Gene name: HSL1
Reference locus (S288C): YKL101W
Gene biotype: protein_coding
Description: Probable serine/threonine-protein kinase HSL1; Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p
Top 10 interactors (score): HSL7 (0.999); MIH1 (0.995); SWE1 (0.991); CDC12 (0.969); CLB2 (0.958); CDC3 (0.947); CDC11 (0.938); CDH1 (0.925); CDC20 (0.913); HOG1 (0.913); CDC10 (0.869); ELM1 (0.868); GIN4 (0.859); CLA4 (0.833); SHS1 (0.815); NAP1 (0.81); KCC4 (0.795); ZDS1 (0.779); SIC1 (0.773); CLB3 (0.755)
Homologues (species, bitscore): BRSK1 (Homo sapiens, 308.9); Brsk1 (Mus musculus, 310.1); si:dkey-16p21.7 (Danio rerio, 300.4); brsk1 (Xenopus tropicalis, 285.8); sff (Drosophila melanogaster, 295.4); sad-1 (Caenorhabditis elegans, 300.1); KIN10 (Arabidopsis thaliana, 267.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:235473-240029:+ | gene-YKL101W_AKU4011 | rna-NM_001179667.2_AKU4011 | cds-NP_012821.2_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:212596-217152:+ | gene-YKL101W_BG1 | rna-NM_001179667.2_BG1 | cds-NP_012821.2_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:253650-258206:+ | gene-YKL101W_Bruggeman | rna-NM_001179667.2_Bruggeman | cds-NP_012821.2_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:248443-252999:+ | gene-YKL101W_CAT1 | rna-NM_001179667.2_CAT1 | cds-NP_012821.2_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:247715-252271:+ | gene-YKL101W_CBS1585 | rna-NM_001179667.2_CBS1585 | cds-NP_012821.2_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:246308-250864:+ | gene-YKL101W_CBS436 | rna-NM_001179667.2_CBS436 | cds-NP_012821.2_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:232344-236900:+ | gene-YKL101W_CBS6412 | rna-NM_001179667.2_CBS6412 | cds-NP_012821.2_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:248171-252727:+ | gene-YKL101W_CBS6413 | rna-NM_001179667.2_CBS6413 | cds-NP_012821.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:248561-253117:+ | gene-YKL101W_CENPK1137D | rna-NM_001179667.2_CENPK1137D | cds-NP_012821.2_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:246166-250722:+ | gene-YKL101W_EthanolRed | rna-NM_001179667.2_EthanolRed | cds-NP_012821.2_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:246979-251535:+ | gene-YKL101W_FaliES1 | rna-NM_001179667.2_FaliES1 | cds-NP_012821.2_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:69307-73863:+ | gene-YKL101W_JAY291 | rna-NM_001179667.2_JAY291 | cds-NP_012821.2_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:255443-259999:+ | gene-YKL101W_MUCL30387 | rna-NM_001179667.2_MUCL30387 | cds-NP_012821.2_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:249842-254398:+ | gene-YKL101W_MUCL30388 | rna-NM_001179667.2_MUCL30388 | cds-NP_012821.2_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:247500-252056:+ | gene-YKL101W_MUCL39482 | rna-NM_001179667.2_MUCL39482 | cds-NP_012821.2_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:252137-256693:+ | gene-YKL101W_MUCL42920 | rna-NM_001179667.2_MUCL42920 | cds-NP_012821.2_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:248909-253465:+ | gene-YKL101W_NCIM3186 | rna-NM_001179667.2_NCIM3186 | cds-NP_012821.2_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:247694-252250:+ | gene-YKL101W_NCYC1407 | rna-NM_001179667.2_NCYC1407 | cds-NP_012821.2_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:254782-259338:+ | gene-YKL101W_PE2H3 | rna-NM_001179667.2_PE2H3 | cds-NP_012821.2_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:251068-255624:+ | gene-YKL101W_PE2H4 | rna-NM_001179667.2_PE2H4 | cds-NP_012821.2_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:248920-253476:+ | gene-YKL101W_S288C | rna-NM_001179667.2_S288C | cds-NP_012821.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:165031-169587:+ | gene-YKL101W_SA1 | rna-NM_001179667.2_SA1 | cds-NP_012821.2_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:247684-252240:+ | gene-YKL101W_ThermosaccDry | rna-NM_001179667.2_ThermosaccDry | cds-NP_012821.2_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:247042-251598:+ | gene-YKL101W_VR1 | rna-NM_001179667.2_VR1 | cds-NP_012821.2_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:246247-250804:+ | gene-YKL101W_ZTW1 | rna-NM_001179667.2_ZTW1 | cds-NP_012821.2_ZTW1 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:263211-267782:+ | gene-YKL101W_Sparadoxus | rna-NM_001179667.2_Sparadoxus | cds-NP_012821.2_Sparadoxus | 86.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |