Gene name: HPM1
Reference locus (S288C): YIL110W
Gene biotype: protein_coding
Description: Protein-histidine n-methyltransferase; AdoMet-dependent methyltransferase; involved in a novel 3-methylhistidine modification of ribosomal protein Rpl3p; seven beta-strand MTase family member; null mutant exhibits a weak vacuolar protein sorting defect and caspofungin resistance; Belongs to the methyltransferase superfamily. METTL18 family
Top 10 interactors (score): EFM4 (0.975); EFM3 (0.956); EFM2 (0.949); EFM6 (0.905); BMT5 (0.883); EFM5 (0.862); RKM2 (0.859); RPL3 (0.849); RKM5 (0.847); RKM3 (0.844); RMT2 (0.823); TAE1 (0.819); RKM1 (0.801); SFM1 (0.783); BMT2 (0.774); HMT1 (0.772); CIC1 (0.771); NNT1 (0.768); BMT6 (0.764); YGR283C (0.757)
Homologues (species, bitscore): METTL18 (Homo sapiens, 79.3); Mettl18 (Mus musculus, 74.7); METTL18 (Danio rerio, 81.6); mettl18 (Xenopus tropicalis, 77.4); CG17219 (Drosophila melanogaster, 72.0); K01A11.2 (Caenorhabditis elegans, 72.8); AT4G14000 (Arabidopsis thaliana, 68.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:157524-158654:+ | gene-YIL110W_AKU4011 | rna-NM_001179458.1_AKU4011 | cds-NP_012156.1_AKU4011 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:20451-21581:+ | gene-YIL110W_BG1 | rna-NM_001179458.1_BG1 | cds-NP_012156.1_BG1 | 99.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:162154-163287:+ | gene-YIL110W_Bruggeman | rna-NM_001179458.1_Bruggeman | cds-NP_012156.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:154196-155329:+ | gene-YIL110W_CAT1 | rna-NM_001179458.1_CAT1 | cds-NP_012156.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:157783-158913:+ | gene-YIL110W_CBS1585 | rna-NM_001179458.1_CBS1585 | cds-NP_012156.1_CBS1585 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:148694-149827:+ | gene-YIL110W_CBS436 | rna-NM_001179458.1_CBS436 | cds-NP_012156.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:155158-156288:+ | gene-YIL110W_CBS6412 | rna-NM_001179458.1_CBS6412 | cds-NP_012156.1_CBS6412 | 99.1 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:148812-149942:+ | gene-YIL110W_CBS6413 | rna-NM_001179458.1_CBS6413 | cds-NP_012156.1_CBS6413 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:147660-148793:+ | gene-YIL110W_CENPK1137D | rna-NM_001179458.1_CENPK1137D | cds-NP_012156.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:142748-143878:+ | gene-YIL110W_EthanolRed | rna-NM_001179458.1_EthanolRed | cds-NP_012156.1_EthanolRed | 99.0 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:158747-159877:+ | gene-YIL110W_FaliES1 | rna-NM_001179458.1_FaliES1 | cds-NP_012156.1_FaliES1 | 99.0 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000025.1:68671-69801:- | gene-YIL110W_JAY291 | rna-NM_001179458.1_JAY291 | cds-NP_012156.1_JAY291 | 99.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:158998-160128:+ | gene-YIL110W_MUCL30387 | rna-NM_001179458.1_MUCL30387 | cds-NP_012156.1_MUCL30387 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:157738-158868:+ | gene-YIL110W_MUCL30388 | rna-NM_001179458.1_MUCL30388 | cds-NP_012156.1_MUCL30388 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:158627-159757:+ | gene-YIL110W_MUCL39482 | rna-NM_001179458.1_MUCL39482 | cds-NP_012156.1_MUCL39482 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:161883-163013:+ | gene-YIL110W_MUCL42920 | rna-NM_001179458.1_MUCL42920 | cds-NP_012156.1_MUCL42920 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:156045-157178:+ | gene-YIL110W_NCIM3186 | rna-NM_001179458.1_NCIM3186 | cds-NP_012156.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:162671-163801:+ | gene-YIL110W_NCYC1407 | rna-NM_001179458.1_NCYC1407 | cds-NP_012156.1_NCYC1407 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:157161-158291:+ | gene-YIL110W_PE2H3 | rna-NM_001179458.1_PE2H3 | cds-NP_012156.1_PE2H3 | 99.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:151194-152327:+ | gene-YIL110W_PE2H4 | rna-NM_001179458.1_PE2H4 | cds-NP_012156.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:156045-157178:+ | gene-YIL110W_S288C | rna-NM_001179458.1_S288C | cds-NP_012156.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000058.1:26185-27315:- | gene-YIL110W_SA1 | rna-NM_001179458.1_SA1 | cds-NP_012156.1_SA1 | 99.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:157404-158534:+ | gene-YIL110W_ThermosaccDry | rna-NM_001179458.1_ThermosaccDry | cds-NP_012156.1_ThermosaccDry | 99.0 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:154311-155441:+ | gene-YIL110W_VR1 | rna-NM_001179458.1_VR1 | cds-NP_012156.1_VR1 | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:132347-133477:+ | gene-YIL110W_ZTW1 | rna-NM_001179458.1_ZTW1 | cds-NP_012156.1_ZTW1 | 99.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:150135-151268:+ | gene-YIL110W_Sparadoxus | rna-NM_001179458.1_Sparadoxus | cds-NP_012156.1_Sparadoxus | 87.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |