HSV2 (YGR223C)


Gene profile

Gene name: HSV2
Reference locus (S288C): YGR223C
Gene biotype: protein_coding

Description: SVP1-like protein 2; Phosphatidylinositol 3,5-bisphosphate-binding protein; plays a role in micronucleophagy; belongs to the PROPPIN family of proteins; predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization; Belongs to the WD repeat SVP1 family

Top 10 interactors (score): ATG2 (0.981); ATG9 (0.948); VPS30 (0.92); ATG7 (0.908); ATG5 (0.894); ATG12 (0.851); ATG15 (0.837); VPS34 (0.813); ATG21 (0.801); ATG1 (0.799); ATG8 (0.781); ATG4 (0.766); ATG3 (0.766); VPS15 (0.725); FAB1 (0.719); ATG18 (0.702); ATG13 (0.661); TLG2 (0.644); YLR001C (0.644); CLG1 (0.639)

Homologues (species, bitscore): WDR45B (Homo sapiens, 194.1); Wdr45b (Mus musculus, 193.7); wdr45l (Danio rerio, 194.1); wdr45b (Xenopus tropicalis, 196.1); CG11975 (Drosophila melanogaster, 178.3); atg-18 (Caenorhabditis elegans, 95.9); AtATG18a (Arabidopsis thaliana, 170.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:906171-907517:- gene-YGR223C_AKU4011 rna-NM_001181352.1_AKU4011 cds-NP_011739.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:186394-187740:- gene-YGR223C_BG1 rna-NM_001181352.1_BG1 cds-NP_011739.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:913875-915221:- gene-YGR223C_Bruggeman rna-NM_001181352.1_Bruggeman cds-NP_011739.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:912125-913471:- gene-YGR223C_CAT1 rna-NM_001181352.1_CAT1 cds-NP_011739.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:909121-910467:- gene-YGR223C_CBS1585 rna-NM_001181352.1_CBS1585 cds-NP_011739.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:912803-914149:- gene-YGR223C_CBS436 rna-NM_001181352.1_CBS436 cds-NP_011739.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:899991-901337:- gene-YGR223C_CBS6412 rna-NM_001181352.1_CBS6412 cds-NP_011739.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:906050-907396:- gene-YGR223C_CBS6413 rna-NM_001181352.1_CBS6413 cds-NP_011739.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:940451-941797:- gene-YGR223C_CENPK1137D rna-NM_001181352.1_CENPK1137D cds-NP_011739.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:894501-895847:- gene-YGR223C_EthanolRed rna-NM_001181352.1_EthanolRed cds-NP_011739.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:898892-900238:- gene-YGR223C_FaliES1 rna-NM_001181352.1_FaliES1 cds-NP_011739.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000076.1:130026-131372:+ gene-YGR223C_JAY291 rna-NM_001181352.1_JAY291 cds-NP_011739.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:911790-913136:- gene-YGR223C_MUCL30387 rna-NM_001181352.1_MUCL30387 cds-NP_011739.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:911046-912392:- gene-YGR223C_MUCL30388 rna-NM_001181352.1_MUCL30388 cds-NP_011739.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:904198-905544:- gene-YGR223C_MUCL39482 rna-NM_001181352.1_MUCL39482 cds-NP_011739.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:922750-924096:- gene-YGR223C_MUCL42920 rna-NM_001181352.1_MUCL42920 cds-NP_011739.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:940869-942215:- gene-YGR223C_NCIM3186 rna-NM_001181352.1_NCIM3186 cds-NP_011739.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:899850-901196:- gene-YGR223C_NCYC1407 rna-NM_001181352.1_NCYC1407 cds-NP_011739.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:924790-926136:- gene-YGR223C_PE2H3 rna-NM_001181352.1_PE2H3 cds-NP_011739.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:929899-931245:- gene-YGR223C_PE2H4 rna-NM_001181352.1_PE2H4 cds-NP_011739.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:940869-942215:- gene-YGR223C_S288C rna-NM_001181352.1_S288C cds-NP_011739.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000045.1:59550-60896:+ gene-YGR223C_SA1 rna-NM_001181352.1_SA1 cds-NP_011739.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:919403-920749:- gene-YGR223C_ThermosaccDry rna-NM_001181352.1_ThermosaccDry cds-NP_011739.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:1024217-1025563:- gene-YGR223C_VR1 rna-NM_001181352.1_VR1 cds-NP_011739.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:220839-222185:- gene-YGR223C_ZTW1 rna-NM_001181352.1_ZTW1 cds-NP_011739.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:911553-912905:- gene-YGR223C_Sparadoxus rna-NM_001181352.1_Sparadoxus cds-NP_011739.1_Sparadoxus 87.5 99.9 Mismatch 1 1 1 False True False False False

Additional files