Gene name: HXK1
Reference locus (S288C): YFR053C
Gene biotype: protein_coding
Description: Hexokinase-1; Hexokinase isoenzyme 1; a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves hexokinase Hxk2p; HXK1 has a paralog, HXK2, that arose from the whole genome duplication
Top 10 interactors (score): HXK2 (0.999); GLK1 (0.999); PGM2 (0.995); PGI1 (0.989); EMI2 (0.988); SUC2 (0.983); GPH1 (0.982); FBP1 (0.982); NTH1 (0.981); HXT7 (0.971); GSY2 (0.969); YLR446W (0.968); GSY1 (0.968); GLC3 (0.968); ZWF1 (0.964); FBA1 (0.957); NTH2 (0.956); PFK1 (0.952); ALD4 (0.947); GAL10 (0.947)
Homologues (species, bitscore): GCK (Homo sapiens, 273.9); Gck (Mus musculus, 275.8); hk2 (Danio rerio, 272.3); Hkdc1 (Xenopus tropicalis, 285.8); Hex-t2 (Drosophila melanogaster, 283.1); F14B4.2 (Caenorhabditis elegans, 261.5); HXK1 (Arabidopsis thaliana, 259.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:243742-245199:- | gene-YFR053C_AKU4011 | rna-NM_001180018.3_AKU4011 | cds-NP_116711.3_AKU4011 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000071.1:15810-17267:+ | gene-YFR053C_BG1 | rna-NM_001180018.3_BG1 | cds-NP_116711.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:247394-248851:- | gene-YFR053C_Bruggeman | rna-NM_001180018.3_Bruggeman | cds-NP_116711.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:249368-250825:- | gene-YFR053C_CAT1 | rna-NM_001180018.3_CAT1 | cds-NP_116711.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:245242-246699:- | gene-YFR053C_CBS1585 | rna-NM_001180018.3_CBS1585 | cds-NP_116711.3_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:218203-219660:- | gene-YFR053C_CBS436 | rna-NM_001180018.3_CBS436 | cds-NP_116711.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:244316-245773:- | gene-YFR053C_CBS6412 | rna-NM_001180018.3_CBS6412 | cds-NP_116711.3_CBS6412 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:246990-248447:- | gene-YFR053C_CBS6413 | rna-NM_001180018.3_CBS6413 | cds-NP_116711.3_CBS6413 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:249679-251136:- | gene-YFR053C_CENPK1137D | rna-NM_001180018.3_CENPK1137D | cds-NP_116711.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:242865-244322:- | gene-YFR053C_EthanolRed | rna-NM_001180018.3_EthanolRed | cds-NP_116711.3_EthanolRed | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:244515-245972:- | gene-YFR053C_FaliES1 | rna-NM_001180018.3_FaliES1 | cds-NP_116711.3_FaliES1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000453.1:47641-49098:- | gene-YFR053C_JAY291 | rna-NM_001180018.3_JAY291 | cds-NP_116711.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:247842-249299:- | gene-YFR053C_MUCL30387 | rna-NM_001180018.3_MUCL30387 | cds-NP_116711.3_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:243323-244780:- | gene-YFR053C_MUCL30388 | rna-NM_001180018.3_MUCL30388 | cds-NP_116711.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:243164-244621:- | gene-YFR053C_MUCL39482 | rna-NM_001180018.3_MUCL39482 | cds-NP_116711.3_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:242762-244219:- | gene-YFR053C_MUCL42920 | rna-NM_001180018.3_MUCL42920 | cds-NP_116711.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:253591-255048:- | gene-YFR053C_NCIM3186 | rna-NM_001180018.3_NCIM3186 | cds-NP_116711.3_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:244014-245471:- | gene-YFR053C_NCYC1407 | rna-NM_001180018.3_NCYC1407 | cds-NP_116711.3_NCYC1407 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:286051-287508:- | gene-YFR053C_PE2H3 | rna-NM_001180018.3_PE2H3 | cds-NP_116711.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:285599-287056:- | gene-YFR053C_PE2H4 | rna-NM_001180018.3_PE2H4 | cds-NP_116711.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:253592-255049:- | gene-YFR053C_S288C | rna-NM_001180018.3_S288C | cds-NP_116711.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000086.1:16053-17510:+ | gene-YFR053C_SA1 | rna-NM_001180018.3_SA1 | cds-NP_116711.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:243684-245141:- | gene-YFR053C_ThermosaccDry | rna-NM_001180018.3_ThermosaccDry | cds-NP_116711.3_ThermosaccDry | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:259435-260892:- | gene-YFR053C_VR1 | rna-NM_001180018.3_VR1 | cds-NP_116711.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:174126-175583:- | gene-YFR053C_ZTW1 | rna-NM_001180018.3_ZTW1 | cds-NP_116711.3_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:267160-268617:- | gene-YFR053C_Sparadoxus | rna-NM_001180018.3_Sparadoxus | cds-NP_116711.3_Sparadoxus | 93.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |