HPR1 (YDR138W)


Gene profile

Gene name: HPR1
Reference locus (S288C): YDR138W
Gene biotype: protein_coding

Description: Subunit of THO/TREX complexes; this complex couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p

Top 10 interactors (score): SUB2 (0.999); THO2 (0.999); THP2 (0.999); MFT1 (0.995); YRA1 (0.992); TEX1 (0.986); MEX67 (0.97); GBP2 (0.943); HRB1 (0.906); SAC3 (0.902); CDC73 (0.871); ACC1 (0.836); RNH1 (0.808); THO1 (0.807); NAB2 (0.794); STO1 (0.775); NPL3 (0.774); TOP1 (0.765); CBC2 (0.75); RAP1 (0.748)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:701513-703771:+ gene-YDR138W_AKU4011 rna-NM_001180445.1_AKU4011 cds-NP_010422.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:421068-423326:- gene-YDR138W_BG1 rna-NM_001180445.1_BG1 cds-NP_010422.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:733568-735826:+ gene-YDR138W_Bruggeman rna-NM_001180445.1_Bruggeman cds-NP_010422.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:721540-723798:+ gene-YDR138W_CAT1 rna-NM_001180445.1_CAT1 cds-NP_010422.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:692551-694809:+ gene-YDR138W_CBS1585 rna-NM_001180445.1_CBS1585 cds-NP_010422.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:718454-720712:+ gene-YDR138W_CBS436 rna-NM_001180445.1_CBS436 cds-NP_010422.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:688903-691161:+ gene-YDR138W_CBS6412 rna-NM_001180445.1_CBS6412 cds-NP_010422.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:717879-720137:+ gene-YDR138W_CBS6413 rna-NM_001180445.1_CBS6413 cds-NP_010422.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:723016-725274:+ gene-YDR138W_CENPK1137D rna-NM_001180445.1_CENPK1137D cds-NP_010422.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:703276-705534:+ gene-YDR138W_EthanolRed rna-NM_001180445.1_EthanolRed cds-NP_010422.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:710070-712328:+ gene-YDR138W_FaliES1 rna-NM_001180445.1_FaliES1 cds-NP_010422.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000002.1:62215-64473:+ gene-YDR138W_JAY291 rna-NM_001180445.1_JAY291 cds-NP_010422.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:719492-721750:+ gene-YDR138W_MUCL30387 rna-NM_001180445.1_MUCL30387 cds-NP_010422.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:708511-710769:+ gene-YDR138W_MUCL30388 rna-NM_001180445.1_MUCL30388 cds-NP_010422.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:693894-696152:+ gene-YDR138W_MUCL39482 rna-NM_001180445.1_MUCL39482 cds-NP_010422.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:631850-634108:+ gene-YDR138W_MUCL42920 rna-NM_001180445.1_MUCL42920 cds-NP_010422.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:730501-732759:+ gene-YDR138W_NCIM3186 rna-NM_001180445.1_NCIM3186 cds-NP_010422.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:693295-695553:+ gene-YDR138W_NCYC1407 rna-NM_001180445.1_NCYC1407 cds-NP_010422.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:712633-714891:+ gene-YDR138W_PE2H3 rna-NM_001180445.1_PE2H3 cds-NP_010422.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:711938-714196:+ gene-YDR138W_PE2H4 rna-NM_001180445.1_PE2H4 cds-NP_010422.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:730578-732836:+ gene-YDR138W_S288C rna-NM_001180445.1_S288C cds-NP_010422.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:79249-81507:+ gene-YDR138W_SA1 rna-NM_001180445.1_SA1 cds-NP_010422.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:709592-711850:+ gene-YDR138W_ThermosaccDry rna-NM_001180445.1_ThermosaccDry cds-NP_010422.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:722947-725205:+ gene-YDR138W_VR1 rna-NM_001180445.1_VR1 cds-NP_010422.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:707173-709431:+ gene-YDR138W_ZTW1 rna-NM_001180445.1_ZTW1 cds-NP_010422.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:711743-714001:+ gene-YDR138W_Sparadoxus rna-NM_001180445.1_Sparadoxus cds-NP_010422.1_Sparadoxus 85.4 99.7 Verified 1 1 1 False True False False False

Additional files