Gene name: HRB1
Reference locus (S288C): YNL004W
Gene biotype: protein_coding
Description: Protein HRB1; Poly(A+) RNA-binding protein; key surveillance factor for the selective export of spliced mRNAs from the nucleus to the cytoplasm; preference for intron-containing genes; similar to Npl3p; HRB1 has a paralog, GBP2, that arose from the whole genome duplication
Top 10 interactors (score): SUB2 (0.959); YRA1 (0.952); THO2 (0.945); THP2 (0.933); HPR1 (0.906); MEX67 (0.893); SHE2 (0.859); MTR10 (0.854); SHE3 (0.813); SKY1 (0.8); MFT1 (0.79); CDC33 (0.79); SCP160 (0.789); PUF6 (0.777); PUF3 (0.772); MYO4 (0.76); NAB2 (0.759); TIF4631 (0.747); MLP1 (0.733); CBC2 (0.726)
Homologues (species, bitscore): PABPC4L (Homo sapiens, 76.6); Pabpc1l (Mus musculus, 78.6); rbm28 (Danio rerio, 75.5); rbm39 (Xenopus tropicalis, 71.2); Caper (Drosophila melanogaster, 68.2); Y55F3AM.3 (Caenorhabditis elegans, 86.7); PAB2 (Arabidopsis thaliana, 92.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:606006-607712:+ | gene-YNL004W_AKU4011 | rna-NM_001182843.1_AKU4011 | cds-NP_014394.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000196.1:7882-9588:- | gene-YNL004W_1_BG1 | Unknown | Unknown | 100.0 | 100.0 | Verified | 2 | 2 | 1 | Unknown | Unknown | Unknown | Unknown | Unknown |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:508431-510137:+ | gene-YNL004W_BG1 | rna-NM_001182843.1_BG1 | cds-NP_014394.2_BG1 | 100.0 | 100.0 | Verified | 2 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:622820-624526:+ | gene-YNL004W_Bruggeman | rna-NM_001182843.1_Bruggeman | cds-NP_014394.2_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:658203-659909:+ | gene-YNL004W_CAT1 | rna-NM_001182843.1_CAT1 | cds-NP_014394.2_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:611703-613409:+ | gene-YNL004W_CBS1585 | rna-NM_001182843.1_CBS1585 | cds-NP_014394.2_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:673734-675440:+ | gene-YNL004W_CBS436 | rna-NM_001182843.1_CBS436 | cds-NP_014394.2_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:601511-603217:+ | gene-YNL004W_CBS6412 | rna-NM_001182843.1_CBS6412 | cds-NP_014394.2_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:602674-604380:+ | gene-YNL004W_CBS6413 | rna-NM_001182843.1_CBS6413 | cds-NP_014394.2_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:616565-618271:+ | gene-YNL004W_CENPK1137D | rna-NM_001182843.1_CENPK1137D | cds-NP_014394.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:608073-609779:+ | gene-YNL004W_EthanolRed | rna-NM_001182843.1_EthanolRed | cds-NP_014394.2_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:598842-600548:+ | gene-YNL004W_FaliES1 | rna-NM_001182843.1_FaliES1 | cds-NP_014394.2_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000008.1:7436-9142:- | gene-YNL004W_JAY291 | rna-NM_001182843.1_JAY291 | cds-NP_014394.2_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:620909-622615:+ | gene-YNL004W_MUCL30387 | rna-NM_001182843.1_MUCL30387 | cds-NP_014394.2_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:661739-663445:+ | gene-YNL004W_MUCL30388 | rna-NM_001182843.1_MUCL30388 | cds-NP_014394.2_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:603211-604917:+ | gene-YNL004W_MUCL39482 | rna-NM_001182843.1_MUCL39482 | cds-NP_014394.2_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:607003-608709:+ | gene-YNL004W_MUCL42920 | rna-NM_001182843.1_MUCL42920 | cds-NP_014394.2_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:622884-624590:+ | gene-YNL004W_NCIM3186 | rna-NM_001182843.1_NCIM3186 | cds-NP_014394.2_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:605464-607170:+ | gene-YNL004W_NCYC1407 | rna-NM_001182843.1_NCYC1407 | cds-NP_014394.2_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:607381-609087:+ | gene-YNL004W_PE2H3 | rna-NM_001182843.1_PE2H3 | cds-NP_014394.2_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:608699-610405:+ | gene-YNL004W_PE2H4 | rna-NM_001182843.1_PE2H4 | cds-NP_014394.2_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:622915-624621:+ | gene-YNL004W_S288C | rna-NM_001182843.1_S288C | cds-NP_014394.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:20606-22312:+ | gene-YNL004W_SA1 | rna-NM_001182843.1_SA1 | cds-NP_014394.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:599182-600888:+ | gene-YNL004W_ThermosaccDry | rna-NM_001182843.1_ThermosaccDry | cds-NP_014394.2_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:641726-643432:+ | gene-YNL004W_VR1 | rna-NM_001182843.1_VR1 | cds-NP_014394.2_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:507996-509702:+ | gene-YNL004W_ZTW1 | rna-NM_001182843.1_ZTW1 | cds-NP_014394.2_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:614172-615885:+ | gene-YNL004W_Sparadoxus | rna-NM_001182843.1_Sparadoxus | cds-NP_014394.2_Sparadoxus | 91.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |