HSP60 (YLR259C)


Gene profile

Gene name: HSP60
Reference locus (S288C): YLR259C
Gene biotype: protein_coding

Description: Heat shock protein 60, mitochondrial; Tetradecameric mitochondrial chaperonin; required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated

Top 10 interactors (score): HSP10 (0.999); SSC1 (0.999); HSC82 (0.998); HSP82 (0.998); KAR2 (0.996); ECM10 (0.995); TOM40 (0.991); ATP2 (0.99); MGE1 (0.986); ISC1 (0.978); STI1 (0.972); MAS2 (0.971); RSE1 (0.971); PIM1 (0.969); ACO1 (0.968); PRP9 (0.968); ATP1 (0.967); PRP43 (0.967); SMD2 (0.965); SMX3 (0.965)

Homologues (species, bitscore): HSPD1 (Homo sapiens, 607.1); Hspd1 (Mus musculus, 609.8); hspd1 (Danio rerio, 625.2); hspd1 (Xenopus tropicalis, 604.7); Hsp60 (Drosophila melanogaster, 634.0); hsp-60 (Caenorhabditis elegans, 623.6); HSP60 (Arabidopsis thaliana, 662.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:611572-613290:- gene-YLR259C_AKU4011 rna-NM_001182146.1_AKU4011 cds-NP_013360.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:118600-120318:+ gene-YLR259C_BG1 rna-NM_001182146.1_BG1 cds-NP_013360.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:645818-647536:- gene-YLR259C_Bruggeman rna-NM_001182146.1_Bruggeman cds-NP_013360.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:644963-646681:- gene-YLR259C_CAT1 rna-NM_001182146.1_CAT1 cds-NP_013360.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:647067-648785:- gene-YLR259C_CBS1585 rna-NM_001182146.1_CBS1585 cds-NP_013360.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:631292-633010:- gene-YLR259C_CBS436 rna-NM_001182146.1_CBS436 cds-NP_013360.1_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:610042-611760:- gene-YLR259C_CBS6412 rna-NM_001182146.1_CBS6412 cds-NP_013360.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:647363-649081:- gene-YLR259C_CBS6413 rna-NM_001182146.1_CBS6413 cds-NP_013360.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:647893-649611:- gene-YLR259C_CENPK1137D rna-NM_001182146.1_CENPK1137D cds-NP_013360.1_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:605674-607392:- gene-YLR259C_EthanolRed rna-NM_001182146.1_EthanolRed cds-NP_013360.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:634511-636229:- gene-YLR259C_FaliES1 rna-NM_001182146.1_FaliES1 cds-NP_013360.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000136.1:23124-24842:+ gene-YLR259C_JAY291 rna-NM_001182146.1_JAY291 cds-NP_013360.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:646678-648396:- gene-YLR259C_MUCL30387 rna-NM_001182146.1_MUCL30387 cds-NP_013360.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:651441-653159:- gene-YLR259C_MUCL30388 rna-NM_001182146.1_MUCL30388 cds-NP_013360.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:648048-649766:- gene-YLR259C_MUCL39482 rna-NM_001182146.1_MUCL39482 cds-NP_013360.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:642820-644538:- gene-YLR259C_MUCL42920 rna-NM_001182146.1_MUCL42920 cds-NP_013360.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:663258-664976:- gene-YLR259C_NCIM3186 rna-NM_001182146.1_NCIM3186 cds-NP_013360.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:635035-636753:- gene-YLR259C_NCYC1407 rna-NM_001182146.1_NCYC1407 cds-NP_013360.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:638769-640487:- gene-YLR259C_PE2H3 rna-NM_001182146.1_PE2H3 cds-NP_013360.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:638513-640231:- gene-YLR259C_PE2H4 rna-NM_001182146.1_PE2H4 cds-NP_013360.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:663284-665002:- gene-YLR259C_S288C rna-NM_001182146.1_S288C cds-NP_013360.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:23370-25088:+ gene-YLR259C_SA1 rna-NM_001182146.1_SA1 cds-NP_013360.1_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:636519-638237:- gene-YLR259C_ThermosaccDry rna-NM_001182146.1_ThermosaccDry cds-NP_013360.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:647883-649601:- gene-YLR259C_VR1 rna-NM_001182146.1_VR1 cds-NP_013360.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:160831-162549:- gene-YLR259C_ZTW1 rna-NM_001182146.1_ZTW1 cds-NP_013360.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:622371-624089:- gene-YLR259C_Sparadoxus rna-NM_001182146.1_Sparadoxus cds-NP_013360.1_Sparadoxus 92.9 100.0 Verified 1 1 1 False True False False False

Additional files