Gene name: HSF1
Reference locus (S288C): YGL073W
Gene biotype: protein_coding
Description: Trimeric heat shock transcription factor; activates multiple genes in response to highly diverse stresses; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; monitors translational status of cell through an RQC (Ribosomal Quality Control)-mediated translation-stress signal; involved in diauxic shift; posttranslationally regulated; human homolog HSF1 with linker region mutations can complement yeast hsf1 mutant; Belongs to the HSF family
Top 10 interactors (score): SSA1 (0.998); HSC82 (0.998); HSP82 (0.996); SSA2 (0.995); SSA3 (0.99); SSA4 (0.987); YAP1 (0.977); MSN2 (0.951); KSS1 (0.944); RIM11 (0.942); FUS3 (0.942); MSN4 (0.926); TOR2 (0.923); TEF1 (0.922); LST8 (0.921); HBS1 (0.914); KOG1 (0.911); SKI7 (0.907); HOG1 (0.904); YAK1 (0.903)
Homologues (species, bitscore): HSF1 (Homo sapiens, 132.9); Hsf1 (Mus musculus, 133.7); hsf1 (Danio rerio, 126.3); hsf1 (Xenopus tropicalis, 136.0); Hsf (Drosophila melanogaster, 112.5); hsf-1 (Caenorhabditis elegans, 94.4); HSF3 (Arabidopsis thaliana, 102.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:371758-374259:+ | gene-YGL073W_AKU4011 | rna-NM_001180938.3_AKU4011 | cds-NP_011442.3_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:31138-33639:- | gene-YGL073W_BG1 | rna-NM_001180938.3_BG1 | cds-NP_011442.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:374239-376740:+ | gene-YGL073W_Bruggeman | rna-NM_001180938.3_Bruggeman | cds-NP_011442.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:371234-373735:+ | gene-YGL073W_CAT1 | rna-NM_001180938.3_CAT1 | cds-NP_011442.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:375303-377804:+ | gene-YGL073W_CBS1585 | rna-NM_001180938.3_CBS1585 | cds-NP_011442.3_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:369428-371929:+ | gene-YGL073W_CBS436 | rna-NM_001180938.3_CBS436 | cds-NP_011442.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:359463-361964:+ | gene-YGL073W_CBS6412 | rna-NM_001180938.3_CBS6412 | cds-NP_011442.3_CBS6412 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:369388-371889:+ | gene-YGL073W_CBS6413 | rna-NM_001180938.3_CBS6413 | cds-NP_011442.3_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:368940-371441:+ | gene-YGL073W_CENPK1137D | rna-NM_001180938.3_CENPK1137D | cds-NP_011442.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:360830-363331:+ | gene-YGL073W_EthanolRed | rna-NM_001180938.3_EthanolRed | cds-NP_011442.3_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:363391-365892:+ | gene-YGL073W_FaliES1 | rna-NM_001180938.3_FaliES1 | cds-NP_011442.3_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000369.1:49086-51587:+ | gene-YGL073W_JAY291 | rna-NM_001180938.3_JAY291 | cds-NP_011442.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:371435-373936:+ | gene-YGL073W_MUCL30387 | rna-NM_001180938.3_MUCL30387 | cds-NP_011442.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:374201-376702:+ | gene-YGL073W_MUCL30388 | rna-NM_001180938.3_MUCL30388 | cds-NP_011442.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:371611-374112:+ | gene-YGL073W_MUCL39482 | rna-NM_001180938.3_MUCL39482 | cds-NP_011442.3_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:199996-202497:- | gene-YGL073W_MUCL42920 | rna-NM_001180938.3_MUCL42920 | cds-NP_011442.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:368753-371254:+ | gene-YGL073W_NCIM3186 | rna-NM_001180938.3_NCIM3186 | cds-NP_011442.3_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:363145-365646:+ | gene-YGL073W_NCYC1407 | rna-NM_001180938.3_NCYC1407 | cds-NP_011442.3_NCYC1407 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:364799-367300:+ | gene-YGL073W_PE2H3 | rna-NM_001180938.3_PE2H3 | cds-NP_011442.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:369837-372338:+ | gene-YGL073W_PE2H4 | rna-NM_001180938.3_PE2H4 | cds-NP_011442.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:368753-371254:+ | gene-YGL073W_S288C | rna-NM_001180938.3_S288C | cds-NP_011442.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000096.1:3903-6404:+ | gene-YGL073W_SA1 | rna-NM_001180938.3_SA1 | cds-NP_011442.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:363642-366143:+ | gene-YGL073W_ThermosaccDry | rna-NM_001180938.3_ThermosaccDry | cds-NP_011442.3_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:474023-476524:+ | gene-YGL073W_VR1 | rna-NM_001180938.3_VR1 | cds-NP_011442.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:361005-363506:+ | gene-YGL073W_ZTW1 | rna-NM_001180938.3_ZTW1 | cds-NP_011442.3_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:366599-369103:+ | gene-YGL073W_Sparadoxus | rna-NM_001180938.3_Sparadoxus | cds-NP_011442.3_Sparadoxus | 88.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |