-YDL245C_VR1 rna-NM_001180305.1_VR1 cds-NP_010036.1_VR1 50.8 54.4 Mismatch 1 1 0 False False True False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:10867-12569:- gene-YDL245C_ZTW1 rna-NM_001180305.1_ZTW1 cds-NP_010036.1_ZTW1 98.7 99.9 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:13375-15078:- gene-YDL245C_Sparadoxus rna-NM_001180305.1_Sparadoxus cds-NP_010036.1_Sparadoxus 85.5 99.7 Verified 1 1 1 False True False False False

Additional files