HSM3 (YBR272C)


Gene profile

Gene name: HSM3
Reference locus (S288C): YBR272C
Gene biotype: protein_coding

Description: DNA mismatch repair protein HSM3; Evolutionarily conserved 19S regulatory particle assembly-chaperone; involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); involved in DNA mismatch repair during slow growth; weak similarity to Msh1p; structural study suggests Hsm3p is a scaffold protein for Rpt1p-Rpt2p complex formation; ortholog of human 19S subunit S5b

Top 10 interactors (score): RPT1 (0.999); RPT2 (0.997); RPT5 (0.996); RPT6 (0.994); NAS6 (0.993); NAS2 (0.993); RPN14 (0.991); RPT3 (0.989); RPT4 (0.983); RPN1 (0.981); RPN13 (0.972); RPN2 (0.954); RPN12 (0.946); RPN6 (0.946); RPN9 (0.944); RPN3 (0.942); RPN5 (0.94); RPN10 (0.934); RPN8 (0.925); RAD2 (0.862)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:730644-732082:- gene-YBR272C_AKU4011 rna-NM_001178620.3_AKU4011 cds-NP_009831.3_AKU4011 99.6 99.7 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000066.1:101664-103102:- gene-YBR272C_BG1 rna-NM_001178620.3_BG1 cds-NP_009831.3_BG1 99.2 99.7 Verified 1 1 0 False False False True False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:731803-733241:- gene-YBR272C_Bruggeman rna-NM_001178620.3_Bruggeman cds-NP_009831.3_Bruggeman 99.3 99.7 Verified 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:735530-736968:- gene-YBR272C_CAT1 rna-NM_001178620.3_CAT1 cds-NP_009831.3_CAT1 99.1 99.7 Verified 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:722210-723648:- gene-YBR272C_CBS1585 rna-NM_001178620.3_CBS1585 cds-NP_009831.3_CBS1585 99.5 99.7 Verified 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:728651-730089:- gene-YBR272C_CBS436 rna-NM_001178620.3_CBS436 cds-NP_009831.3_CBS436 99.2 99.7 Mismatch 1 1 0 False False False True False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:816825-818263:- gene-YBR272C_CBS6412 rna-NM_001178620.3_CBS6412 cds-NP_009831.3_CBS6412 99.5 99.7 Mismatch 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:728258-729696:- gene-YBR272C_CBS6413 rna-NM_001178620.3_CBS6413 cds-NP_009831.3_CBS6413 99.6 99.7 Verified 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:740265-741703:- gene-YBR272C_CENPK1137D rna-NM_001178620.3_CENPK1137D cds-NP_009831.3_CENPK1137D 99.6 99.7 Verified 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:853679-855117:- gene-YBR272C_EthanolRed rna-NM_001178620.3_EthanolRed cds-NP_009831.3_EthanolRed 99.6 99.7 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:747026-748464:- gene-YBR272C_FaliES1 rna-NM_001178620.3_FaliES1 cds-NP_009831.3_FaliES1 99.6 99.7 Verified 1 1 0 False False False True False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000067.1:55597-57035:+ gene-YBR272C_JAY291 rna-NM_001178620.3_JAY291 cds-NP_009831.3_JAY291 99.3 99.7 Verified 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:733846-735284:- gene-YBR272C_MUCL30387 rna-NM_001178620.3_MUCL30387 cds-NP_009831.3_MUCL30387 99.3 99.7 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:750927-752365:- gene-YBR272C_MUCL30388 rna-NM_001178620.3_MUCL30388 cds-NP_009831.3_MUCL30388 99.3 99.7 Verified 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:720517-721955:- gene-YBR272C_MUCL39482 rna-NM_001178620.3_MUCL39482 cds-NP_009831.3_MUCL39482 99.5 99.7 Verified 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:730383-731821:- gene-YBR272C_MUCL42920 rna-NM_001178620.3_MUCL42920 cds-NP_009831.3_MUCL42920 99.3 99.7 Verified 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:746158-747600:- gene-YBR272C_NCIM3186 rna-NM_001178620.3_NCIM3186 cds-NP_009831.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:722406-723844:- gene-YBR272C_NCYC1407 rna-NM_001178620.3_NCYC1407 cds-NP_009831.3_NCYC1407 99.5 99.7 Verified 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:745532-746970:- gene-YBR272C_PE2H3 rna-NM_001178620.3_PE2H3 cds-NP_009831.3_PE2H3 99.3 99.7 Verified 1 1 0 False False False True False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:743208-744646:- gene-YBR272C_PE2H4 rna-NM_001178620.3_PE2H4 cds-NP_009831.3_PE2H4 99.3 99.7 Verified 1 1 0 False False False True False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:746361-747803:- gene-YBR272C_S288C rna-NM_001178620.3_S288C cds-NP_009831.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000019.1:101486-102924:- gene-YBR272C_SA1 rna-NM_001178620.3_SA1 cds-NP_009831.3_SA1 99.2 99.7 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:746018-747456:- gene-YBR272C_ThermosaccDry rna-NM_001178620.3_ThermosaccDry cds-NP_009831.3_ThermosaccDry 99.6 99.7 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:726230-727668:- gene-YBR272C_VR1 rna-NM_001178620.3_VR1 cds-NP_009831.3_VR1 99.2 99.7 Verified 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:718863-720301:- gene-YBR272C_ZTW1 rna-NM_001178620.3_ZTW1 cds-NP_009831.3_ZTW1 99.6 99.7 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:762774-764212:- gene-YBR272C_Sparadoxus rna-NM_001178620.3_Sparadoxus cds-NP_009831.3_Sparadoxus 88.1 99.7 Verified 1 1 0 False False False True False

Additional files