Gene name: HRK1
Reference locus (S288C): YOR267C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase HRK1; Protein kinase; implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): MEC1 (0.875); HAA1 (0.843); TPO2 (0.774); TPO3 (0.752); DPB11 (0.748); SAP30 (0.746); TOF1 (0.742); TEL1 (0.739); YGP1 (0.713); CSM3 (0.711); CDC45 (0.698); RAD24 (0.697); RAD51 (0.679); SIT4 (0.668); RAD17 (0.637); YCH1 (0.623); AQR1 (0.614); ARR2 (0.612); MIH1 (0.612); MCM4 (0.606)
Homologues (species, bitscore): CHEK1 (Homo sapiens, 99.4); Stk33 (Mus musculus, 100.5); chek1 (Danio rerio, 103.6); chek1 (Xenopus tropicalis, 100.5); Pak (Drosophila melanogaster, 99.4); Y43D4A.6 (Caenorhabditis elegans, 100.1); AT1G67580 (Arabidopsis thaliana, 106.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:813363-815678:- | gene-YOR267C_AKU4011 | rna-NM_001183686.1_AKU4011 | cds-NP_014910.1_AKU4011 | 97.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:215392-217644:- | gene-YOR267C_BG1 | rna-NM_001183686.1_BG1 | cds-NP_014910.1_BG1 | 98.1 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:798822-801113:- | gene-YOR267C_Bruggeman | rna-NM_001183686.1_Bruggeman | cds-NP_014910.1_Bruggeman | 97.2 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:799476-801785:- | gene-YOR267C_CAT1 | rna-NM_001183686.1_CAT1 | cds-NP_014910.1_CAT1 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:796346-798697:- | gene-YOR267C_CBS1585 | rna-NM_001183686.1_CBS1585 | cds-NP_014910.1_CBS1585 | 96.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:795040-797346:- | gene-YOR267C_CBS436 | rna-NM_001183686.1_CBS436 | cds-NP_014910.1_CBS436 | 98.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:793131-795550:- | gene-YOR267C_CBS6412 | rna-NM_001183686.1_CBS6412 | cds-NP_014910.1_CBS6412 | 93.7 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:802108-804405:- | gene-YOR267C_CBS6413 | rna-NM_001183686.1_CBS6413 | cds-NP_014910.1_CBS6413 | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:822349-824638:- | gene-YOR267C_CENPK1137D | rna-NM_001183686.1_CENPK1137D | cds-NP_014910.1_CENPK1137D | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:789476-791806:- | gene-YOR267C_EthanolRed | rna-NM_001183686.1_EthanolRed | cds-NP_014910.1_EthanolRed | 97.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:794875-797205:- | gene-YOR267C_FaliES1 | rna-NM_001183686.1_FaliES1 | cds-NP_014910.1_FaliES1 | 97.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:29707-31959:+ | gene-YOR267C_JAY291 | rna-NM_001183686.1_JAY291 | cds-NP_014910.1_JAY291 | 98.1 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:803098-805350:- | gene-YOR267C_MUCL30387 | rna-NM_001183686.1_MUCL30387 | cds-NP_014910.1_MUCL30387 | 98.4 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:811108-813326:- | gene-YOR267C_MUCL30388 | rna-NM_001183686.1_MUCL30388 | cds-NP_014910.1_MUCL30388 | 96.0 | 97.2 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:803680-806042:- | gene-YOR267C_MUCL39482 | rna-NM_001183686.1_MUCL39482 | cds-NP_014910.1_MUCL39482 | 95.9 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:813266-815530:- | gene-YOR267C_MUCL42920 | rna-NM_001183686.1_MUCL42920 | cds-NP_014910.1_MUCL42920 | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:822477-824756:- | gene-YOR267C_NCIM3186 | rna-NM_001183686.1_NCIM3186 | cds-NP_014910.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:803775-806248:- | gene-YOR267C_NCYC1407 | rna-NM_001183686.1_NCYC1407 | cds-NP_014910.1_NCYC1407 | 91.6 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:803075-805327:- | gene-YOR267C_PE2H3 | rna-NM_001183686.1_PE2H3 | cds-NP_014910.1_PE2H3 | 98.1 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:813452-815704:- | gene-YOR267C_PE2H4 | rna-NM_001183686.1_PE2H4 | cds-NP_014910.1_PE2H4 | 98.1 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:822588-824867:- | gene-YOR267C_S288C | rna-NM_001183686.1_S288C | cds-NP_014910.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:232578-234887:- | gene-YOR267C_SA1 | rna-NM_001183686.1_SA1 | cds-NP_014910.1_SA1 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:794058-796388:- | gene-YOR267C_ThermosaccDry | rna-NM_001183686.1_ThermosaccDry | cds-NP_014910.1_ThermosaccDry | 97.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:857515-859767:- | gene-YOR267C_VR1 | rna-NM_001183686.1_VR1 | cds-NP_014910.1_VR1 | 98.1 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:526979-529276:- | gene-YOR267C_ZTW1 | rna-NM_001183686.1_ZTW1 | cds-NP_014910.1_ZTW1 | 97.7 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:799811-802006:- | gene-YOR267C_Sparadoxus | rna-NM_001183686.1_Sparadoxus | cds-NP_014910.1_Sparadoxus | 87.2 | 96.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |