Gene name: HPT1
Reference locus (S288C): YDR399W
Gene biotype: protein_coding
Description: Dimeric hypoxanthine-guanine phosphoribosyltransferase; catalyzes the transfer of the phosphoribosyl portion of 5-phosphoribosyl-alpha-1-pyrophosphate to a purine base (either guanine or hypoxanthine) to form pyrophosphate and a purine nucleotide (either guanosine monophosphate or inosine monophosphate); mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
Top 10 interactors (score): AAH1 (0.998); ADE12 (0.992); GUD1 (0.985); GUK1 (0.985); GUA1 (0.983); ADE17 (0.98); AMD1 (0.979); PNP1 (0.977); IMD3 (0.977); IMD2 (0.976); ISN1 (0.973); ADE16 (0.968); IMD4 (0.958); ADE2 (0.945); HAM1 (0.942); FCY2 (0.937); ADE13 (0.924); XPT1 (0.924); APT1 (0.915); APT2 (0.906)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1210213-1210878:+ | gene-YDR399W_AKU4011 | rna-NM_001180707.3_AKU4011 | cds-NP_010687.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:88693-89358:+ | gene-YDR399W_BG1 | rna-NM_001180707.3_BG1 | cds-NP_010687.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1241094-1241759:+ | gene-YDR399W_Bruggeman | rna-NM_001180707.3_Bruggeman | cds-NP_010687.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1219650-1220315:+ | gene-YDR399W_CAT1 | rna-NM_001180707.3_CAT1 | cds-NP_010687.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1205134-1205799:+ | gene-YDR399W_CBS1585 | rna-NM_001180707.3_CBS1585 | cds-NP_010687.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1223997-1224662:+ | gene-YDR399W_CBS436 | rna-NM_001180707.3_CBS436 | cds-NP_010687.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1201187-1201852:+ | gene-YDR399W_CBS6412 | rna-NM_001180707.3_CBS6412 | cds-NP_010687.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1223042-1223707:+ | gene-YDR399W_CBS6413 | rna-NM_001180707.3_CBS6413 | cds-NP_010687.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1268731-1269396:+ | gene-YDR399W_CENPK1137D | rna-NM_001180707.3_CENPK1137D | cds-NP_010687.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1214620-1215285:+ | gene-YDR399W_EthanolRed | rna-NM_001180707.3_EthanolRed | cds-NP_010687.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1217930-1218595:+ | gene-YDR399W_FaliES1 | rna-NM_001180707.3_FaliES1 | cds-NP_010687.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000181.1:36942-37607:- | gene-YDR399W_JAY291 | rna-NM_001180707.3_JAY291 | cds-NP_010687.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1224656-1225321:+ | gene-YDR399W_MUCL30387 | rna-NM_001180707.3_MUCL30387 | cds-NP_010687.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1206767-1207432:+ | gene-YDR399W_MUCL30388 | rna-NM_001180707.3_MUCL30388 | cds-NP_010687.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1196462-1197127:+ | gene-YDR399W_MUCL39482 | rna-NM_001180707.3_MUCL39482 | cds-NP_010687.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1138896-1139561:+ | gene-YDR399W_MUCL42920 | rna-NM_001180707.3_MUCL42920 | cds-NP_010687.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1269991-1270656:+ | gene-YDR399W_NCIM3186 | rna-NM_001180707.3_NCIM3186 | cds-NP_010687.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1210434-1211099:+ | gene-YDR399W_NCYC1407 | rna-NM_001180707.3_NCYC1407 | cds-NP_010687.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1220562-1221227:+ | gene-YDR399W_PE2H3 | rna-NM_001180707.3_PE2H3 | cds-NP_010687.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1226130-1226795:+ | gene-YDR399W_PE2H4 | rna-NM_001180707.3_PE2H4 | cds-NP_010687.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1270068-1270733:+ | gene-YDR399W_S288C | rna-NM_001180707.3_S288C | cds-NP_010687.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000071.1:37059-37724:- | gene-YDR399W_SA1 | rna-NM_001180707.3_SA1 | cds-NP_010687.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1222192-1222857:+ | gene-YDR399W_ThermosaccDry | rna-NM_001180707.3_ThermosaccDry | cds-NP_010687.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1237369-1238034:+ | gene-YDR399W_VR1 | rna-NM_001180707.3_VR1 | cds-NP_010687.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:264999-265664:+ | gene-YDR399W_ZTW1 | rna-NM_001180707.3_ZTW1 | cds-NP_010687.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1217288-1217953:+ | gene-YDR399W_Sparadoxus | rna-NM_001180707.3_Sparadoxus | cds-NP_010687.3_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |