HSK3 (YKL138C-A)


Gene profile

Gene name: HSK3
Reference locus (S288C): YKL138C-A
Gene biotype: protein_coding

Description: Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis

Top 10 interactors (score): SPC34 (0.997); ASK1 (0.996); DAD4 (0.995); DAD2 (0.993); SPC19 (0.991); DAD3 (0.99); DAD1 (0.987); DUO1 (0.984); DAM1 (0.982); IML3 (0.904); CHL4 (0.9); YJL127C-B (0.767); DSN1 (0.757); YIL156W-B (0.754); CMC4 (0.744); ERI1 (0.71); O0508 (0.699); YJL009W (0.698); SPC3 (0.679); YSF3 (0.678)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:171700-171909:- gene-YKL138C-A_AKU4011 rna-NM_001184513.1_AKU4011 cds-NP_690844.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:148863-149072:- gene-YKL138C-A_BG1 rna-NM_001184513.1_BG1 cds-NP_690844.1_BG1 99.5 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:189362-189571:- gene-YKL138C-A_Bruggeman rna-NM_001184513.1_Bruggeman cds-NP_690844.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:184684-184893:- gene-YKL138C-A_CAT1 rna-NM_001184513.1_CAT1 cds-NP_690844.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:183952-184161:- gene-YKL138C-A_CBS1585 rna-NM_001184513.1_CBS1585 cds-NP_690844.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:182540-182749:- gene-YKL138C-A_CBS436 rna-NM_001184513.1_CBS436 cds-NP_690844.1_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:168574-168783:- gene-YKL138C-A_CBS6412 rna-NM_001184513.1_CBS6412 cds-NP_690844.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:184397-184606:- gene-YKL138C-A_CBS6413 rna-NM_001184513.1_CBS6413 cds-NP_690844.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:184447-184656:- gene-YKL138C-A_CENPK1137D rna-NM_001184513.1_CENPK1137D cds-NP_690844.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:182432-182641:- gene-YKL138C-A_EthanolRed rna-NM_001184513.1_EthanolRed cds-NP_690844.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:183244-183453:- gene-YKL138C-A_FaliES1 rna-NM_001184513.1_FaliES1 cds-NP_690844.1_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:5574-5783:- gene-YKL138C-A_JAY291 rna-NM_001184513.1_JAY291 cds-NP_690844.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:191463-191672:- gene-YKL138C-A_MUCL30387 rna-NM_001184513.1_MUCL30387 cds-NP_690844.1_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:185815-186024:- gene-YKL138C-A_MUCL30388 rna-NM_001184513.1_MUCL30388 cds-NP_690844.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:183730-183939:- gene-YKL138C-A_MUCL39482 rna-NM_001184513.1_MUCL39482 cds-NP_690844.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:188123-188332:- gene-YKL138C-A_MUCL42920 rna-NM_001184513.1_MUCL42920 cds-NP_690844.1_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:184792-185001:- gene-YKL138C-A_NCIM3186 rna-NM_001184513.1_NCIM3186 cds-NP_690844.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:183920-184129:- gene-YKL138C-A_NCYC1407 rna-NM_001184513.1_NCYC1407 cds-NP_690844.1_NCYC1407 99.5 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:191042-191251:- gene-YKL138C-A_PE2H3 rna-NM_001184513.1_PE2H3 cds-NP_690844.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:187330-187539:- gene-YKL138C-A_PE2H4 rna-NM_001184513.1_PE2H4 cds-NP_690844.1_PE2H4 99.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:184803-185012:- gene-YKL138C-A_S288C rna-NM_001184513.1_S288C cds-NP_690844.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:101271-101480:- gene-YKL138C-A_SA1 rna-NM_001184513.1_SA1 cds-NP_690844.1_SA1 98.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:183944-184153:- gene-YKL138C-A_ThermosaccDry rna-NM_001184513.1_ThermosaccDry cds-NP_690844.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:183300-183509:- gene-YKL138C-A_VR1 rna-NM_001184513.1_VR1 cds-NP_690844.1_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:182479-182688:- gene-YKL138C-A_ZTW1 rna-NM_001184513.1_ZTW1 cds-NP_690844.1_ZTW1 99.5 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:199181-199390:- gene-YKL138C-A_Sparadoxus rna-NM_001184513.1_Sparadoxus cds-NP_690844.1_Sparadoxus 89.0 100.0 Verified 1 1 1 False True False False False

Additional files