HSP12 (YFL014W)


Gene profile

Gene name: HSP12
Reference locus (S288C): YFL014W
Gene biotype: protein_coding

Description: 12 kDa heat shock protein; Plasma membrane protein involved in maintaining membrane organization; involved in maintaining organization during stress conditions; induced by heat shock, oxidative stress, osmostress, stationary phase, glucose depletion, oleate and alcohol; protein abundance increased in response to DNA replication stress and dietary restriction; regulated by the HOG and Ras-Pka pathways; required for dietary restriction-induced lifespan extension

Top 10 interactors (score): DDR2 (0.992); CTT1 (0.986); HSP26 (0.964); ALD3 (0.958); MSC1 (0.958); RTC3 (0.955); GAD1 (0.953); PGM2 (0.938); YGP1 (0.937); NQM1 (0.926); HOR7 (0.926); SOL4 (0.926); TFS1 (0.925); STF2 (0.922); DCS2 (0.895); NCE103 (0.889); TSL1 (0.883); RTN2 (0.874); GRE1 (0.872); SSA3 (0.871)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:103690-104019:+ gene-YFL014W_AKU4011 rna-NM_001179952.1_AKU4011 cds-NP_116640.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000203.1:2962-3291:- gene-YFL014W_BG1 rna-NM_001179952.1_BG1 cds-NP_116640.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:103018-103347:+ gene-YFL014W_Bruggeman rna-NM_001179952.1_Bruggeman cds-NP_116640.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:108681-109010:+ gene-YFL014W_CAT1 rna-NM_001179952.1_CAT1 cds-NP_116640.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:104516-104845:+ gene-YFL014W_CBS1585 rna-NM_001179952.1_CBS1585 cds-NP_116640.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:78688-79017:+ gene-YFL014W_CBS436 rna-NM_001179952.1_CBS436 cds-NP_116640.1_CBS436 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:104254-104583:+ gene-YFL014W_CBS6412 rna-NM_001179952.1_CBS6412 cds-NP_116640.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:106768-107097:+ gene-YFL014W_CBS6413 rna-NM_001179952.1_CBS6413 cds-NP_116640.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:103590-103919:+ gene-YFL014W_CENPK1137D rna-NM_001179952.1_CENPK1137D cds-NP_116640.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:102684-103013:+ gene-YFL014W_EthanolRed rna-NM_001179952.1_EthanolRed cds-NP_116640.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:104331-104660:+ gene-YFL014W_FaliES1 rna-NM_001179952.1_FaliES1 cds-NP_116640.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000449.1:5795-6124:+ gene-YFL014W_JAY291 rna-NM_001179952.1_JAY291 cds-NP_116640.1_JAY291 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:104638-104967:+ gene-YFL014W_MUCL30387 rna-NM_001179952.1_MUCL30387 cds-NP_116640.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:102592-102921:+ gene-YFL014W_MUCL30388 rna-NM_001179952.1_MUCL30388 cds-NP_116640.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:102949-103278:+ gene-YFL014W_MUCL39482 rna-NM_001179952.1_MUCL39482 cds-NP_116640.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:102224-102553:+ gene-YFL014W_MUCL42920 rna-NM_001179952.1_MUCL42920 cds-NP_116640.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:107255-107584:+ gene-YFL014W_NCIM3186 rna-NM_001179952.1_NCIM3186 cds-NP_116640.1_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:103981-104310:+ gene-YFL014W_NCYC1407 rna-NM_001179952.1_NCYC1407 cds-NP_116640.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:123827-124156:+ gene-YFL014W_PE2H3 rna-NM_001179952.1_PE2H3 cds-NP_116640.1_PE2H3 98.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:123375-123704:+ gene-YFL014W_PE2H4 rna-NM_001179952.1_PE2H4 cds-NP_116640.1_PE2H4 98.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:107256-107585:+ gene-YFL014W_S288C rna-NM_001179952.1_S288C cds-NP_116640.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000105.1:20025-20354:+ gene-YFL014W_SA1 rna-NM_001179952.1_SA1 cds-NP_116640.1_SA1 98.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:103491-103820:+ gene-YFL014W_ThermosaccDry rna-NM_001179952.1_ThermosaccDry cds-NP_116640.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America MBVZ01000098.1:2691-3020:+ gene-YFL014W_VR1 rna-NM_001179952.1_VR1 cds-NP_116640.1_VR1 98.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:33926-34255:+ gene-YFL014W_ZTW1 rna-NM_001179952.1_ZTW1 cds-NP_116640.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:128100-128429:+ gene-YFL014W_Sparadoxus rna-NM_001179952.1_Sparadoxus cds-NP_116640.1_Sparadoxus 94.8 100.0 Verified 1 1 1 False True False False False

Additional files