HSE1 (YHL002W)


Gene profile

Gene name: HSE1
Reference locus (S288C): YHL002W
Gene biotype: protein_coding

Description: Class E vacuolar protein-sorting machinery protein HSE1; Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes

Top 10 interactors (score): VPS27 (0.999); STP22 (0.994); VPS36 (0.986); UBI4 (0.986); VPS24 (0.979); VPS25 (0.974); VPS20 (0.972); VPS28 (0.972); DID4 (0.968); SNF8 (0.968); BRO1 (0.963); EFM4 (0.962); CTF18 (0.962); RPS31 (0.96); MVB12 (0.949); SNF7 (0.941); SRN2 (0.927); DOA4 (0.923); UBP7 (0.9); BBC1 (0.897)

Homologues (species, bitscore): STAM2 (Homo sapiens, 119.8); Stam2 (Mus musculus, 114.8); stam2 (Danio rerio, 108.6); stam2 (Xenopus tropicalis, 115.9); Stam (Drosophila melanogaster, 114.0); stam-1 (Caenorhabditis elegans, 113.2); AT2G38410 (Arabidopsis thaliana, 50.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:91225-92583:+ gene-YHL002W_AKU4011 rna-NM_001179082.1_AKU4011 cds-NP_011861.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:10940-12298:+ gene-YHL002W_BG1 rna-NM_001179082.1_BG1 cds-NP_011861.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:98082-99440:+ gene-YHL002W_Bruggeman rna-NM_001179082.1_Bruggeman cds-NP_011861.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:92066-93424:+ gene-YHL002W_CAT1 rna-NM_001179082.1_CAT1 cds-NP_011861.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:91812-93170:+ gene-YHL002W_CBS1585 rna-NM_001179082.1_CBS1585 cds-NP_011861.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:84310-85668:+ gene-YHL002W_CBS436 rna-NM_001179082.1_CBS436 cds-NP_011861.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:91411-92769:+ gene-YHL002W_CBS6412 rna-NM_001179082.1_CBS6412 cds-NP_011861.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:91137-92495:+ gene-YHL002W_CBS6413 rna-NM_001179082.1_CBS6413 cds-NP_011861.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:95769-97127:+ gene-YHL002W_CENPK1137D rna-NM_001179082.1_CENPK1137D cds-NP_011861.1_CENPK1137D 99.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:91221-92579:+ gene-YHL002W_EthanolRed rna-NM_001179082.1_EthanolRed cds-NP_011861.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:91750-93108:+ gene-YHL002W_FaliES1 rna-NM_001179082.1_FaliES1 cds-NP_011861.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000422.1:864-2222:- gene-YHL002W_JAY291 rna-NM_001179082.1_JAY291 cds-NP_011861.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:94822-96180:+ gene-YHL002W_MUCL30387 rna-NM_001179082.1_MUCL30387 cds-NP_011861.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:96033-97391:+ gene-YHL002W_MUCL30388 rna-NM_001179082.1_MUCL30388 cds-NP_011861.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:90838-92196:+ gene-YHL002W_MUCL39482 rna-NM_001179082.1_MUCL39482 cds-NP_011861.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:94745-96103:+ gene-YHL002W_MUCL42920 rna-NM_001179082.1_MUCL42920 cds-NP_011861.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:102494-103852:+ gene-YHL002W_NCIM3186 rna-NM_001179082.1_NCIM3186 cds-NP_011861.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:90254-91612:+ gene-YHL002W_NCYC1407 rna-NM_001179082.1_NCYC1407 cds-NP_011861.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:92459-93817:+ gene-YHL002W_PE2H3 rna-NM_001179082.1_PE2H3 cds-NP_011861.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:99900-101258:+ gene-YHL002W_PE2H4 rna-NM_001179082.1_PE2H4 cds-NP_011861.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:102612-103970:+ gene-YHL002W_S288C rna-NM_001179082.1_S288C cds-NP_011861.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000075.1:42573-43931:- gene-YHL002W_SA1 rna-NM_001179082.1_SA1 cds-NP_011861.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:92840-94198:+ gene-YHL002W_ThermosaccDry rna-NM_001179082.1_ThermosaccDry cds-NP_011861.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:98386-99744:+ gene-YHL002W_VR1 rna-NM_001179082.1_VR1 cds-NP_011861.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:84005-85363:+ gene-YHL002W_ZTW1 rna-NM_001179082.1_ZTW1 cds-NP_011861.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:90509-91858:+ gene-YHL002W_Sparadoxus rna-NM_001179082.1_Sparadoxus cds-NP_011861.1_Sparadoxus 89.0 99.1 Unannotated 1 1 0 False False False False True

Additional files