Gene name: HTS1
Reference locus (S288C): YPR033C
Gene biotype: protein_coding
Description: Histidine--tRNA ligase, mitochondrial; Cytoplasmic and mitochondrial histidine tRNA synthetase; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence; mutations in human ortholog HARS2 are associated with Perrault syndrome; Belongs to the class-II aminoacyl-tRNA synthetase family
Top 10 interactors (score): KRS1 (0.998); VAS1 (0.993); THG1 (0.986); MSK1 (0.985); TYS1 (0.982); FRS2 (0.98); THS1 (0.978); ALA1 (0.977); GRS1 (0.974); CDC60 (0.971); GLN4 (0.964); DED81 (0.962); GUS1 (0.957); SLM5 (0.955); WRS1 (0.945); MES1 (0.941); ILS1 (0.941); SUI2 (0.936); FRS1 (0.926); CCT5 (0.91)
Homologues (species, bitscore): HARS (Homo sapiens, 479.9); Hars (Mus musculus, 475.3); hars (Danio rerio, 469.9); hars (Xenopus tropicalis, 409.8); Aats-his (Drosophila melanogaster, 465.3); hars-1 (Caenorhabditis elegans, 393.7); AT3G02760 (Arabidopsis thaliana, 405.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:609038-610678:- | gene-YPR033C_AKU4011 | rna-NM_001184130.1_AKU4011 | cds-NP_015358.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:286986-288626:+ | gene-YPR033C_BG1 | rna-NM_001184130.1_BG1 | cds-NP_015358.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:686699-688339:- | gene-YPR033C_Bruggeman | rna-NM_001184130.1_Bruggeman | cds-NP_015358.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:729668-731308:- | gene-YPR033C_CAT1 | rna-NM_001184130.1_CAT1 | cds-NP_015358.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:612722-614362:- | gene-YPR033C_CBS1585 | rna-NM_001184130.1_CBS1585 | cds-NP_015358.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:627110-628750:- | gene-YPR033C_CBS436 | rna-NM_001184130.1_CBS436 | cds-NP_015358.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:616470-618110:- | gene-YPR033C_CBS6412 | rna-NM_001184130.1_CBS6412 | cds-NP_015358.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:609670-611310:- | gene-YPR033C_CBS6413 | rna-NM_001184130.1_CBS6413 | cds-NP_015358.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:637356-638996:- | gene-YPR033C_CENPK1137D | rna-NM_001184130.1_CENPK1137D | cds-NP_015358.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:606968-608608:- | gene-YPR033C_EthanolRed | rna-NM_001184130.1_EthanolRed | cds-NP_015358.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:614771-616411:- | gene-YPR033C_FaliES1 | rna-NM_001184130.1_FaliES1 | cds-NP_015358.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000116.1:11484-13124:+ | gene-YPR033C_JAY291 | rna-NM_001184130.1_JAY291 | cds-NP_015358.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:627911-629551:- | gene-YPR033C_MUCL30387 | rna-NM_001184130.1_MUCL30387 | cds-NP_015358.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:626592-628232:- | gene-YPR033C_MUCL30388 | rna-NM_001184130.1_MUCL30388 | cds-NP_015358.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:605979-607619:- | gene-YPR033C_MUCL39482 | rna-NM_001184130.1_MUCL39482 | cds-NP_015358.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:668789-670429:- | gene-YPR033C_MUCL42920 | rna-NM_001184130.1_MUCL42920 | cds-NP_015358.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:637362-639002:- | gene-YPR033C_NCIM3186 | rna-NM_001184130.1_NCIM3186 | cds-NP_015358.1_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:613910-615550:- | gene-YPR033C_NCYC1407 | rna-NM_001184130.1_NCYC1407 | cds-NP_015358.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:620140-621780:- | gene-YPR033C_PE2H3 | rna-NM_001184130.1_PE2H3 | cds-NP_015358.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:619788-621428:- | gene-YPR033C_PE2H4 | rna-NM_001184130.1_PE2H4 | cds-NP_015358.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:637379-639019:- | gene-YPR033C_S288C | rna-NM_001184130.1_S288C | cds-NP_015358.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:61756-63396:+ | gene-YPR033C_SA1 | rna-NM_001184130.1_SA1 | cds-NP_015358.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:614571-616211:- | gene-YPR033C_ThermosaccDry | rna-NM_001184130.1_ThermosaccDry | cds-NP_015358.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:630801-632441:- | gene-YPR033C_VR1 | rna-NM_001184130.1_VR1 | cds-NP_015358.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:613891-615531:- | gene-YPR033C_ZTW1 | rna-NM_001184130.1_ZTW1 | cds-NP_015358.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:614690-616315:- | gene-YPR033C_Sparadoxus | rna-NM_001184130.1_Sparadoxus | cds-NP_015358.1_Sparadoxus | 90.0 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |