Gene name: HUG1
Reference locus (S288C): YML058W-A
Gene biotype: protein_coding
Description: MEC1-mediated checkpoint protein HUG1; Ribonucleotide reductase inhibitor; intrinsically disordered protein that binds to and inhibits Rnr2p; involved in the Mec1p-mediated checkpoint pathway; transcription is induced by genotoxic stress and by activation of the Rad53p pathway; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): RNR2 (0.947); RNR3 (0.918); MEC1 (0.856); RNR4 (0.842); DUN1 (0.816); DIF1 (0.766); SML1 (0.749); RAD53 (0.746); RNR1 (0.744); DNA2 (0.741); FSH3 (0.711); RFX1 (0.699); CYC8 (0.693); TUP1 (0.682); YLR297W (0.671); DIN7 (0.611); WTM1 (0.57); SRL4 (0.525); UGX2 (0.48); DSE3 (0.452)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:152501-152707:+ | gene-YML058W-A_AKU4011 | rna-NM_001184439.1_AKU4011 | cds-NP_219498.1_AKU4011 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:323471-323677:- | gene-YML058W-A_BG1 | rna-NM_001184439.1_BG1 | cds-NP_219498.1_BG1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:158636-158842:+ | gene-YML058W-A_Bruggeman | rna-NM_001184439.1_Bruggeman | cds-NP_219498.1_Bruggeman | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:160301-160507:+ | gene-YML058W-A_CAT1 | rna-NM_001184439.1_CAT1 | cds-NP_219498.1_CAT1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:152512-152718:+ | gene-YML058W-A_CBS1585 | rna-NM_001184439.1_CBS1585 | cds-NP_219498.1_CBS1585 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:158397-158603:+ | gene-YML058W-A_CBS436 | rna-NM_001184439.1_CBS436 | cds-NP_219498.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:153220-153426:+ | gene-YML058W-A_CBS6412 | rna-NM_001184439.1_CBS6412 | cds-NP_219498.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:151694-151900:+ | gene-YML058W-A_CBS6413 | rna-NM_001184439.1_CBS6413 | cds-NP_219498.1_CBS6413 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:153476-153682:+ | gene-YML058W-A_CENPK1137D | rna-NM_001184439.1_CENPK1137D | cds-NP_219498.1_CENPK1137D | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:152775-152981:+ | gene-YML058W-A_EthanolRed | rna-NM_001184439.1_EthanolRed | cds-NP_219498.1_EthanolRed | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:153280-153486:+ | gene-YML058W-A_FaliES1 | rna-NM_001184439.1_FaliES1 | cds-NP_219498.1_FaliES1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000366.1:3640-3846:- | gene-YML058W-A_JAY291 | rna-NM_001184439.1_JAY291 | cds-NP_219498.1_JAY291 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:157155-157361:+ | gene-YML058W-A_MUCL30387 | rna-NM_001184439.1_MUCL30387 | cds-NP_219498.1_MUCL30387 | 98.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:160342-160548:+ | gene-YML058W-A_MUCL30388 | rna-NM_001184439.1_MUCL30388 | cds-NP_219498.1_MUCL30388 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:152522-152728:+ | gene-YML058W-A_MUCL39482 | rna-NM_001184439.1_MUCL39482 | cds-NP_219498.1_MUCL39482 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:158340-158546:+ | gene-YML058W-A_MUCL42920 | rna-NM_001184439.1_MUCL42920 | cds-NP_219498.1_MUCL42920 | 98.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:158714-158920:+ | gene-YML058W-A_NCIM3186 | rna-NM_001184439.1_NCIM3186 | cds-NP_219498.1_NCIM3186 | 98.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:153315-153521:+ | gene-YML058W-A_NCYC1407 | rna-NM_001184439.1_NCYC1407 | cds-NP_219498.1_NCYC1407 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:158709-158915:+ | gene-YML058W-A_PE2H3 | rna-NM_001184439.1_PE2H3 | cds-NP_219498.1_PE2H3 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:158573-158779:+ | gene-YML058W-A_PE2H4 | rna-NM_001184439.1_PE2H4 | cds-NP_219498.1_PE2H4 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:158760-158966:+ | gene-YML058W-A_S288C | rna-NM_001184439.1_S288C | cds-NP_219498.1_S288C | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000041.1:25257-25463:- | gene-YML058W-A_SA1 | rna-NM_001184439.1_SA1 | cds-NP_219498.1_SA1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:152573-152779:+ | gene-YML058W-A_ThermosaccDry | rna-NM_001184439.1_ThermosaccDry | cds-NP_219498.1_ThermosaccDry | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:156922-157128:+ | gene-YML058W-A_VR1 | rna-NM_001184439.1_VR1 | cds-NP_219498.1_VR1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:132106-132312:+ | gene-YML058W-A_ZTW1 | rna-NM_001184439.1_ZTW1 | cds-NP_219498.1_ZTW1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:163710-163916:+ | gene-YML058W-A_Sparadoxus | rna-NM_001184439.1_Sparadoxus | cds-NP_219498.1_Sparadoxus | 92.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |