Gene name: HSP31
Reference locus (S288C): YDR533C
Gene biotype: protein_coding
Description: Glutathione-independent glyoxalase HSP31; Methylglyoxalase that converts methylglyoxal to D-lactate; involved in oxidative stress resistance, diauxic shift, and stationary phase survival; has similarity to E. coli Hsp31 and C. albicans Glx3p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease and cancer; exists as a dimer and contains a putative metal-binding site; protein abundance increases in response to DNA replication stress; Belongs to the peptidase C56 family. HSP31-like subfamily
Top 10 interactors (score): GLO1 (0.981); GLO2 (0.968); GRE2 (0.963); GLO4 (0.946); YNL134C (0.942); DLD2 (0.9); DLD3 (0.9); DLD1 (0.9); HSP104 (0.85); HSP26 (0.846); HSP42 (0.837); TRP5 (0.834); HSP78 (0.833); DSD1 (0.8); ILV1 (0.8); CHA1 (0.8); HSP12 (0.764); CTT1 (0.758); YMR090W (0.744); SOD1 (0.738)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1441463-1442176:- | gene-YDR533C_AKU4011 | rna-NM_001180841.1_AKU4011 | cds-NP_010822.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:83105-83819:- | gene-YDR533C_BG1 | rna-NM_001180841.1_BG1 | cds-NP_010822.1_BG1 | 98.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1472753-1473466:- | gene-YDR533C_Bruggeman | rna-NM_001180841.1_Bruggeman | cds-NP_010822.1_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1449944-1450658:- | gene-YDR533C_CAT1 | rna-NM_001180841.1_CAT1 | cds-NP_010822.1_CAT1 | 98.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1436191-1436904:- | gene-YDR533C_CBS1585 | rna-NM_001180841.1_CBS1585 | cds-NP_010822.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1455414-1456127:- | gene-YDR533C_CBS436 | rna-NM_001180841.1_CBS436 | cds-NP_010822.1_CBS436 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1431355-1432068:- | gene-YDR533C_CBS6412 | rna-NM_001180841.1_CBS6412 | cds-NP_010822.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1454851-1455564:- | gene-YDR533C_CBS6413 | rna-NM_001180841.1_CBS6413 | cds-NP_010822.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1500123-1500836:- | gene-YDR533C_CENPK1137D | rna-NM_001180841.1_CENPK1137D | cds-NP_010822.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1444719-1445432:- | gene-YDR533C_EthanolRed | rna-NM_001180841.1_EthanolRed | cds-NP_010822.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1448271-1448984:- | gene-YDR533C_FaliES1 | rna-NM_001180841.1_FaliES1 | cds-NP_010822.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:146634-147348:- | gene-YDR533C_JAY291 | rna-NM_001180841.1_JAY291 | cds-NP_010822.1_JAY291 | 98.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1455966-1456679:- | gene-YDR533C_MUCL30387 | rna-NM_001180841.1_MUCL30387 | cds-NP_010822.1_MUCL30387 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1437290-1438003:- | gene-YDR533C_MUCL30388 | rna-NM_001180841.1_MUCL30388 | cds-NP_010822.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1427688-1428401:- | gene-YDR533C_MUCL39482 | rna-NM_001180841.1_MUCL39482 | cds-NP_010822.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1370339-1371052:- | gene-YDR533C_MUCL42920 | rna-NM_001180841.1_MUCL42920 | cds-NP_010822.1_MUCL42920 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1501370-1502083:- | gene-YDR533C_NCIM3186 | rna-NM_001180841.1_NCIM3186 | cds-NP_010822.1_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1440980-1441693:- | gene-YDR533C_NCYC1407 | rna-NM_001180841.1_NCYC1407 | cds-NP_010822.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1451903-1452616:- | gene-YDR533C_PE2H3 | rna-NM_001180841.1_PE2H3 | cds-NP_010822.1_PE2H3 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1457371-1458084:- | gene-YDR533C_PE2H4 | rna-NM_001180841.1_PE2H4 | cds-NP_010822.1_PE2H4 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1501447-1502160:- | gene-YDR533C_S288C | rna-NM_001180841.1_S288C | cds-NP_010822.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:114953-115666:+ | gene-YDR533C_SA1 | rna-NM_001180841.1_SA1 | cds-NP_010822.1_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1452493-1453206:- | gene-YDR533C_ThermosaccDry | rna-NM_001180841.1_ThermosaccDry | cds-NP_010822.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1468293-1469006:- | gene-YDR533C_VR1 | rna-NM_001180841.1_VR1 | cds-NP_010822.1_VR1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:495152-495865:- | gene-YDR533C_ZTW1 | rna-NM_001180841.1_ZTW1 | cds-NP_010822.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1461318-1462031:- | gene-YDR533C_Sparadoxus | rna-NM_001180841.1_Sparadoxus | cds-NP_010822.1_Sparadoxus | 89.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |