Gene name: HRQ1
Reference locus (S288C): YDR291W
Gene biotype: protein_coding
Description: ATP-dependent helicase HRQ1; 3'-5' DNA helicase that has DNA strand annealing activity; helicase activity is stimulated by fork structure and 3'-tail length of substrates; acts with Rad4p in nucleotide-excision repair; belongs to the widely conserved RecQ family of proteins which are involved in maintaining genomic integrity; similar to the human RecQ4p implicated in Rothmund-Thomson syndrome (RTS)
Top 10 interactors (score): PSO2 (0.813); FRS1 (0.805); MPH1 (0.784); PIF1 (0.784); IRC3 (0.777); SGS1 (0.733); RAD52 (0.732); RAD4 (0.713); RAD5 (0.704); REV3 (0.7); RAD57 (0.698); XRS2 (0.691); HMI1 (0.687); DCD1 (0.673); RAD51 (0.651); REV7 (0.65); RAD24 (0.64); RAD10 (0.619); RAD55 (0.615); SRS2 (0.615)
Homologues (species, bitscore): RECQL4 (Homo sapiens, 82.0); Recql4 (Mus musculus, 84.3); hfm1 (Danio rerio, 73.9); ddx59 (Xenopus tropicalis, 65.9); RecQ4 (Drosophila melanogaster, 63.5); K02F3.12 (Caenorhabditis elegans, 74.3); AT5G08110 (Arabidopsis thaliana, 446.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:991701-994934:+ | gene-YDR291W_AKU4011 | rna-NM_001180599.3_AKU4011 | cds-NP_010577.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:136612-139845:- | gene-YDR291W_BG1 | rna-NM_001180599.3_BG1 | cds-NP_010577.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1018984-1022217:+ | gene-YDR291W_Bruggeman | rna-NM_001180599.3_Bruggeman | cds-NP_010577.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1005995-1009228:+ | gene-YDR291W_CAT1 | rna-NM_001180599.3_CAT1 | cds-NP_010577.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:986146-989379:+ | gene-YDR291W_CBS1585 | rna-NM_001180599.3_CBS1585 | cds-NP_010577.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1004523-1007756:+ | gene-YDR291W_CBS436 | rna-NM_001180599.3_CBS436 | cds-NP_010577.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:982828-986061:+ | gene-YDR291W_CBS6412 | rna-NM_001180599.3_CBS6412 | cds-NP_010577.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1004066-1007299:+ | gene-YDR291W_CBS6413 | rna-NM_001180599.3_CBS6413 | cds-NP_010577.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1038374-1041607:+ | gene-YDR291W_CENPK1137D | rna-NM_001180599.3_CENPK1137D | cds-NP_010577.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:990240-993473:+ | gene-YDR291W_EthanolRed | rna-NM_001180599.3_EthanolRed | cds-NP_010577.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:998442-1001675:+ | gene-YDR291W_FaliES1 | rna-NM_001180599.3_FaliES1 | cds-NP_010577.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000130.1:16281-19514:+ | gene-YDR291W_JAY291 | rna-NM_001180599.3_JAY291 | cds-NP_010577.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1004500-1007733:+ | gene-YDR291W_MUCL30387 | rna-NM_001180599.3_MUCL30387 | cds-NP_010577.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:991566-994799:+ | gene-YDR291W_MUCL30388 | rna-NM_001180599.3_MUCL30388 | cds-NP_010577.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:977952-981185:+ | gene-YDR291W_MUCL39482 | rna-NM_001180599.3_MUCL39482 | cds-NP_010577.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:917949-921182:+ | gene-YDR291W_MUCL42920 | rna-NM_001180599.3_MUCL42920 | cds-NP_010577.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1039651-1042884:+ | gene-YDR291W_NCIM3186 | rna-NM_001180599.3_NCIM3186 | cds-NP_010577.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:991243-994476:+ | gene-YDR291W_NCYC1407 | rna-NM_001180599.3_NCYC1407 | cds-NP_010577.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1002253-1005486:+ | gene-YDR291W_PE2H3 | rna-NM_001180599.3_PE2H3 | cds-NP_010577.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1007838-1011071:+ | gene-YDR291W_PE2H4 | rna-NM_001180599.3_PE2H4 | cds-NP_010577.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1039728-1042961:+ | gene-YDR291W_S288C | rna-NM_001180599.3_S288C | cds-NP_010577.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:16460-19693:+ | gene-YDR291W_SA1 | rna-NM_001180599.3_SA1 | cds-NP_010577.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1002727-1005960:+ | gene-YDR291W_ThermosaccDry | rna-NM_001180599.3_ThermosaccDry | cds-NP_010577.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1018679-1021912:+ | gene-YDR291W_VR1 | rna-NM_001180599.3_VR1 | cds-NP_010577.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:46857-50090:+ | gene-YDR291W_ZTW1 | rna-NM_001180599.3_ZTW1 | cds-NP_010577.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:998275-1001508:+ | gene-YDR291W_Sparadoxus | rna-NM_001180599.3_Sparadoxus | cds-NP_010577.3_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |