Gene name: HSL7
Reference locus (S288C): YBR133C
Gene biotype: protein_coding
Description: Protein arginine N-methyltransferase; exhibits septin and Hsl1p-dependent localization to the bud neck in budded cells and periodic Hsl1p-dependent phosphorylation; required with Hsl1p, and Elm1p for the mother-bud neck recruitment, phosphorylation, and degradation of Swe1p; interacts directly with Swe1p; relocalizes away from bud neck upon DNA replication stress; human homolog PRMT5 can complement yeast hsl7 mutant
Top 10 interactors (score): SWE1 (0.999); HSL1 (0.999); PFS2 (0.997); RIO1 (0.996); HMT1 (0.989); MIH1 (0.966); PRP8 (0.965); RMT2 (0.963); NOP1 (0.96); HHF1 (0.925); HHF2 (0.925); PWP2 (0.896); CLB2 (0.896); UTP22 (0.89); SMD3 (0.887); SMD1 (0.885); STE20 (0.881); RPD3 (0.865); HOG1 (0.858); SMB1 (0.835)
Homologues (species, bitscore): PRMT5 (Homo sapiens, 243.8); Prmt5 (Mus musculus, 241.5); prmt5 (Danio rerio, 229.2); prmt5 (Xenopus tropicalis, 251.5); csul (Drosophila melanogaster, 177.6); prmt-5 (Caenorhabditis elegans, 203.4); SKB1 (Arabidopsis thaliana, 236.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:484694-487177:- | gene-YBR133C_AKU4011 | rna-NM_001178481.1_AKU4011 | cds-NP_009691.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:475258-477741:- | gene-YBR133C_BG1 | rna-NM_001178481.1_BG1 | cds-NP_009691.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:486500-488983:- | gene-YBR133C_Bruggeman | rna-NM_001178481.1_Bruggeman | cds-NP_009691.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:381835-384318:- | gene-YBR133C_CAT1 | rna-NM_001178481.1_CAT1 | cds-NP_009691.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:476474-478957:- | gene-YBR133C_CBS1585 | rna-NM_001178481.1_CBS1585 | cds-NP_009691.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:484581-487064:- | gene-YBR133C_CBS436 | rna-NM_001178481.1_CBS436 | cds-NP_009691.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:574340-576823:- | gene-YBR133C_CBS6412 | rna-NM_001178481.1_CBS6412 | cds-NP_009691.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:482109-484592:- | gene-YBR133C_CBS6413 | rna-NM_001178481.1_CBS6413 | cds-NP_009691.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:495575-498058:- | gene-YBR133C_CENPK1137D | rna-NM_001178481.1_CENPK1137D | cds-NP_009691.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:610713-613196:- | gene-YBR133C_EthanolRed | rna-NM_001178481.1_EthanolRed | cds-NP_009691.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:500725-503208:- | gene-YBR133C_FaliES1 | rna-NM_001178481.1_FaliES1 | cds-NP_009691.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000444.1:24182-26665:- | gene-YBR133C_JAY291 | rna-NM_001178481.1_JAY291 | cds-NP_009691.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:489373-491856:- | gene-YBR133C_MUCL30387 | rna-NM_001178481.1_MUCL30387 | cds-NP_009691.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:488661-491144:- | gene-YBR133C_MUCL30388 | rna-NM_001178481.1_MUCL30388 | cds-NP_009691.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:474861-477344:- | gene-YBR133C_MUCL39482 | rna-NM_001178481.1_MUCL39482 | cds-NP_009691.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:484764-487247:- | gene-YBR133C_MUCL42920 | rna-NM_001178481.1_MUCL42920 | cds-NP_009691.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:501601-504084:- | gene-YBR133C_NCIM3186 | rna-NM_001178481.1_NCIM3186 | cds-NP_009691.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:477400-479883:- | gene-YBR133C_NCYC1407 | rna-NM_001178481.1_NCYC1407 | cds-NP_009691.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:490027-492510:- | gene-YBR133C_PE2H3 | rna-NM_001178481.1_PE2H3 | cds-NP_009691.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:487703-490186:- | gene-YBR133C_PE2H4 | rna-NM_001178481.1_PE2H4 | cds-NP_009691.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:501804-504287:- | gene-YBR133C_S288C | rna-NM_001178481.1_S288C | cds-NP_009691.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000032.1:22983-25466:- | gene-YBR133C_SA1 | rna-NM_001178481.1_SA1 | cds-NP_009691.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:499738-502221:- | gene-YBR133C_ThermosaccDry | rna-NM_001178481.1_ThermosaccDry | cds-NP_009691.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:481232-483715:- | gene-YBR133C_VR1 | rna-NM_001178481.1_VR1 | cds-NP_009691.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:474886-477369:- | gene-YBR133C_ZTW1 | rna-NM_001178481.1_ZTW1 | cds-NP_009691.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:512143-514626:- | gene-YBR133C_Sparadoxus | rna-NM_001178481.1_Sparadoxus | cds-NP_009691.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |