Gene name: HST3
Reference locus (S288C): YOR025W
Gene biotype: protein_coding
Description: NAD-dependent histone deacetylase HST3; Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
Top 10 interactors (score): RTT109 (0.974); PNC1 (0.969); HST4 (0.941); QNS1 (0.922); PNP1 (0.915); ASF1 (0.913); UTR1 (0.909); NPY1 (0.906); URH1 (0.904); AMD2 (0.902); HHT1 (0.897); HHT2 (0.873); MRC1 (0.856); RAD9 (0.853); RTT101 (0.844); SGS1 (0.82); RPD3 (0.816); GCN5 (0.808); RTT107 (0.8); HHF1 (0.787)
Homologues (species, bitscore): SIRT1 (Homo sapiens, 124.0); Sirt1 (Mus musculus, 124.0); sirt1 (Danio rerio, 122.5); sirt1 (Xenopus tropicalis, 129.0); Sir2 (Drosophila melanogaster, 120.9); sir-2.1 (Caenorhabditis elegans, 105.9); SRT2 (Arabidopsis thaliana, 73.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:362430-363773:+ | gene-YOR025W_AKU4011 | rna-NM_001183444.1_AKU4011 | cds-NP_014668.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:178012-179355:+ | gene-YOR025W_BG1 | rna-NM_001183444.1_BG1 | cds-NP_014668.1_BG1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:365174-366517:+ | gene-YOR025W_Bruggeman | rna-NM_001183444.1_Bruggeman | cds-NP_014668.1_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:363330-364673:+ | gene-YOR025W_CAT1 | rna-NM_001183444.1_CAT1 | cds-NP_014668.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:357122-358465:+ | gene-YOR025W_CBS1585 | rna-NM_001183444.1_CBS1585 | cds-NP_014668.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:361481-362824:+ | gene-YOR025W_CBS436 | rna-NM_001183444.1_CBS436 | cds-NP_014668.1_CBS436 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:356475-357818:+ | gene-YOR025W_CBS6412 | rna-NM_001183444.1_CBS6412 | cds-NP_014668.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:363851-365194:+ | gene-YOR025W_CBS6413 | rna-NM_001183444.1_CBS6413 | cds-NP_014668.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:378102-379445:+ | gene-YOR025W_CENPK1137D | rna-NM_001183444.1_CENPK1137D | cds-NP_014668.1_CENPK1137D | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:359132-360475:+ | gene-YOR025W_EthanolRed | rna-NM_001183444.1_EthanolRed | cds-NP_014668.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:362480-363823:+ | gene-YOR025W_FaliES1 | rna-NM_001183444.1_FaliES1 | cds-NP_014668.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000035.1:33128-34471:+ | gene-YOR025W_JAY291 | rna-NM_001183444.1_JAY291 | cds-NP_014668.1_JAY291 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:369563-370906:+ | gene-YOR025W_MUCL30387 | rna-NM_001183444.1_MUCL30387 | cds-NP_014668.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:372996-374339:+ | gene-YOR025W_MUCL30388 | rna-NM_001183444.1_MUCL30388 | cds-NP_014668.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:364605-365948:+ | gene-YOR025W_MUCL39482 | rna-NM_001183444.1_MUCL39482 | cds-NP_014668.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:379420-380763:+ | gene-YOR025W_MUCL42920 | rna-NM_001183444.1_MUCL42920 | cds-NP_014668.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:378108-379451:+ | gene-YOR025W_NCIM3186 | rna-NM_001183444.1_NCIM3186 | cds-NP_014668.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:371307-372650:+ | gene-YOR025W_NCYC1407 | rna-NM_001183444.1_NCYC1407 | cds-NP_014668.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:370148-371491:+ | gene-YOR025W_PE2H3 | rna-NM_001183444.1_PE2H3 | cds-NP_014668.1_PE2H3 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:380527-381870:+ | gene-YOR025W_PE2H4 | rna-NM_001183444.1_PE2H4 | cds-NP_014668.1_PE2H4 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:378219-379562:+ | gene-YOR025W_S288C | rna-NM_001183444.1_S288C | cds-NP_014668.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:346014-347357:+ | gene-YOR025W_SA1 | rna-NM_001183444.1_SA1 | cds-NP_014668.1_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:361020-362363:+ | gene-YOR025W_ThermosaccDry | rna-NM_001183444.1_ThermosaccDry | cds-NP_014668.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:361909-363252:+ | gene-YOR025W_VR1 | rna-NM_001183444.1_VR1 | cds-NP_014668.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:95649-96992:+ | gene-YOR025W_ZTW1 | rna-NM_001183444.1_ZTW1 | cds-NP_014668.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:368186-369532:+ | gene-YOR025W_Sparadoxus | rna-NM_001183444.1_Sparadoxus | cds-NP_014668.1_Sparadoxus | 88.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |