Gene name: HRR25
Reference locus (S288C): YPL204W
Gene biotype: protein_coding
Description: Serine/threonine protein kinase hrr25; Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta
Top 10 interactors (score): MAM1 (0.999); LRS4 (0.993); LTV1 (0.992); RIO2 (0.992); CSM1 (0.987); ENP1 (0.974); TSR1 (0.947); PHR1 (0.944); IKI3 (0.935); SIT4 (0.93); NOB1 (0.925); SEC23 (0.89); ELP3 (0.889); EDE1 (0.888); ATG19 (0.874); KTI11 (0.873); CDC7 (0.861); RTS1 (0.859); SEC24 (0.858); KTI12 (0.852)
Homologues (species, bitscore): CSNK1E (Homo sapiens, 440.3); Csnk1e (Mus musculus, 440.3); csnk1e (Danio rerio, 443.0); csnk1e (Xenopus tropicalis, 439.5); dco (Drosophila melanogaster, 424.9); kin-19 (Caenorhabditis elegans, 419.9); CKL9 (Arabidopsis thaliana, 446.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:142148-143632:+ | gene-YPL204W_AKU4011 | rna-NM_001184018.1_AKU4011 | cds-NP_015120.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:347912-349396:+ | gene-YPL204W_BG1 | rna-NM_001184018.1_BG1 | cds-NP_015120.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:167612-169096:+ | gene-YPL204W_Bruggeman | rna-NM_001184018.1_Bruggeman | cds-NP_015120.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:164214-165698:+ | gene-YPL204W_CAT1 | rna-NM_001184018.1_CAT1 | cds-NP_015120.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:146334-147818:+ | gene-YPL204W_CBS1585 | rna-NM_001184018.1_CBS1585 | cds-NP_015120.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:160756-162240:+ | gene-YPL204W_CBS436 | rna-NM_001184018.1_CBS436 | cds-NP_015120.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:151137-152621:+ | gene-YPL204W_CBS6412 | rna-NM_001184018.1_CBS6412 | cds-NP_015120.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:142511-143995:+ | gene-YPL204W_CBS6413 | rna-NM_001184018.1_CBS6413 | cds-NP_015120.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:164223-165707:+ | gene-YPL204W_CENPK1137D | rna-NM_001184018.1_CENPK1137D | cds-NP_015120.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:141266-142750:+ | gene-YPL204W_EthanolRed | rna-NM_001184018.1_EthanolRed | cds-NP_015120.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:148472-149956:+ | gene-YPL204W_FaliES1 | rna-NM_001184018.1_FaliES1 | cds-NP_015120.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000069.1:8372-9856:- | gene-YPL204W_JAY291 | rna-NM_001184018.1_JAY291 | cds-NP_015120.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:159324-160808:+ | gene-YPL204W_MUCL30387 | rna-NM_001184018.1_MUCL30387 | cds-NP_015120.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:157513-158997:+ | gene-YPL204W_MUCL30388 | rna-NM_001184018.1_MUCL30388 | cds-NP_015120.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:139464-140948:+ | gene-YPL204W_MUCL39482 | rna-NM_001184018.1_MUCL39482 | cds-NP_015120.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:158346-159830:+ | gene-YPL204W_MUCL42920 | rna-NM_001184018.1_MUCL42920 | cds-NP_015120.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:164259-165743:+ | gene-YPL204W_NCIM3186 | rna-NM_001184018.1_NCIM3186 | cds-NP_015120.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:145913-147397:+ | gene-YPL204W_NCYC1407 | rna-NM_001184018.1_NCYC1407 | cds-NP_015120.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:153619-155103:+ | gene-YPL204W_PE2H3 | rna-NM_001184018.1_PE2H3 | cds-NP_015120.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:153262-154746:+ | gene-YPL204W_PE2H4 | rna-NM_001184018.1_PE2H4 | cds-NP_015120.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:164276-165760:+ | gene-YPL204W_S288C | rna-NM_001184018.1_S288C | cds-NP_015120.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000095.1:8428-9912:- | gene-YPL204W_SA1 | rna-NM_001184018.1_SA1 | cds-NP_015120.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:148253-149737:+ | gene-YPL204W_ThermosaccDry | rna-NM_001184018.1_ThermosaccDry | cds-NP_015120.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:163162-164646:+ | gene-YPL204W_VR1 | rna-NM_001184018.1_VR1 | cds-NP_015120.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:147771-149255:+ | gene-YPL204W_ZTW1 | rna-NM_001184018.1_ZTW1 | cds-NP_015120.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:149328-150812:+ | gene-YPL204W_Sparadoxus | rna-NM_001184018.1_Sparadoxus | cds-NP_015120.1_Sparadoxus | 92.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |