Gene name: HSP82
Reference locus (S288C): YPL240C
Gene biotype: protein_coding
Description: ATP-dependent molecular chaperone HSP82; Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication
Top 10 interactors (score): YDJ1 (0.999); SSA1 (0.999); SSA2 (0.999); STI1 (0.999); AHA1 (0.999); SGT1 (0.999); CDC37 (0.999); HSP104 (0.999); CPR6 (0.999); SBA1 (0.999); PPT1 (0.999); HSC82 (0.999); SIS1 (0.998); CPR7 (0.998); HSP60 (0.998); SSE1 (0.997); TAH1 (0.996); HSF1 (0.996); SSA4 (0.996); HCH1 (0.995)
Homologues (species, bitscore): HSP90AB1 (Homo sapiens, 893.3); Hsp90ab1 (Mus musculus, 894.0); hsp90ab1 (Danio rerio, 889.4); hsp90ab1 (Xenopus tropicalis, 896.0); Hsp83 (Drosophila melanogaster, 880.9); daf-21 (Caenorhabditis elegans, 856.7); HSP90.1 (Arabidopsis thaliana, 924.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:74241-76370:- | gene-YPL240C_AKU4011 | rna-NM_001184054.1_AKU4011 | cds-NP_015084.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000184.1:6-899:+ | gene-YPL240C_BG1 | rna-NM_001184054.1_BG1 | cds-NP_015084.1_BG1 | 41.2 | 41.9 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:98129-100741:- | gene-YPL240C_Bruggeman | rna-NM_001184054.1_Bruggeman | cds-NP_015084.1_Bruggeman | 81.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:96243-98621:- | gene-YPL240C_CAT1 | rna-NM_001184054.1_CAT1 | cds-NP_015084.1_CAT1 | 89.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:78554-80683:- | gene-YPL240C_CBS1585 | rna-NM_001184054.1_CBS1585 | cds-NP_015084.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:92979-95108:- | gene-YPL240C_CBS436 | rna-NM_001184054.1_CBS436 | cds-NP_015084.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:83718-85847:- | gene-YPL240C_CBS6412 | rna-NM_001184054.1_CBS6412 | cds-NP_015084.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:74704-76833:- | gene-YPL240C_CBS6413 | rna-NM_001184054.1_CBS6413 | cds-NP_015084.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:96431-98560:- | gene-YPL240C_CENPK1137D | rna-NM_001184054.1_CENPK1137D | cds-NP_015084.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:73640-75769:- | gene-YPL240C_EthanolRed | rna-NM_001184054.1_EthanolRed | cds-NP_015084.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:80447-82576:- | gene-YPL240C_FaliES1 | rna-NM_001184054.1_FaliES1 | cds-NP_015084.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000293.1:27951-28623:+ | gene-YPL240C_JAY291 | rna-NM_001184054.1_JAY291 | cds-NP_015084.1_JAY291 | 31.5 | 31.5 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:91287-93416:- | gene-YPL240C_MUCL30387 | rna-NM_001184054.1_MUCL30387 | cds-NP_015084.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:89730-91859:- | gene-YPL240C_MUCL30388 | rna-NM_001184054.1_MUCL30388 | cds-NP_015084.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:71684-73813:- | gene-YPL240C_MUCL39482 | rna-NM_001184054.1_MUCL39482 | cds-NP_015084.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:90555-92684:- | gene-YPL240C_MUCL42920 | rna-NM_001184054.1_MUCL42920 | cds-NP_015084.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:96479-98608:- | gene-YPL240C_NCIM3186 | rna-NM_001184054.1_NCIM3186 | cds-NP_015084.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:78131-80260:- | gene-YPL240C_NCYC1407 | rna-NM_001184054.1_NCYC1407 | cds-NP_015084.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:85858-87990:- | gene-YPL240C_PE2H3 | rna-NM_001184054.1_PE2H3 | cds-NP_015084.1_PE2H3 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:85501-87633:- | gene-YPL240C_PE2H4 | rna-NM_001184054.1_PE2H4 | cds-NP_015084.1_PE2H4 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:96496-98625:- | gene-YPL240C_S288C | rna-NM_001184054.1_S288C | cds-NP_015084.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000056.1:38374-40503:- | gene-YPL240C_SA1 | rna-NM_001184054.1_SA1 | cds-NP_015084.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:80448-82577:- | gene-YPL240C_ThermosaccDry | rna-NM_001184054.1_ThermosaccDry | cds-NP_015084.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:320327-322456:- | gene-YPL240C_VR1 | rna-NM_001184054.1_VR1 | cds-NP_015084.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:79992-82121:- | gene-YPL240C_ZTW1 | rna-NM_001184054.1_ZTW1 | cds-NP_015084.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:81553-83685:- | gene-YPL240C_Sparadoxus | rna-NM_001184054.1_Sparadoxus | cds-NP_015084.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |