Gene name: HSP78
Reference locus (S288C): YDR258C
Gene biotype: protein_coding
Description: Atp-dependent clp protease atp-binding subunit clpb; Heat shock protein 78, mitochondrial; Oligomeric mitochondrial matrix chaperone; cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; able to prevent the aggregation of misfolded proteins as well as resolubilize protein aggregates
Top 10 interactors (score): HSP104 (0.999); SIS1 (0.998); STI1 (0.994); HSP42 (0.994); SSA4 (0.993); MDJ1 (0.992); CPR6 (0.992); AHA1 (0.991); SSE2 (0.988); HSP82 (0.982); FES1 (0.971); HSP26 (0.968); NTH1 (0.962); TPS1 (0.959); MGE1 (0.946); HSP10 (0.942); SSA3 (0.942); HSP60 (0.941); SSC1 (0.935); MBF1 (0.934)
Homologues (species, bitscore): CLPB (Homo sapiens, 203.0); Clpb (Mus musculus, 203.0); CLPB (Danio rerio, 127.1); clpb (Xenopus tropicalis, 149.8); CLPB3 (Arabidopsis thaliana, 747.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:928170-930605:- | gene-YDR258C_AKU4011 | rna-NM_001180566.3_AKU4011 | cds-NP_010544.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:194666-197101:+ | gene-YDR258C_BG1 | rna-NM_001180566.3_BG1 | cds-NP_010544.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:960499-962934:- | gene-YDR258C_Bruggeman | rna-NM_001180566.3_Bruggeman | cds-NP_010544.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:947778-950213:- | gene-YDR258C_CAT1 | rna-NM_001180566.3_CAT1 | cds-NP_010544.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:918519-920954:- | gene-YDR258C_CBS1585 | rna-NM_001180566.3_CBS1585 | cds-NP_010544.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:948044-950479:- | gene-YDR258C_CBS436 | rna-NM_001180566.3_CBS436 | cds-NP_010544.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:915279-917714:- | gene-YDR258C_CBS6412 | rna-NM_001180566.3_CBS6412 | cds-NP_010544.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:946373-948808:- | gene-YDR258C_CBS6413 | rna-NM_001180566.3_CBS6413 | cds-NP_010544.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:970731-973166:- | gene-YDR258C_CENPK1137D | rna-NM_001180566.3_CENPK1137D | cds-NP_010544.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:928838-931273:- | gene-YDR258C_EthanolRed | rna-NM_001180566.3_EthanolRed | cds-NP_010544.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:937040-939475:- | gene-YDR258C_FaliES1 | rna-NM_001180566.3_FaliES1 | cds-NP_010544.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000261.1:25540-27975:- | gene-YDR258C_JAY291 | rna-NM_001180566.3_JAY291 | cds-NP_010544.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:946397-948832:- | gene-YDR258C_MUCL30387 | rna-NM_001180566.3_MUCL30387 | cds-NP_010544.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:934427-936862:- | gene-YDR258C_MUCL30388 | rna-NM_001180566.3_MUCL30388 | cds-NP_010544.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:919924-922359:- | gene-YDR258C_MUCL39482 | rna-NM_001180566.3_MUCL39482 | cds-NP_010544.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:859684-862119:- | gene-YDR258C_MUCL42920 | rna-NM_001180566.3_MUCL42920 | cds-NP_010544.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:971731-974166:- | gene-YDR258C_NCIM3186 | rna-NM_001180566.3_NCIM3186 | cds-NP_010544.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:923593-926028:- | gene-YDR258C_NCYC1407 | rna-NM_001180566.3_NCYC1407 | cds-NP_010544.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:939817-942252:- | gene-YDR258C_PE2H3 | rna-NM_001180566.3_PE2H3 | cds-NP_010544.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:945094-947529:- | gene-YDR258C_PE2H4 | rna-NM_001180566.3_PE2H4 | cds-NP_010544.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:971808-974243:- | gene-YDR258C_S288C | rna-NM_001180566.3_S288C | cds-NP_010544.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:177654-180089:- | gene-YDR258C_SA1 | rna-NM_001180566.3_SA1 | cds-NP_010544.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:935194-937629:- | gene-YDR258C_ThermosaccDry | rna-NM_001180566.3_ThermosaccDry | cds-NP_010544.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:950417-952852:- | gene-YDR258C_VR1 | rna-NM_001180566.3_VR1 | cds-NP_010544.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:197938-200373:- | gene-YDR258C_ZTW1 | rna-NM_001180566.3_ZTW1 | cds-NP_010544.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:940569-943004:- | gene-YDR258C_Sparadoxus | rna-NM_001180566.3_Sparadoxus | cds-NP_010544.3_Sparadoxus | 90.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |