HUL4 (YJR036C)


Gene profile

Gene name: HUL4
Reference locus (S288C): YJR036C
Gene biotype: protein_coding

Description: Protein with similarity to hect domain E3 ubiquitin-protein ligases; not essential for viability; found in association with Trf4 in TRAMP complex; Belongs to the HUL4 family

Top 10 interactors (score): RPN10 (0.983); RKR1 (0.974); RAD6 (0.95); PKP2 (0.831); PKP1 (0.823); CDC45 (0.819); YBR062C (0.772); RAD23 (0.764); CUE2 (0.745); MAG2 (0.721); TAD1 (0.712); UBC1 (0.698); UBC4 (0.692); EST2 (0.675); YKR073C (0.672); YMR075C-A (0.671); DSK2 (0.659); ASR1 (0.658); CBF5 (0.652); SBA1 (0.647)

Homologues (species, bitscore): HECTD2 (Homo sapiens, 271.2); Hectd2 (Mus musculus, 278.9); hectd2 (Danio rerio, 282.0); ube3a (Xenopus tropicalis, 266.2); Ube3a (Drosophila melanogaster, 250.4); herc-1 (Caenorhabditis elegans, 173.7); UPL1 (Arabidopsis thaliana, 186.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:472411-475089:- gene-YJR036C_AKU4011 rna-NM_001181694.3_AKU4011 cds-NP_012570.3_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:137864-140542:+ gene-YJR036C_BG1 rna-NM_001181694.3_BG1 cds-NP_012570.3_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:486449-489127:- gene-YJR036C_Bruggeman rna-NM_001181694.3_Bruggeman cds-NP_012570.3_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:490379-493057:- gene-YJR036C_CAT1 rna-NM_001181694.3_CAT1 cds-NP_012570.3_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:483990-486668:- gene-YJR036C_CBS1585 rna-NM_001181694.3_CBS1585 cds-NP_012570.3_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:502940-505618:- gene-YJR036C_CBS436 rna-NM_001181694.3_CBS436 cds-NP_012570.3_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:472196-474874:- gene-YJR036C_CBS6412 rna-NM_001181694.3_CBS6412 cds-NP_012570.3_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:474441-477119:- gene-YJR036C_CBS6413 rna-NM_001181694.3_CBS6413 cds-NP_012570.3_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:483081-485759:- gene-YJR036C_CENPK1137D rna-NM_001181694.3_CENPK1137D cds-NP_012570.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:477341-480019:- gene-YJR036C_EthanolRed rna-NM_001181694.3_EthanolRed cds-NP_012570.3_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:488558-491236:- gene-YJR036C_FaliES1 rna-NM_001181694.3_FaliES1 cds-NP_012570.3_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000250.1:3408-6086:- gene-YJR036C_JAY291 rna-NM_001181694.3_JAY291 cds-NP_012570.3_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:486759-489437:- gene-YJR036C_MUCL30387 rna-NM_001181694.3_MUCL30387 cds-NP_012570.3_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:483306-485984:- gene-YJR036C_MUCL30388 rna-NM_001181694.3_MUCL30388 cds-NP_012570.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:477450-480128:- gene-YJR036C_MUCL39482 rna-NM_001181694.3_MUCL39482 cds-NP_012570.3_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:482713-485391:- gene-YJR036C_MUCL42920 rna-NM_001181694.3_MUCL42920 cds-NP_012570.3_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:500692-503370:- gene-YJR036C_NCIM3186 rna-NM_001181694.3_NCIM3186 cds-NP_012570.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:475293-477971:- gene-YJR036C_NCYC1407 rna-NM_001181694.3_NCYC1407 cds-NP_012570.3_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:493629-496307:- gene-YJR036C_PE2H3 rna-NM_001181694.3_PE2H3 cds-NP_012570.3_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:487325-490003:- gene-YJR036C_PE2H4 rna-NM_001181694.3_PE2H4 cds-NP_012570.3_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:500713-503391:- gene-YJR036C_S288C rna-NM_001181694.3_S288C cds-NP_012570.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:285220-287898:- gene-YJR036C_SA1 rna-NM_001181694.3_SA1 cds-NP_012570.3_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:482246-484924:- gene-YJR036C_ThermosaccDry rna-NM_001181694.3_ThermosaccDry cds-NP_012570.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:484479-487157:- gene-YJR036C_VR1 rna-NM_001181694.3_VR1 cds-NP_012570.3_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:462132-464810:- gene-YJR036C_ZTW1 rna-NM_001181694.3_ZTW1 cds-NP_012570.3_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:486866-489541:- gene-YJR036C_Sparadoxus rna-NM_001181694.3_Sparadoxus cds-NP_012570.3_Sparadoxus 88.7 99.6 Verified 1 1 1 False True False False False

Additional files